eF-site ID 4em9-B PDB Code 4em9 Chain B click to enlarge Title Human PPAR gamma in complex with nonanoic acids Classification TRANSCRIPTION Compound Peroxisome proliferator-activated receptor gamma Source Homo sapiens (Human) (PPARG_HUMAN) Sequence B:  ESADLRALAKHLYDSYIKSFPLTKAKARAILTGSPFVIYD MNSLMMGEDFKHIEVAIRIFQGCQFRSVEAVQEITEYAKS IPGFVNLDLNDQVTLLKYGVHEIIYTMLASLMNKDGVLIS EGQGFMTREFLKSLRKPFGDFMEPKFEFAVKFNALELDDS DLAIFIAVIILSGDRPGLLNVKPIEDIQDNLLQALELQLK LNHPESSQLFAKLLQKMTDLRQIVTEHVQLLQVLHPLLQE IYK Description Functional site 1) chain B residue 285 type sequence C description BINDING SITE FOR RESIDUE KNA B 501 source : AC5 2) chain B residue 288 type sequence R description BINDING SITE FOR RESIDUE KNA B 501 source : AC5 3) chain B residue 289 type sequence S description BINDING SITE FOR RESIDUE KNA B 501 source : AC5 4) chain B residue 292 type sequence A description BINDING SITE FOR RESIDUE KNA B 501 source : AC5 5) chain B residue 326 type sequence I description BINDING SITE FOR RESIDUE KNA B 501 source : AC5 6) chain B residue 327 type sequence Y description BINDING SITE FOR RESIDUE KNA B 501 source : AC5 7) chain B residue 364 type sequence M description BINDING SITE FOR RESIDUE KNA B 501 source : AC5 8) chain B residue 449 type sequence H description BINDING SITE FOR RESIDUE KNA B 501 source : AC5 9) chain B residue 259 type sequence E description BINDING SITE FOR RESIDUE TCE B 502 source : AC6 10) chain B residue 264 type sequence F description BINDING SITE FOR RESIDUE TCE B 502 source : AC6 11) chain B residue 266 type sequence H description BINDING SITE FOR RESIDUE TCE B 502 source : AC6 12) chain B residue 285 type sequence C description BINDING SITE FOR RESIDUE TCE B 502 source : AC6 13) chain B residue 341 type sequence I description BINDING SITE FOR RESIDUE TCE B 502 source : AC6 14) chain B residue 342 type sequence S description BINDING SITE FOR RESIDUE TCE B 502 source : AC6 15) chain B residue 312 type sequence N description BINDING SITE FOR RESIDUE GOL B 503 source : AC7 16) chain B residue 227 type sequence P description BINDING SITE FOR RESIDUE GOL B 504 source : AC8 17) chain B residue 228 type sequence L description BINDING SITE FOR RESIDUE GOL B 504 source : AC8 18) chain B residue 288 type sequence R description BINDING SITE FOR RESIDUE GOL B 504 source : AC8 19) chain B residue 295 type sequence E description BINDING SITE FOR RESIDUE GOL B 504 source : AC8 20) chain B residue 329 type sequence M description BINDING SITE FOR RESIDUE GOL B 504 source : AC8 21) chain B residue 333 type sequence L description BINDING SITE FOR RESIDUE GOL B 504 source : AC8 22) chain B residue 286 type BINDING sequence Q description BINDING => ECO:0000269|PubMed:9744270, ECO:0007744|PDB:2PRG source Swiss-Prot : SWS_FT_FI1 23) chain B residue 323 type BINDING sequence H description BINDING => ECO:0000269|PubMed:9744270, ECO:0007744|PDB:2PRG source Swiss-Prot : SWS_FT_FI1 24) chain B residue 449 type BINDING sequence H description BINDING => ECO:0000269|PubMed:9744270, ECO:0007744|PDB:2PRG source Swiss-Prot : SWS_FT_FI1 25) chain B residue 473 type BINDING sequence Y description BINDING => ECO:0000269|PubMed:9744270, ECO:0007744|PDB:2PRG source Swiss-Prot : SWS_FT_FI1 26) chain B residue 224 type CROSSLNK sequence K description Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:36737649 source Swiss-Prot : SWS_FT_FI2

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