eF-site ID 4dlg-A PDB Code 4dlg Chain A click to enlarge Title Ternary Structure of the large Fragment of Taq DNA polymerase Classification Transferase/DNA Compound DNA polymerase I, thermostable Source Thermus aquaticus (4DLG) Sequence A:  ALEEAPWPPPEGAFVGFVLSRKEPMWADLLALAAARGGRV HRAPEPYKALRDLKEARGLLAKDLSVLALREGLGLPPGDD PMLLAYLLDPSNTTPEGVARRYGGEWTEEAGERAALSERL FANLWGRLEGEERLLWLYREVERPLSAVLAHMEATGVRLD VAYLRALSLEVAEEIARLEAEVFRLAGHPFNLNSRDQLER VLFDELGLPAIGKTEKTGKRSTSAAVLEALREAHPIVEKI LQYRELTKLKSTYIDPLPDLIHPRTGRLHTRFNQTATATG RLSSSDPNLQNIPVRTPLGQRIRRAFIAEEGWLLVALDYS QIELRVLAHLSGDENLIRVFQEGRDIHTETASWMFGVPRE AVDPLMRRAAKTINFGVLYGMSAHRLSQELAIPYEEAQAF IERYFQSFPKVRAWIEKTLEEGRRRGYVETLFGRRRYVPD LEARVKSVREAAERMAFNMPVQGTAADLMKLAMVKLFPRL EEMGARMLLQVHDELVLEAPKERAEAVARLAKEVMEGVYP LAVPLEVEVGIGEDWLSAKE Description Functional site 1) chain A residue 573 type sequence R description BINDING SITE FOR RESIDUE DCT A 901 source : AC1 2) chain A residue 610 type sequence D description BINDING SITE FOR RESIDUE DCT A 901 source : AC1 3) chain A residue 611 type sequence Y description BINDING SITE FOR RESIDUE DCT A 901 source : AC1 4) chain A residue 612 type sequence S description BINDING SITE FOR RESIDUE DCT A 901 source : AC1 5) chain A residue 613 type sequence Q description BINDING SITE FOR RESIDUE DCT A 901 source : AC1 6) chain A residue 614 type sequence I description BINDING SITE FOR RESIDUE DCT A 901 source : AC1 7) chain A residue 615 type sequence E description BINDING SITE FOR RESIDUE DCT A 901 source : AC1 8) chain A residue 639 type sequence H description BINDING SITE FOR RESIDUE DCT A 901 source : AC1 9) chain A residue 659 type sequence R description BINDING SITE FOR RESIDUE DCT A 901 source : AC1 10) chain A residue 663 type sequence K description BINDING SITE FOR RESIDUE DCT A 901 source : AC1 11) chain A residue 667 type sequence F description BINDING SITE FOR RESIDUE DCT A 901 source : AC1 12) chain A residue 785 type sequence D description BINDING SITE FOR RESIDUE DCT A 901 source : AC1 13) chain A residue 610 type sequence D description BINDING SITE FOR RESIDUE MG A 902 source : AC2 14) chain A residue 611 type sequence Y description BINDING SITE FOR RESIDUE MG A 902 source : AC2 15) chain A residue 785 type sequence D description BINDING SITE FOR RESIDUE MG A 902 source : AC2 16) chain A residue 610 type sequence D description BINDING SITE FOR RESIDUE MG A 903 source : AC3 17) chain A residue 785 type sequence D description BINDING SITE FOR RESIDUE MG A 903 source : AC3 18) chain A residue 786 type sequence E description BINDING SITE FOR RESIDUE MG A 903 source : AC3 19) chain A residue 309 type sequence F description BINDING SITE FOR RESIDUE ACT A 904 source : AC4 20) chain A residue 311 type sequence L description BINDING SITE FOR RESIDUE ACT A 904 source : AC4 21) chain A residue 405 type sequence R description BINDING SITE FOR RESIDUE ACT A 904 source : AC4 22) chain A residue 417 type sequence W description BINDING SITE FOR RESIDUE ACT A 905 source : AC5 23) chain A residue 431 type sequence R description BINDING SITE FOR RESIDUE ACT A 905 source : AC5 24) chain A residue 435 type sequence R description BINDING SITE FOR RESIDUE ACT A 905 source : AC5 25) chain A residue 455 type sequence Y description BINDING SITE FOR RESIDUE ACT A 906 source : AC6 26) chain A residue 455 type sequence Y description BINDING SITE FOR RESIDUE ACT A 906 source : AC6 27) chain A residue 485 type sequence N description BINDING SITE FOR RESIDUE GOL A 907 source : AC7 28) chain A residue 486 type sequence S description BINDING SITE FOR RESIDUE GOL A 907 source : AC7 29) chain A residue 487 type sequence R description BINDING SITE FOR RESIDUE GOL A 907 source : AC7 30) chain A residue 488 type sequence D description BINDING SITE FOR RESIDUE GOL A 907 source : AC7 31) chain A residue 578 type sequence D description BINDING SITE FOR RESIDUE GOL C 302 source : AC9 32) chain A residue 579 type sequence P description BINDING SITE FOR RESIDUE GOL C 302 source : AC9 33) chain A residue 659-678 type prosite sequence RRAAKTINFGVLYGMSAHRL description DNA_POLYMERASE_A DNA polymerase family A signature. RraAKtinFGvlYgmSahrL source prosite : PS00447

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