|
eF-site ID
|
4ej1-D |
PDB Code
|
4ej1 |
Chain
|
D |
|
click to enlarge
|
|
Title
|
Binding of Nb113 camelid antibody fragment with the binary DHFR:folate complex |
Classification
|
Oxidoreductase/Immune system |
Compound
|
Dihydrofolate reductase |
Source
|
Escherichia coli (strain K12) (4EJ1) |
|
Sequence
|
D: |
QLQESGGGLVQAGGSLRLSCTASGRTFSSYAMGWFRQTPG
KEREFVAAITWGGSTTLYADSVKGRFTMSRDNAKNTVYLQ
MNSLKPEDTAVYYCAADGSQYRSTYSFRDKPDYGSWGQGT
QVTVSS
|
|
Description
|
(1) |
Dihydrofolate reductase (E.C.1.5.1.3), Nb113 camelid antibody fragment
|
|
Functional site
|
|
1)
|
chain |
D |
residue |
27 |
type |
|
sequence |
R
|
description |
BINDING SITE FOR RESIDUE PO4 B 203
|
source |
: AC7
|
|
2)
|
chain |
D |
residue |
76 |
type |
|
sequence |
K
|
description |
BINDING SITE FOR RESIDUE PO4 B 204
|
source |
: AC8
|
|
|
|