eF-site ID 4g5o-C PDB Code 4g5o Chain C click to enlarge Title Structure of LGN GL4/Galphai3(Q147L) complex Classification CELL CYCLE/SIGNALING PROTEIN Compound Guanine nucleotide-binding protein G(k) subunit alpha Source Homo sapiens (Human) (GPSM2_MOUSE) Sequence C:  AKEVKLLLLGAGESGKSTIVKQMKIIHEDGYSEDECKQYK VVVYSNTIQSIIAIIRAMGRLKIDFGEAARADDARQLFVL AGVMTPELAGVIKRLWRDGGVQACFSRSREYLLNDSASYY LNDLDRISQSNYIPTQQDVLRTRVKTTGIVETHFTFKDLY FKMFDVGRSERKKWIHCFEGVTAIIFCVALSDYDLVLADE EMNRMHESMKLFDSICNNKWFTETSIILFLNKKDLFEEKI KRSPLTICYPEYTGSNTYEEAAAYIQCQFEDLNRRKDTKE IYTHFTCATDTKNVQFVFDAVTDVIIKNNLKECGLY Description Functional site 1) chain C residue 41 type sequence A description BINDING SITE FOR RESIDUE GDP C 401 source : BC4 2) chain C residue 42 type sequence G description BINDING SITE FOR RESIDUE GDP C 401 source : BC4 3) chain C residue 43 type sequence E description BINDING SITE FOR RESIDUE GDP C 401 source : BC4 4) chain C residue 44 type sequence S description BINDING SITE FOR RESIDUE GDP C 401 source : BC4 5) chain C residue 45 type sequence G description BINDING SITE FOR RESIDUE GDP C 401 source : BC4 6) chain C residue 46 type sequence K description BINDING SITE FOR RESIDUE GDP C 401 source : BC4 7) chain C residue 47 type sequence S description BINDING SITE FOR RESIDUE GDP C 401 source : BC4 8) chain C residue 48 type sequence T description BINDING SITE FOR RESIDUE GDP C 401 source : BC4 9) chain C residue 150 type sequence D description BINDING SITE FOR RESIDUE GDP C 401 source : BC4 10) chain C residue 151 type sequence S description BINDING SITE FOR RESIDUE GDP C 401 source : BC4 11) chain C residue 176 type sequence R description BINDING SITE FOR RESIDUE GDP C 401 source : BC4 12) chain C residue 178 type sequence R description BINDING SITE FOR RESIDUE GDP C 401 source : BC4 13) chain C residue 269 type sequence N description BINDING SITE FOR RESIDUE GDP C 401 source : BC4 14) chain C residue 270 type sequence K description BINDING SITE FOR RESIDUE GDP C 401 source : BC4 15) chain C residue 272 type sequence D description BINDING SITE FOR RESIDUE GDP C 401 source : BC4 16) chain C residue 273 type sequence L description BINDING SITE FOR RESIDUE GDP C 401 source : BC4 17) chain C residue 325 type sequence C description BINDING SITE FOR RESIDUE GDP C 401 source : BC4 18) chain C residue 326 type sequence A description BINDING SITE FOR RESIDUE GDP C 401 source : BC4 19) chain C residue 271 type sequence K description BINDING SITE FOR RESIDUE CIT C 402 source : BC5 20) chain C residue 322 type sequence H description BINDING SITE FOR RESIDUE CIT C 402 source : BC5 21) chain C residue 323 type sequence F description BINDING SITE FOR RESIDUE CIT C 402 source : BC5 22) chain C residue 331 type sequence N description BINDING SITE FOR RESIDUE CIT C 402 source : BC5 23) chain C residue 335 type sequence V description BINDING SITE FOR RESIDUE CIT C 402 source : BC5 24) chain C residue 33 type sequence E description BINDING SITE FOR RESIDUE SO4 C 403 source : BC6 25) chain C residue 35 type sequence K description BINDING SITE FOR RESIDUE SO4 C 403 source : BC6 26) chain C residue 197 type sequence K description BINDING SITE FOR RESIDUE SO4 C 403 source : BC6 27) chain C residue 199 type sequence F description BINDING SITE FOR RESIDUE SO4 C 403 source : BC6 28) chain C residue 213 type sequence H description BINDING SITE FOR RESIDUE SO4 C 403 source : BC6 29) chain C residue 170 type sequence T description BINDING SITE FOR RESIDUE SO4 C 404 source : BC7 30) chain C residue 171 type sequence Q description BINDING SITE FOR RESIDUE SO4 C 404 source : BC7 31) chain C residue 191 type sequence F description BINDING SITE FOR RESIDUE SO4 C 405 source : BC8 32) chain C residue 192 type sequence K description BINDING SITE FOR RESIDUE SO4 C 405 source : BC8 33) chain C residue 293 type sequence S description BINDING SITE FOR RESIDUE SO4 C 406 source : BC9 34) chain C residue 294 type sequence N description BINDING SITE FOR RESIDUE SO4 C 406 source : BC9 35) chain C residue 275 type sequence E description BINDING SITE FOR RESIDUE CIT D 402 source : CC2 36) chain C residue 295 type sequence T description BINDING SITE FOR RESIDUE CIT D 402 source : CC2 37) chain C residue 296 type sequence Y description BINDING SITE FOR RESIDUE CIT D 402 source : CC2 38) chain C residue 297 type sequence E description BINDING SITE FOR RESIDUE CIT D 402 source : CC2 39) chain C residue 269 type BINDING sequence N description BINDING => ECO:0000269|PubMed:22952234, ECO:0007744|PDB:4G5O, ECO:0007744|PDB:4G5Q source Swiss-Prot : SWS_FT_FI1 40) chain C residue 47 type BINDING sequence S description BINDING => ECO:0000269|PubMed:19478087, ECO:0007744|PDB:2V4Z source Swiss-Prot : SWS_FT_FI2 41) chain C residue 181 type BINDING sequence T description BINDING => ECO:0000269|PubMed:19478087, ECO:0007744|PDB:2V4Z source Swiss-Prot : SWS_FT_FI2 42) chain C residue 150 type BINDING sequence D description BINDING => ECO:0007744|PDB:2V4Z, ECO:0007744|PDB:4G5O, ECO:0007744|PDB:4G5R, ECO:0007744|PDB:4G5S source Swiss-Prot : SWS_FT_FI3 43) chain C residue 200 type BINDING sequence D description BINDING => ECO:0000305|PubMed:19478087, ECO:0007744|PDB:2V4Z source Swiss-Prot : SWS_FT_FI4 44) chain C residue 326 type BINDING sequence A description BINDING => ECO:0007744|PDB:2IHB, ECO:0007744|PDB:2ODE, ECO:0007744|PDB:2V4Z, ECO:0007744|PDB:4G5O, ECO:0007744|PDB:4G5R source Swiss-Prot : SWS_FT_FI5 45) chain C residue 178 type MOD_RES sequence R description ADP-ribosylarginine; by cholera toxin => ECO:0000250 source Swiss-Prot : SWS_FT_FI6 46) chain C residue 351 type MOD_RES sequence C description ADP-ribosylcysteine; by pertussis toxin => ECO:0000250 source Swiss-Prot : SWS_FT_FI8

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