eF-site ID 4g0v-CDEF PDB Code 4g0v Chain C, D, E, F click to enlarge Title Human topoisomerase iibeta in complex with DNA and mitoxantrone Classification ISOMERASE/DNA/ISOMERASE INHIBITOR Compound DNA topoisomerase 2-beta Source Homo sapiens (Human) (4G0V) Sequence C:  AGCCGAGC D:  TGCAGCTCGGCT E:  AGCCGAGC F:  TGCAGCTCGGCT Description Functional site 1) chain C residue 8 type sequence C description BINDING SITE FOR RESIDUE MIX A 1301 source : AC1 2) chain D residue 9 type sequence T description BINDING SITE FOR RESIDUE MIX A 1301 source : AC1 3) chain F residue 12 type sequence A description BINDING SITE FOR RESIDUE MIX A 1301 source : AC1 4) chain F residue 13 type sequence G description BINDING SITE FOR RESIDUE MIX A 1301 source : AC1 5) chain F residue 14 type sequence C description BINDING SITE FOR RESIDUE MIX A 1301 source : AC1 6) chain D residue 12 type sequence A description BINDING SITE FOR RESIDUE MIX D 101 source : AC6 7) chain D residue 13 type sequence G description BINDING SITE FOR RESIDUE MIX D 101 source : AC6 8) chain D residue 14 type sequence C description BINDING SITE FOR RESIDUE MIX D 101 source : AC6 9) chain E residue 8 type sequence C description BINDING SITE FOR RESIDUE MIX D 101 source : AC6 10) chain F residue 9 type sequence T description BINDING SITE FOR RESIDUE MIX D 101 source : AC6

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