eF-site ID 4gbn-ABCD PDB Code 4gbn Chain A, B, C, D click to enlarge Title Crystal structure of aspart insulin at pH 6.5 Classification HORMONE Compound Insulin A chain Source ORGANISM_COMMON: human; ORGANISM_SCIENTIFIC: Homo sapiens; Sequence A:  GIVEQCCTSICSLYQLENYCN B:  FVNQHLCGSHLVEALYLVCGERGFFYTDK C:  GIVEQCCTSICSLYQLENYCN D:  FVNQHLCGSHLVEALYLVCGERGFFYTDKT Description Functional site 1) chain A residue 6 type sequence C description BINDING SITE FOR RESIDUE CRS A 101 source : AC1 2) chain A residue 9 type sequence S description BINDING SITE FOR RESIDUE CRS A 101 source : AC1 3) chain A residue 10 type sequence I description BINDING SITE FOR RESIDUE CRS A 101 source : AC1 4) chain A residue 11 type sequence C description BINDING SITE FOR RESIDUE CRS A 101 source : AC1 5) chain A residue 16 type sequence L description BINDING SITE FOR RESIDUE CRS A 101 source : AC1 6) chain B residue 11 type sequence L description BINDING SITE FOR RESIDUE CRS A 101 source : AC1 7) chain B residue 14 type sequence A description BINDING SITE FOR RESIDUE CRS A 101 source : AC1 8) chain D residue 17 type sequence L description BINDING SITE FOR RESIDUE CRS A 101 source : AC1 9) chain A residue 3 type sequence V description BINDING SITE FOR RESIDUE CRS A 102 source : AC2 10) chain B residue 26 type sequence Y description BINDING SITE FOR RESIDUE CRS A 102 source : AC2 11) chain B residue 28 type sequence D description BINDING SITE FOR RESIDUE CRS A 102 source : AC2 12) chain D residue 21 type sequence E description BINDING SITE FOR RESIDUE CRS A 102 source : AC2 13) chain D residue 23 type sequence G description BINDING SITE FOR RESIDUE CRS A 102 source : AC2 14) chain B residue 10 type sequence H description BINDING SITE FOR RESIDUE ZN B 101 source : AC3 15) chain B residue 10 type sequence H description BINDING SITE FOR RESIDUE ZN B 101 source : AC3 16) chain B residue 10 type sequence H description BINDING SITE FOR RESIDUE ZN B 101 source : AC3 17) chain B residue 10 type sequence H description BINDING SITE FOR RESIDUE CL B 102 source : AC4 18) chain B residue 10 type sequence H description BINDING SITE FOR RESIDUE CL B 102 source : AC4 19) chain B residue 10 type sequence H description BINDING SITE FOR RESIDUE CL B 102 source : AC4 20) chain D residue 10 type sequence H description BINDING SITE FOR RESIDUE ZN D 101 source : AC5 21) chain D residue 10 type sequence H description BINDING SITE FOR RESIDUE ZN D 101 source : AC5 22) chain D residue 10 type sequence H description BINDING SITE FOR RESIDUE ZN D 101 source : AC5 23) chain A residue 6-20 type prosite sequence CCTSICSLYQLENYC description INSULIN Insulin family signature. CCTSiCSlyqLenyC source prosite : PS00262

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