eF-site ID 4g5s-D PDB Code 4g5s Chain D click to enlarge Title Structure of LGN GL3/Galphai3 complex Classification CELL CYCLE/SIGNALING PROTEIN Compound Guanine nucleotide-binding protein G(k) subunit alpha Source Homo sapiens (Human) (GPSM2_MOUSE) Sequence D:  AKEVKLLLLGAGESGKSTIVKQMKIIHEDGYSEDECKQYK VVVYSNTIQSIIAIIRAMGRLKIDFGEAARADDARQLFVL AGSAEVMTPELAGVIKRLWRDGGVQACFSRSREYQLNDSA SYYLNDLDRISQSNYIPTQQDVLRTRVKTTGIVETHFTFK DLYFKMFDVGRKKWIHCFEGVTAIIFCVALSDYDLVLAED EEMNRMHESMKLFDSICNNKWFTETSIILFLNKKDLFEEK IKRSPLTICYPEYTGSNTYEEAAAYIQCQFEDLNRRKDTK EIYTHFTCATDTKNVQFVFDAVTDVIIKNNLKECGL Description Functional site 1) chain D residue 271 type sequence K description BINDING SITE FOR RESIDUE CIT C 402 source : AC5 2) chain D residue 323 type sequence F description BINDING SITE FOR RESIDUE CIT C 402 source : AC5 3) chain D residue 331 type sequence N description BINDING SITE FOR RESIDUE CIT C 402 source : AC5 4) chain D residue 43 type BINDING sequence E description BINDING => ECO:0000269|PubMed:22952234, ECO:0007744|PDB:4G5S source Swiss-Prot : SWS_FT_FI1 5) chain D residue 175 type BINDING sequence L description BINDING => ECO:0000269|PubMed:22952234, ECO:0007744|PDB:4G5S source Swiss-Prot : SWS_FT_FI1 6) chain D residue 269 type BINDING sequence N description BINDING => ECO:0000269|PubMed:22952234, ECO:0007744|PDB:4G5S source Swiss-Prot : SWS_FT_FI1 7) chain D residue 47 type BINDING sequence S description BINDING => ECO:0000269|PubMed:19478087, ECO:0007744|PDB:2V4Z source Swiss-Prot : SWS_FT_FI2 8) chain D residue 181 type BINDING sequence T description BINDING => ECO:0000269|PubMed:19478087, ECO:0007744|PDB:2V4Z source Swiss-Prot : SWS_FT_FI2 9) chain D residue 150 type BINDING sequence D description BINDING => ECO:0007744|PDB:2V4Z, ECO:0007744|PDB:4G5O, ECO:0007744|PDB:4G5R, ECO:0007744|PDB:4G5S source Swiss-Prot : SWS_FT_FI3 10) chain D residue 200 type BINDING sequence D description BINDING => ECO:0000305|PubMed:19478087, ECO:0007744|PDB:2V4Z source Swiss-Prot : SWS_FT_FI4 11) chain D residue 326 type BINDING sequence A description BINDING => ECO:0007744|PDB:2IHB, ECO:0007744|PDB:2ODE, ECO:0007744|PDB:2V4Z, ECO:0007744|PDB:4G5O, ECO:0007744|PDB:4G5R source Swiss-Prot : SWS_FT_FI5 12) chain D residue 178 type MOD_RES sequence R description ADP-ribosylarginine; by cholera toxin => ECO:0000250 source Swiss-Prot : SWS_FT_FI6 13) chain D residue 351 type MOD_RES sequence C description ADP-ribosylcysteine; by pertussis toxin => ECO:0000250 source Swiss-Prot : SWS_FT_FI8

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