eF-site ID 4ect-A PDB Code 4ect Chain A click to enlarge Title Human DNA polymerase eta - DNA ternary complex: Reaction in the AT crystal at pH 7.0 for 140 sec Classification TRANSFERASE/DNA Compound DNA polymerase eta Source Homo sapiens (Human) (4ECT) Sequence A:  GPHMATGQDRVVALVDMDCFFVQVEQRQNPHLRNKPCAVV QYKSWKGGGIIAVSYEARAFGVTRSMWADDAKKLCPDLLL AQVRESRGKANLTKYREASVEVMEIMSRFAVIERASIDEA YVDLTSAVQERLQKLQGQPISADLLPSTYIEGLPQGPTVQ KEGMRKQGLFQWLDSLQIDNLTSPDLQLTVGAVIVEEMRA AIERETGFQCSAGISHNKVLAKLACGLNKPNRQTLVSHGS VPQLFSQMPIRKIRSLGGKLGASVIEILGIEYMGELTQFT ESQLQSHFGEKNGSWLYAMCRGIEHDPVKPRQLPKTIGCS KNFPGKTALATREQVQWWLLQLAQELEERLTKDRNDNDRV ATQLVVSIRVQGDKRLSSLRRCCALTRYDAHKMSHDAFTV IKNCNTSGIQTEWSPPLTMLFLCATKFSAS Description Functional site 1) chain A residue 13 type sequence D description BINDING SITE FOR RESIDUE MG A 501 source : AC1 2) chain A residue 115 type sequence D description BINDING SITE FOR RESIDUE MG A 501 source : AC1 3) chain A residue 116 type sequence E description BINDING SITE FOR RESIDUE MG A 501 source : AC1 4) chain A residue 13 type sequence D description BINDING SITE FOR RESIDUE CA A 502 source : AC2 5) chain A residue 14 type sequence M description BINDING SITE FOR RESIDUE CA A 502 source : AC2 6) chain A residue 115 type sequence D description BINDING SITE FOR RESIDUE CA A 502 source : AC2 7) chain A residue 13 type sequence D description BINDING SITE FOR RESIDUE MG A 503 source : AC3 8) chain A residue 14 type sequence M description BINDING SITE FOR RESIDUE MG A 503 source : AC3 9) chain A residue 115 type sequence D description BINDING SITE FOR RESIDUE MG A 503 source : AC3 10) chain A residue 13 type sequence D description BINDING SITE FOR RESIDUE DTP P 504 source : AC4 11) chain A residue 14 type sequence M description BINDING SITE FOR RESIDUE DTP P 504 source : AC4 12) chain A residue 15 type sequence D description BINDING SITE FOR RESIDUE DTP P 504 source : AC4 13) chain A residue 16 type sequence C description BINDING SITE FOR RESIDUE DTP P 504 source : AC4 14) chain A residue 17 type sequence F description BINDING SITE FOR RESIDUE DTP P 504 source : AC4 15) chain A residue 18 type sequence F description BINDING SITE FOR RESIDUE DTP P 504 source : AC4 16) chain A residue 48 type sequence I description BINDING SITE FOR RESIDUE DTP P 504 source : AC4 17) chain A residue 49 type sequence A description BINDING SITE FOR RESIDUE DTP P 504 source : AC4 18) chain A residue 52 type sequence Y description BINDING SITE FOR RESIDUE DTP P 504 source : AC4 19) chain A residue 55 type sequence R description BINDING SITE FOR RESIDUE DTP P 504 source : AC4 20) chain A residue 61 type sequence R description BINDING SITE FOR RESIDUE DTP P 504 source : AC4 21) chain A residue 115 type sequence D description BINDING SITE FOR RESIDUE DTP P 504 source : AC4 22) chain A residue 231 type sequence K description BINDING SITE FOR RESIDUE DTP P 504 source : AC4 23) chain A residue 13 type sequence D description BINDING SITE FOR RESIDUE DPO P 505 source : AC5 24) chain A residue 14 type sequence M description BINDING SITE FOR RESIDUE DPO P 505 source : AC5 25) chain A residue 15 type sequence