|
|
eF-site ID
|
4eok-D |
|
PDB Code
|
4eok |
|
Chain
|
D |
|
click to enlarge
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Title
|
Thr 160 phosphorylated CDK2 H84S, Q85M, K89D - human cyclin A3 complex with the inhibitor NU6102 |
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Classification
|
Transferase/Transferase Inhibitor |
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Compound
|
Cyclin-dependent kinase 2 |
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Source
|
Homo sapiens (Human) (CCNA2_HUMAN) |
|
|
Sequence
|
D: |
PDYHEDIHTYLREMEVKCKPKVGYMKKQPDITNSMRAILV
DWLVEVGEEYKLQNETLHLAVNYIDRFLSSMSVLRGKLQL
VGTAAMLLASKFEEIYPPEVAEFVYITDDTYTKKQVLRME
HLVLKVLTFDLAAPTVNQFLTQYFLHQQPANCKVESLAMF
LGELSLIDADPYLKYLPSVIAGAAFHLALYTVTGQSWPES
LIRKTGYTLESLKPCLMDLHQTYLKAPQHAQQSIREKYKN
SKYHGVSLLNPPETLN
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|
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Description
|
(1) |
Cyclin-dependent kinase 2 (E.C.2.7.11.22), Cyclin-A2
|
|
Functional site
|
|
|
1)
|
chain |
D |
| residue |
192 |
| type |
|
| sequence |
K
|
| description |
BINDING SITE FOR RESIDUE SGM D 501
|
| source |
: AC4
|
|
|
2)
|
chain |
D |
| residue |
193 |
| type |
|
| sequence |
C
|
| description |
BINDING SITE FOR RESIDUE SGM D 501
|
| source |
: AC4
|
|
|
3)
|
chain |
D |
| residue |
241 |
| type |
|
| sequence |
R
|
| description |
BINDING SITE FOR RESIDUE SGM D 501
|
| source |
: AC4
|
|
|
4)
|
chain |
D |
| residue |
305 |
| type |
|
| sequence |
D
|
| description |
BINDING SITE FOR RESIDUE SGM D 501
|
| source |
: AC4
|
|
|
|