eF-site ID 4e02-A PDB Code 4e02 Chain A click to enlarge Title Crystal structure of branched-chain alpha-ketoacid dehydrogenase kinase/(S)-2-chloro-3-phenylpropanoic acid complex with AMPPNP Classification TRANSFERASE/TRANSFERASE INHIBITOR Compound [3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial Source Rattus norvegicus (Rat) (BCKD_RAT) Sequence A:  LTPTMMLYSGRSQDGSHLLKSGRYLQQELPVRIAHRIKGF RSLPFIIGCNPTILHVHELYIRAFQKLTDFPPIKDQADEA QYCQLVRQLLDDHKDVVTLLAEGLRESRKHIEDEKLVRYF LDKTLTSRLGIRMLATHHLALHEDKPDFVGIICTRLSPKK IIEKWVDFARRLCEHKYGNAPRVRINGHVAARFPFIPMPL DYILPELLKNAMRATMESHLDTPYNVPDVVITIANNDVDL IIRISDRGGGIAHKDLDRVMDYHFTTAGFGFGLPTSRAYA EYLGGSLQLQSLQGIGTDVYLRLRHID Description Functional site 1) chain A residue 245 type sequence E description BINDING SITE FOR RESIDUE ANP A 401 source : AC1 2) chain A residue 249 type sequence N description BINDING SITE FOR RESIDUE ANP A 401 source : AC1 3) chain A residue 252 type sequence R description BINDING SITE FOR RESIDUE ANP A 401 source : AC1 4) chain A residue 253 type sequence A description BINDING SITE FOR RESIDUE ANP A 401 source : AC1 5) chain A residue 285 type sequence D description BINDING SITE FOR RESIDUE ANP A 401 source : AC1 6) chain A residue 289 type sequence G description BINDING SITE FOR RESIDUE ANP A 401 source : AC1 7) chain A residue 290 type sequence I description BINDING SITE FOR RESIDUE ANP A 401 source : AC1 8) chain A residue 298 type sequence V description BINDING SITE FOR RESIDUE ANP A 401 source : AC1 9) chain A residue 304 type sequence T description BINDING SITE FOR RESIDUE ANP A 401 source : AC1 10) chain A residue 305 type sequence T description BINDING SITE FOR RESIDUE ANP A 401 source : AC1 11) chain A residue 336 type sequence F description BINDING SITE FOR RESIDUE ANP A 401 source : AC1 12) chain A residue 337 type sequence G description BINDING SITE FOR RESIDUE ANP A 401 source : AC1 13) chain A residue 338 type sequence F description BINDING SITE FOR RESIDUE ANP A 401 source : AC1 14) chain A residue 339 type sequence G description BINDING SITE FOR RESIDUE ANP A 401 source : AC1 15) chain A residue 340 type sequence L description BINDING SITE FOR RESIDUE ANP A 401 source : AC1 16) chain A residue 341 type sequence P description BINDING SITE FOR RESIDUE ANP A 401 source : AC1 17) chain A residue 364 type sequence T description BINDING SITE FOR RESIDUE ANP A 401 source : AC1 18) chain A residue 298 type sequence V description BINDING SITE FOR RESIDUE K A 402 source : AC2 19) chain A residue 300 type sequence D description BINDING SITE FOR RESIDUE K A 402 source : AC2 20) chain A residue 303 type sequence F description BINDING SITE FOR RESIDUE K A 402 source : AC2 21) chain A residue 337 type sequence G description BINDING SITE FOR RESIDUE K A 402 source : AC2 22) chain A residue 341 type sequence P description BINDING SITE FOR RESIDUE K A 402 source : AC2 23) chain A residue 99 type sequence Y description BINDING SITE FOR RESIDUE WJ1 A 403 source : AC3 24) chain A residue 132 type sequence H description BINDING SITE FOR RESIDUE WJ1 A 403 source : AC3 25) chain A residue 167 type sequence R description BINDING SITE FOR RESIDUE WJ1 A 403 source : AC3 26) chain A residue 170 type sequence I description BINDING SITE FOR RESIDUE WJ1 A 403 source : AC3 27) chain A residue 171 type sequence R description BINDING SITE FOR RESIDUE WJ1 A 403 source : AC3 28) chain A residue 249 type sequence N description BINDING SITE FOR RESIDUE MG A 404 source : AC4 29) chain A residue 249 type BINDING sequence N description BINDING => ECO:0000269|PubMed:11562470, ECO:0007744|PDB:1GKZ source Swiss-Prot : SWS_FT_FI1 30) chain A residue 340 type BINDING sequence L description BINDING => ECO:0000269|PubMed:11562470, ECO:0007744|PDB:1GKZ source Swiss-Prot : SWS_FT_FI1 31) chain A residue 285 type BINDING sequence D description BINDING => ECO:0000269|PubMed:11562470, ECO:0007744|PDB:1GKZ source Swiss-Prot : SWS_FT_FI1 32) chain A residue 298 type BINDING sequence V description BINDING => ECO:0000269|PubMed:11562470, ECO:0007744|PDB:1GKZ source Swiss-Prot : SWS_FT_FI1 33) chain A residue 300 type BINDING sequence D description BINDING => ECO:0000269|PubMed:11562470, ECO:0007744|PDB:1GKZ source Swiss-Prot : SWS_FT_FI1 34) chain A residue 303 type BINDING sequence F description BINDING => ECO:0000269|PubMed:11562470, ECO:0007744|PDB:1GKZ source Swiss-Prot : SWS_FT_FI1 35) chain A residue 304 type BINDING sequence T description BINDING => ECO:0000269|PubMed:11562470, ECO:0007744|PDB:1GKZ source Swiss-Prot : SWS_FT_FI1 36) chain A residue 305 type BINDING sequence T description BINDING => ECO:0000269|PubMed:11562470, ECO:0007744|PDB:1GKZ source Swiss-Prot : SWS_FT_FI1 37) chain A residue 337 type BINDING sequence G description BINDING => ECO:0000269|PubMed:11562470, ECO:0007744|PDB:1GKZ source Swiss-Prot : SWS_FT_FI1 38) chain A residue 162 type MOD_RES sequence K description N6-acetyllysine => ECO:0000250|UniProtKB:O14874 source Swiss-Prot : SWS_FT_FI3 39) chain A residue 203 type MOD_RES sequence K description N6-acetyllysine => ECO:0000250|UniProtKB:O14874 source Swiss-Prot : SWS_FT_FI3

Display surface Download Links