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eF-site ID
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4gl9-G |
PDB Code
|
4gl9 |
Chain
|
G |
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click to enlarge
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Title
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Crystal structure of inhibitory protein SOCS3 in complex with JAK2 kinase domain and fragment of GP130 intracellular domain |
Classification
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transferase/transferase inhibitor |
Compound
|
Tyrosine-protein kinase |
Source
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(4GL9) |
|
Sequence
|
G: |
LKTFSSKSEYQLVVNAVRKLQESGFYWSAVTGGEANLLLS
AEPAGTFLIRDSSDQRHFFTLSVKTQSGTKNLRIQCEGGS
FSLQSDPRSTQPVPRFDCVLKLVHHYMGAYYIYKIPLVLS
RPLSS
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Description
|
(1) |
Tyrosine-protein kinase (E.C.2.7.10.2), GP130, SOCS3
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