|
|
eF-site ID
|
4ezd-A |
|
PDB Code
|
4ezd |
|
Chain
|
A |
|
click to enlarge
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Title
|
Crystal Structure of the UT-B Urea Transporter from Bos Taurus Bound to Selenourea |
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Classification
|
TRANSPORT PROTEIN |
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Compound
|
Urea transporter 1 |
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Source
|
Bos taurus (Bovine) (UT1_BOVIN) |
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Sequence
|
A: |
GYITGDMKEFANWLKDKPQALQFVDWVLRGISQVVFVSNP
ISGILILVGLLVQNPWCALNGCVGTVVSTLTALLLSQDRS
AITAGLQGYNATLVGILMAIYSDKGNYFWWLLFPVSAMSM
TCPVFSSALNSVLSKWDLPVFTLPFNMALSMYLSATGHYN
PFFPSTLITPVTSVPNVTWPDLSALQLLKSLPVGVGQIYG
CDNPWTGGIFLGAILLSSPLMCLHAAIGSLLGIIAGLSLS
APFEDIYAGLWGFNSSLACIAIGGTFMALTWQTHLLALAC
ALFTAYLGASMSHVMAVVGLPSGTWPFCLATLLFLLLTTK
NPNIYKMPISKVTYPEENRIFYLQS
|
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Description
|
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Functional site
|
|
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1)
|
chain |
A |
| residue |
61-81 |
| type |
TRANSMEM |
| sequence |
ISQVVFVSNPISGILILVGLL
|
| description |
Helical => ECO:0000255
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
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2)
|
chain |
A |
| residue |
85-105 |
| type |
TRANSMEM |
| sequence |
PWCALNGCVGTVVSTLTALLL
|
| description |
Helical => ECO:0000255
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
3)
|
chain |
A |
| residue |
111-131 |
| type |
TRANSMEM |
| sequence |
AITAGLQGYNATLVGILMAIY
|
| description |
Helical => ECO:0000255
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
4)
|
chain |
A |
| residue |
138-158 |
| type |
TRANSMEM |
| sequence |
FWWLLFPVSAMSMTCPVFSSA
|
| description |
Helical => ECO:0000255
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
5)
|
chain |
A |
| residue |
237-257 |
| type |
TRANSMEM |
| sequence |
GGIFLGAILLSSPLMCLHAAI
|
| description |
Helical => ECO:0000255
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
6)
|
chain |
A |
| residue |
279-299 |
| type |
TRANSMEM |
| sequence |
GLWGFNSSLACIAIGGTFMAL
|
| description |
Helical => ECO:0000255
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
7)
|
chain |
A |
| residue |
305-325 |
| type |
TRANSMEM |
| sequence |
LLALACALFTAYLGASMSHVM
|
| description |
Helical => ECO:0000255
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
8)
|
chain |
A |
| residue |
327-347 |
| type |
TRANSMEM |
| sequence |
VVGLPSGTWPFCLATLLFLLL
|
| description |
Helical => ECO:0000255
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
9)
|
chain |
A |
| residue |
334 |
| type |
SITE |
| sequence |
T
|
| description |
Important for channel permeability => ECO:0000269|PubMed:22733730
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
10)
|
chain |
A |
| residue |
206 |
| type |
CARBOHYD |
| sequence |
N
|
| description |
N-linked (GlcNAc...) asparagine => ECO:0000255
|
| source |
Swiss-Prot : SWS_FT_FI3
|
|
|
|