|
eF-site ID
|
4dhz-F |
PDB Code
|
4dhz |
Chain
|
F |
|
click to enlarge
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Title
|
The structure of h/ceOTUB1-ubiquitin aldehyde-UBC13~Ub |
Classification
|
HYDROLASE/SIGNALING PROTEIN/LIGASE |
Compound
|
Ubiquitin thioesterase otubain-like |
Source
|
Caenorhabditis elegans (UBE2N_HUMAN) |
|
Sequence
|
F: |
GLPRRIIKETQRLLAEPVPGIKAEPDESNARYFHVVIAGP
QDSPFEGGTFKLELFLPEEYPMAAPKVRFMTKIYHPNVDK
LGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPDDPLA
NDVAEQWKTNEAQAIETARAWTRLYAMNN
|
|
Description
|
(1) |
Ubiquitin thioesterase otubain-like (E.C.3.4.19.12), Ubiquitin aldehyde, Ubiquitin-conjugating enzyme E2 N (E.C.6.3.2.19)
|
|
Functional site
|
|
1)
|
chain |
F |
residue |
87 |
type |
ACT_SITE |
sequence |
C
|
description |
Glycyl thioester intermediate => ECO:0000255|PROSITE-ProRule:PRU00388
|
source |
Swiss-Prot : SWS_FT_FI1
|
|
2)
|
chain |
F |
residue |
82 |
type |
MOD_RES |
sequence |
K
|
description |
N6-acetyllysine => ECO:0007744|PubMed:19608861
|
source |
Swiss-Prot : SWS_FT_FI2
|
|
3)
|
chain |
F |
residue |
92 |
type |
CROSSLNK |
sequence |
K
|
description |
Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ISG15) => ECO:0000269|PubMed:16112642, ECO:0000269|PubMed:16122702
|
source |
Swiss-Prot : SWS_FT_FI3
|
|
4)
|
chain |
F |
residue |
76-91 |
type |
prosite |
sequence |
YHPNVDKLGRICLDIL
|
description |
UBC_1 Ubiquitin-conjugating (UBC) active site signature. YHPNVdkl.GrICLdiL
|
source |
prosite : PS00183
|
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