eF-site ID 4h10-AB PDB Code 4h10 Chain A, B click to enlarge Title Intermolecular recognition revealed by the complex structure of human CLOCK-BMAL1 basic Helix-Loop-Helix domains with E-box DNA Classification TRANSCRIPTION/DNA Compound Aryl hydrocarbon receptor nuclear translocator-like protein 1 Source Homo sapiens (Human) (4H10) Sequence A:  RIKNAREAHSQIEKRRRDKMNSFIDELASLVPTCNAMSRK LDKLTVLRMAVQHMKTLRGA B:  KDKAKRVSRNKSEKKRRDQFNVLIKELGSMLPGNARKMDK STVLQKSIDFLRKHKEITAWLEH Description Functional site 1) chain A residue 85 type SITE sequence R description Interaction with E-box DNA => ECO:0000269|PubMed:23229515 source Swiss-Prot : SWS_FT_FI1 2) chain B residue 39 type SITE sequence R description Interaction with E-box DNA => ECO:0000269|PubMed:23229515 source Swiss-Prot : SWS_FT_FI1 3) chain B residue 43 type SITE sequence E description Interaction with E-box DNA => ECO:0000269|PubMed:23229515 source Swiss-Prot : SWS_FT_FI1 4) chain B residue 47 type SITE sequence R description Interaction with E-box DNA => ECO:0000269|PubMed:23229515 source Swiss-Prot : SWS_FT_FI1 5) chain B residue 84 type SITE sequence H description Important for interaction with BMAL1 => ECO:0000269|PubMed:23229515 source Swiss-Prot : SWS_FT_FI2 6) chain B residue 38 type MOD_RES sequence S description Phosphoserine => ECO:0000250|UniProtKB:O08785 source Swiss-Prot : SWS_FT_FI3 7) chain B residue 42 type MOD_RES sequence S description Phosphoserine => ECO:0000250|UniProtKB:O08785 source Swiss-Prot : SWS_FT_FI3 8) chain B residue 67 type CROSSLNK sequence K description Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO1) => ECO:0000250|UniProtKB:O08785 source Swiss-Prot : SWS_FT_FI4

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