eF-site ID 4hbm-A
PDB Code 4hbm
Chain A

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Title Ordering of the N Terminus of Human MDM2 by Small Molecule Inhibitors
Classification ligase/ligase inhibitor
Compound E3 ubiquitin-protein ligase Mdm2
Source Homo sapiens (Human) (MDM2_HUMAN)
Sequence A:  MSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQK
DTYTMKEVLFYLGQYIMTKRLYDEKQQHIVYCSNDLLGDL
FGVPSFSVKEHRKIYTMIYRNLVVVN
Description


Functional site

1) chain A
residue 16
type
sequence T
description BINDING SITE FOR RESIDUE 0Y7 A 201
source : AC1

2) chain A
residue 54
type
sequence L
description BINDING SITE FOR RESIDUE 0Y7 A 201
source : AC1

3) chain A
residue 58
type
sequence G
description BINDING SITE FOR RESIDUE 0Y7 A 201
source : AC1

4) chain A
residue 61
type
sequence I
description BINDING SITE FOR RESIDUE 0Y7 A 201
source : AC1

5) chain A
residue 93
type
sequence V
description BINDING SITE FOR RESIDUE 0Y7 A 201
source : AC1

6) chain A
residue 94
type
sequence K
description BINDING SITE FOR RESIDUE 0Y7 A 201
source : AC1

7) chain A
residue 96
type
sequence H
description BINDING SITE FOR RESIDUE 0Y7 A 201
source : AC1

8) chain A
residue 100
type
sequence Y
description BINDING SITE FOR RESIDUE 0Y7 A 201
source : AC1


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