eF-site ID 4dhz-F
PDB Code 4dhz
Chain F

click to enlarge
Title The structure of h/ceOTUB1-ubiquitin aldehyde-UBC13~Ub
Classification HYDROLASE/SIGNALING PROTEIN/LIGASE
Compound Ubiquitin thioesterase otubain-like
Source Caenorhabditis elegans (UBE2N_HUMAN)
Sequence F:  GLPRRIIKETQRLLAEPVPGIKAEPDESNARYFHVVIAGP
QDSPFEGGTFKLELFLPEEYPMAAPKVRFMTKIYHPNVDK
LGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPDDPLA
NDVAEQWKTNEAQAIETARAWTRLYAMNN
Description (1)  Ubiquitin thioesterase otubain-like (E.C.3.4.19.12), Ubiquitin aldehyde, Ubiquitin-conjugating enzyme E2 N (E.C.6.3.2.19)


Functional site

1) chain F
residue 87
type ACT_SITE
sequence C
description Glycyl thioester intermediate => ECO:0000255|PROSITE-ProRule:PRU00388
source Swiss-Prot : SWS_FT_FI1

2) chain F
residue 82
type MOD_RES
sequence K
description N6-acetyllysine => ECO:0007744|PubMed:19608861
source Swiss-Prot : SWS_FT_FI2

3) chain F
residue 92
type CROSSLNK
sequence K
description Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ISG15) => ECO:0000269|PubMed:16112642, ECO:0000269|PubMed:16122702
source Swiss-Prot : SWS_FT_FI3

4) chain F
residue 76-91
type prosite
sequence YHPNVDKLGRICLDIL
description UBC_1 Ubiquitin-conjugating (UBC) active site signature. YHPNVdkl.GrICLdiL
source prosite : PS00183


Display surface

Download
Links