eF-site ID 4dvl-B
PDB Code 4dvl
Chain B

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Title Crystal structure of the glycoprotein Erns from the pestivirus BVDV-1 in complex with 2'-3'-cyclo-UMP
Classification VIRAL PROTEIN
Compound E(rns) glycoprotein
Source (POLG_BVDVC)
Sequence B:  ENITQWNLQDNGTEGIQRAMFQRGVNRSLHGIWPEKICTG
VPSHLATDTELKAIHGMMDASEKTNYTCCRLQRHEWNKHG
WCNWYNIEPWILLMNKTQANLTEGQPLRECAVTCRYDRDS
DLNVVTQARDSPTPLTGCKKGKNFSFAGILVQGPCNFEIA
V
Description


Functional site

1) chain B
residue 76
type ACT_SITE
sequence H
description For E(rns) glycoprotein RNase activity => ECO:0000269|PubMed:22579253
source Swiss-Prot : SWS_FT_FI1

2) chain B
residue 77
type ACT_SITE
sequence E
description For E(rns) glycoprotein RNase activity => ECO:0000269|PubMed:22579253
source Swiss-Prot : SWS_FT_FI1

3) chain B
residue 80
type ACT_SITE
sequence K
description For E(rns) glycoprotein RNase activity => ECO:0000269|PubMed:22579253
source Swiss-Prot : SWS_FT_FI1

4) chain B
residue 81
type ACT_SITE
sequence H
description For E(rns) glycoprotein RNase activity => ECO:0000269|PubMed:22579253
source Swiss-Prot : SWS_FT_FI1

5) chain B
residue 32
type SITE
sequence H
description Hydrogen donor to release the cleavage products of E(rns) glycoprotein RNase activity
source Swiss-Prot : SWS_FT_FI2

6) chain B
residue 67
type CARBOHYD
sequence N
description N-linked (GlcNAc...) asparagine; by host => ECO:0000269|PubMed:22579253
source Swiss-Prot : SWS_FT_FI3

7) chain B
residue 97
type CARBOHYD
sequence N
description N-linked (GlcNAc...) asparagine; by host => ECO:0000269|PubMed:22579253
source Swiss-Prot : SWS_FT_FI3

8) chain B
residue 102
type CARBOHYD
sequence N
description N-linked (GlcNAc...) asparagine; by host => ECO:0000269|PubMed:22579253
source Swiss-Prot : SWS_FT_FI3

9) chain B
residue 4
type CARBOHYD
sequence N
description N-linked (GlcNAc...) asparagine; by host => ECO:0000269|PubMed:22579253
source Swiss-Prot : SWS_FT_FI3

10) chain B
residue 13
type CARBOHYD
sequence N
description N-linked (GlcNAc...) asparagine; by host => ECO:0000269|PubMed:22579253
source Swiss-Prot : SWS_FT_FI3

11) chain B
residue 28
type CARBOHYD
sequence N
description N-linked (GlcNAc...) asparagine; by host => ECO:0000269|PubMed:22579253
source Swiss-Prot : SWS_FT_FI3

12) chain B
residue 145
type CARBOHYD
sequence N
description N-linked (GlcNAc...) asparagine; by host => ECO:0000255
source Swiss-Prot : SWS_FT_FI4


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