eF-site ID 4g0w-CDEF PDB Code 4g0w Chain C, D, E, F click to enlarge Title Human topoisomerase iibeta in complex with DNA and ametantrone Classification ISOMERASE/DNA/ISOMERASE INHIBITOR Compound DNA topoisomerase 2-beta Source Homo sapiens (Human) (4G0W) Sequence C:  AGCCGAGC D:  TGCAGCTCGGCT E:  AGCCGAGC F:  TGCAGCTCGGCT Description Functional site 1) chain D residue 12 type sequence A description BINDING SITE FOR RESIDUE AKE D 101 source : AC5 2) chain D residue 13 type sequence G description BINDING SITE FOR RESIDUE AKE D 101 source : AC5 3) chain D residue 14 type sequence C description BINDING SITE FOR RESIDUE AKE D 101 source : AC5 4) chain E residue 7 type sequence G description BINDING SITE FOR RESIDUE AKE D 101 source : AC5 5) chain E residue 8 type sequence C description BINDING SITE FOR RESIDUE AKE D 101 source : AC5 6) chain F residue 9 type sequence T description BINDING SITE FOR RESIDUE AKE D 101 source : AC5 7) chain D residue 18 type sequence G description BINDING SITE FOR RESIDUE MG D 102 source : AC6 8) chain C residue 7 type sequence G description BINDING SITE FOR RESIDUE AKE F 101 source : AC7 9) chain C residue 8 type sequence C description BINDING SITE FOR RESIDUE AKE F 101 source : AC7 10) chain D residue 9 type sequence T description BINDING SITE FOR RESIDUE AKE F 101 source : AC7 11) chain F residue 12 type sequence A description BINDING SITE FOR RESIDUE AKE F 101 source : AC7 12) chain F residue 13 type sequence G description BINDING SITE FOR RESIDUE AKE F 101 source : AC7 13) chain F residue 14 type sequence C description BINDING SITE FOR RESIDUE AKE F 101 source : AC7 14) chain F residue 17 type sequence G description BINDING SITE FOR RESIDUE MG F 102 source : AC8

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