D description BINDING SITE FOR RESIDUE DPO P 505 source : AC5 26) chain A residue 16 type sequence C description BINDING SITE FOR RESIDUE DPO P 505 source : AC5 27) chain A residue 17 type sequence F description BINDING SITE FOR RESIDUE DPO P 505 source : AC5 28) chain A residue 52 type sequence Y description BINDING SITE FOR RESIDUE DPO P 505 source : AC5 29) chain A residue 55 type sequence R description BINDING SITE FOR RESIDUE DPO P 505 source : AC5 30) chain A residue 61 type sequence R description BINDING SITE FOR RESIDUE DPO P 505 source : AC5 31) chain A residue 115 type sequence D description BINDING SITE FOR RESIDUE DPO P 505 source : AC5 32) chain A residue 231 type sequence K description BINDING SITE FOR RESIDUE DPO P 505 source : AC5 33) chain A residue 61 type sequence R description BINDING SITE FOR RESIDUE MG P 506 source : AC6 34) chain A residue 24 type sequence R description BINDING SITE FOR RESIDUE GOL A 507 source : AC7 35) chain A residue 244 type sequence P description BINDING SITE FOR RESIDUE GOL A 507 source : AC7 36) chain A residue 248 type sequence S description BINDING SITE FOR RESIDUE GOL A 507 source : AC7 37) chain A residue 276 type sequence G description BINDING SITE FOR RESIDUE GOL A 507 source : AC7 38) chain A residue 94 type sequence E description BINDING SITE FOR RESIDUE GOL A 508 source : AC8 39) chain A residue 95 type sequence A description BINDING SITE FOR RESIDUE GOL A 508 source : AC8 40) chain A residue 98 type sequence E description BINDING SITE FOR RESIDUE GOL A 508 source : AC8 41) chain A residue 303 type sequence R description BINDING SITE FOR RESIDUE GOL A 508 source : AC8 42) chain A residue 26 type sequence N description BINDING SITE FOR RESIDUE GOL A 509 source : AC9 43) chain A residue 27 type sequence P description BINDING SITE FOR RESIDUE GOL A 509 source : AC9 44) chain A residue 28 type sequence H description BINDING SITE FOR RESIDUE GOL A 509 source : AC9 45) chain A residue 271 type sequence G description BINDING SITE FOR RESIDUE GOL A 509 source : AC9 46) chain A residue 273 type sequence E description BINDING SITE FOR RESIDUE GOL A 509 source : AC9 47) chain A residue 274 type sequence Y description BINDING SITE FOR RESIDUE GOL A 509 source : AC9 48) chain A residue 277 type sequence E description BINDING SITE FOR RESIDUE GOL A 509 source : AC9 49) chain A residue 13 type BINDING sequence D description BINDING => ECO:0000269|PubMed:27284197, ECO:0007744|PDB:5KFO source Swiss-Prot : SWS_FT_FI1 50) chain A residue 14 type BINDING sequence M description BINDING => ECO:0000269|PubMed:27284197, ECO:0007744|PDB:5KFO source Swiss-Prot : SWS_FT_FI1 51) chain A residue 115 type BINDING sequence D description BINDING => ECO:0000269|PubMed:27284197, ECO:0007744|PDB:5KFO source Swiss-Prot : SWS_FT_FI1 52) chain A residue 116 type BINDING sequence E description BINDING => ECO:0000269|PubMed:27284197, ECO:0007744|PDB:5KFO source Swiss-Prot : SWS_FT_FI1 53) chain A residue 61 type BINDING sequence R description BINDING => ECO:0000269|PubMed:27284197 source Swiss-Prot : SWS_FT_FI2

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