eF-site ID 4eop-B PDB Code 4eop Chain B click to enlarge Title Thr 160 phosphorylated CDK2 Q131E - human cyclin A3 complex with the inhibitor RO3306 Classification TRANSFERASE/TRANSFERASE INHIBITOR Compound Cyclin-dependent kinase 2 Source Homo sapiens (Human) (CCNA2_HUMAN) Sequence B:  PDYHEDIHTYLREMEVKCKPKVGYMKKQPDITNSMRAILV DWLVEVGEEYKLQNETLHLAVNYIDRFLSSMSVLRGKLQL VGTAAMLLASKFEEIYPPEVAEFVYITDDTYTKKQVLRME HLVLKVLTFDLAAPTVNQFLTQYFLHQQPANCKVESLAMF LGELSLIDADPYLKYLPSVIAGAAFHLALYTVTGQSWPES LIRKTGYTLESLKPCLMDLHQTYLKAPQHAQQSIREKYKN SKYHGVSLLNPPETLNL Description (1)  Cyclin-dependent kinase 2 (E.C.2.7.11.22), Cyclin-A2 Functional site 1) chain B residue 189 type sequence M description BINDING SITE FOR RESIDUE SGM B 501 source : AC2 2) chain B residue 193 type sequence C description BINDING SITE FOR RESIDUE SGM B 501 source : AC2 3) chain B residue 241 type sequence R description BINDING SITE FOR RESIDUE SGM B 501 source : AC2 4) chain B residue 305 type sequence D description BINDING SITE FOR RESIDUE SGM B 501 source : AC2 5) chain B residue 211-242 type prosite sequence RAILVDWLVEVGEEYKLQNETLHLAVNYIDRF description CYCLINS Cyclins signature. RaiLvdWLvevgeeykLqnetLhlAVnYIDRF source prosite : PS00292

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