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eF-site ID
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4e0s-A |
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PDB Code
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4e0s |
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Chain
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A |
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click to enlarge
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Title
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Crystal Structure of C5b-6 |
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Classification
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IMMUNE SYSTEM |
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Compound
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Complement C5 |
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Source
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ORGANISM_COMMON: human; ORGANISM_SCIENTIFIC: Homo sapiens; |
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Sequence
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A: |
EQTYVISAPKIFRVGASENIVIQVYGYTEAFDATISIKSY
PDKKFSYSSGHVHLSSENKFQNSAILTIQPKQLPGGQNPV
SYVYLEVVSKHFSKSKRMPITYDNGFLFIHTDKPVYTPDQ
SVKVRVYSLNDDLKPAKRETVLTFIDPEGSEVDMVEEIDH
IGIISFPDFKIPSNPRYGMWTIKAKYKEDFSTTGTAYFEV
KEYVLPHFSVSIEPEYNFIGYKNFKNFEITIKARYFYNKV
VTEADVYITFGIREDLKDDQKEMMQTAMQNTMLINGIAQV
TFDSETAVKELSYYSLEDLNNKYLYIAVTVIESTGGFSEE
AEIPGIKYVLSPYKLNLVATPLFLKPGIPYPIKVQVKDSL
DQLVGGVPVTLNAQTIDVNQETSDLDPSKSVTRVDDGVAS
FVLNLPSGVTVLEFNVKTDAPDLPEENQAREGYRAIAYSS
LSQSYLYIDWTDNHKALLVGEHLNIIVTPKSPYIDKITHY
NYLILSKGKIIHFGTREKFSDASYQSINIPVTQNMVPSSR
LLVYYIVTGEQTAELVSDSVWLNIEEKCGNQLQVHLSPDA
DAYSPGQTVSLNMATGMDSWVALAAVDSAVYGVQRGAKKP
LERVFQFLEKSDLGCGAGGGLNNANVFHLAGLTFLTNANA
DDSQENDEPCKEILRPRSKPEIRSYFPESWLWEVHLVPRR
KQLQFALPDSLTTWEIQGIGISNTGICVADTVKAKVFKDV
FLEMNIPYSVVRGEQIQLKGTVYNYRTSGMQFCVKMSAVE
GICTSESKCVRQKVEGSSSHLVTFTVLPLEIGLHNINFSL
ETWFGKEILVKTLRVVPEGVKRESYSGVTLDPRGIYGTIS
RRKEFPYRIPLDLVPKTEIKRILSVKGLLVGEILSAVLSQ
EGINILTHLPKGSAEAELMSVVPVFYVFHYLETGNHWNIF
HSDPLIEKQKLKKKLKEGMLSIMSYRNADYSYSVWKGGSA
STWLTAFALRVLGQVNKYVEQNQNSICNSLLWLVENYQLD
NGSFKENSQYQPIKLQGTLPVEARENSLYLTAFTVIGIRK
AFDICPLVKIDTALIKADNFLLENTLPAQSTFTLAISAYA
LSLGDKTHPQFRSIVSALKREALVKGNPPIYRFWKDNLQH
KDSSVPNTGTARMVETTAYALLTSLNLKDINYVNPVIKWL
SEEQRYGGGFYSTQDTINAIEGLTEYSLLVKQLRLSMDID
VSYKHKGALHNYKMTDKNFLGRPVEVLLNDDLIVSTGFGS
GLATVHVTTVVHKTSTSEEVCSFYLKIDTQDIEDYKRIVA
CASYKPSREESSSGSSHAVMDISLPTGISANEEDLKALVE
GVDQLFTDYQIKDGHVILQLNSIPSSDFLCVRFRIFELFE
VGFLSPATFTVYEYHRPDKQCTMFYSTSNIKIQKVCEGAA
CKCVEADCGQMQEELDLTISAETRKQTACKPEIAYAYKVS
ITSITVENVFVKYKATLLDIYKTGEAVAEKDSEITFIKKV
TCTNAELVKGRQYLIMGKEALQIKYNFSFRYIYPLDSLTW
IEYWPRDTTCSSCQAFLANLDEFAEDIFLNGC
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Description
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