eF-site ID 4fka-ABCD PDB Code 4fka Chain A, B, C, D click to enlarge Title High resolution structure of the manganese derivative of insulin Classification HORMONE Compound Insulin A chain Source ORGANISM_COMMON: human; ORGANISM_SCIENTIFIC: Homo sapiens; Sequence A:  GIVEQCCTSICSLYQLENYCN B:  FVNQHLCGSHLVEALYLVCGERGFFYTPKT C:  GIVEQCCTSICSLYQLENYCN D:  FVNQHLCGSHLVEALYLVCGERGFFYTPKT Description Functional site 1) chain A residue 12 type sequence S description BINDING SITE FOR RESIDUE NA A 101 source : AC1 2) chain A residue 13 type sequence L description BINDING SITE FOR RESIDUE NA A 101 source : AC1 3) chain B residue 1 type sequence F description BINDING SITE FOR RESIDUE NA A 101 source : AC1 4) chain B residue 2 type sequence V description BINDING SITE FOR RESIDUE NA A 101 source : AC1 5) chain B residue 10 type sequence H description BINDING SITE FOR RESIDUE MN B 101 source : AC2 6) chain B residue 10 type sequence H description BINDING SITE FOR RESIDUE MN B 101 source : AC2 7) chain B residue 10 type sequence H description BINDING SITE FOR RESIDUE MN B 101 source : AC2 8) chain D residue 10 type sequence H description BINDING SITE FOR RESIDUE MN D 101 source : AC3 9) chain D residue 10 type sequence H description BINDING SITE FOR RESIDUE MN D 101 source : AC3 10) chain D residue 10 type sequence H description BINDING SITE FOR RESIDUE MN D 101 source : AC3 11) chain A residue 6-20 type prosite sequence CCTSICSLYQLENYC description INSULIN Insulin family signature. CCTSiCSlyqLenyC source prosite : PS00262

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