eF-site ID 4de7-A PDB Code 4de7 Chain A click to enlarge Title Crystal structure of glucosyl-3-phosphoglycerate synthase from Mycobacterium tuberculosis in complex with Mg2+ and uridine-diphosphate (UDP) Classification TRANSFERASE Compound GLUCOSYL-3-PHOSPHOGLYCERATE SYNTHASE (GpgS) Source Mycobacterium tuberculosis (O05309_MYCTU) Sequence A:  PLDTTWHRPGWTIGELEAAKAGRTISVVLPALNEEATIES VIDSISPLVDGLVDELIVLDSGSTDDTEIRAIASGARVVS REQALPEVPVRPGKGEALWRSLAATSGDIVVFIDSDLINP HPLFVPWLVGPLLTGEGIQLVKSFYRGGRVTELVARPLLA ALRPELGCVLQPLSGEYAASRELLTSLPFAPGYGVEIGLL IDTFDRLGLDAIAQVNLGVRAHRNRPLDELGAMSRQVIAT LLSRCGIPDSGVGLTQFLPGDYTRHTWPVSLVDRPPMKVM R Description Functional site 1) chain A residue 50 type sequence P description BINDING SITE FOR RESIDUE UDP A 401 source : AC1 2) chain A residue 51 type sequence A description BINDING SITE FOR RESIDUE UDP A 401 source : AC1 3) chain A residue 52 type sequence L description BINDING SITE FOR RESIDUE UDP A 401 source : AC1 4) chain A residue 54 type sequence E description BINDING SITE FOR RESIDUE UDP A 401 source : AC1 5) chain A residue 81 type sequence S description BINDING SITE FOR RESIDUE UDP A 401 source : AC1 6) chain A residue 114 type sequence K description BINDING SITE FOR RESIDUE UDP A 401 source : AC1 7) chain A residue 135 type sequence S description BINDING SITE FOR RESIDUE UDP A 401 source : AC1 8) chain A residue 136 type sequence D description BINDING SITE FOR RESIDUE UDP A 401 source : AC1 9) chain A residue 184 type sequence G description BINDING SITE FOR RESIDUE GOL A 402 source : AC2 10) chain A residue 187 type sequence T description BINDING SITE FOR RESIDUE GOL A 402 source : AC2 11) chain A residue 256 type sequence R description BINDING SITE FOR RESIDUE GOL A 402 source : AC2 12) chain A residue 258 type sequence H description BINDING SITE FOR RESIDUE GOL A 402 source : AC2 13) chain A residue 260 type sequence N description BINDING SITE FOR RESIDUE GOL A 402 source : AC2 14) chain A residue 97 type sequence R description BINDING SITE FOR RESIDUE GOL A 403 source : AC3 15) chain A residue 98 type sequence V description BINDING SITE FOR RESIDUE GOL A 403 source : AC3 16) chain A residue 103 type sequence Q description BINDING SITE FOR RESIDUE GOL A 403 source : AC3 17) chain A residue 114 type BINDING sequence K description BINDING => ECO:0000269|PubMed:26136334, ECO:0007744|PDB:4Y6N, ECO:0007744|PDB:4Y6U, ECO:0007744|PDB:4Y7F, ECO:0007744|PDB:4Y7G, ECO:0007744|PDB:4Y9X source Swiss-Prot : SWS_FT_FI1 18) chain A residue 134 type BINDING sequence D description BINDING => ECO:0000269|PubMed:26136334, ECO:0007744|PDB:4Y6N, ECO:0007744|PDB:4Y6U, ECO:0007744|PDB:4Y7F, ECO:0007744|PDB:4Y7G, ECO:0007744|PDB:4Y9X source Swiss-Prot : SWS_FT_FI1 19) chain A residue 136 type BINDING sequence D description BINDING => ECO:0000269|PubMed:26136334, ECO:0007744|PDB:4Y6N, ECO:0007744|PDB:4Y6U, ECO:0007744|PDB:4Y7F, ECO:0007744|PDB:4Y7G, ECO:0007744|PDB:4Y9X source Swiss-Prot : SWS_FT_FI1 20) chain A residue 229 type BINDING sequence Y description BINDING => ECO:0000269|PubMed:26136334, ECO:0007744|PDB:4Y6N, ECO:0007744|PDB:4Y6U, ECO:0007744|PDB:4Y7F, ECO:0007744|PDB:4Y7G, ECO:0007744|PDB:4Y9X source Swiss-Prot : SWS_FT_FI1 21) chain A residue 258 type BINDING sequence H description BINDING => ECO:0000269|PubMed:26136334, ECO:0007744|PDB:4Y6N, ECO:0007744|PDB:4Y6U, ECO:0007744|PDB:4Y7F, ECO:0007744|PDB:4Y7G, ECO:0007744|PDB:4Y9X source Swiss-Prot : SWS_FT_FI1 22) chain A residue 50 type BINDING sequence P description BINDING => ECO:0000269|PubMed:26136334, ECO:0007744|PDB:4Y6N, ECO:0007744|PDB:4Y6U, ECO:0007744|PDB:4Y7F, ECO:0007744|PDB:4Y7G, ECO:0007744|PDB:4Y9X source Swiss-Prot : SWS_FT_FI1 23) chain A residue 81 type BINDING sequence S description BINDING => ECO:0000269|PubMed:26136334, ECO:0007744|PDB:4Y6N, ECO:0007744|PDB:4Y6U, ECO:0007744|PDB:4Y7F, ECO:0007744|PDB:4Y7G, ECO:0007744|PDB:4Y9X source Swiss-Prot : SWS_FT_FI1 24) chain A residue 184 type BINDING sequence G description BINDING => ECO:0000269|PubMed:26136334, ECO:0000269|PubMed:28625787, ECO:0007744|PDB:4Y6N, ECO:0007744|PDB:4Y6U, ECO:0007744|PDB:4Y9X, ECO:0007744|PDB:5JQX source Swiss-Prot : SWS_FT_FI2 25) chain A residue 256 type BINDING sequence R description BINDING => ECO:0000269|PubMed:28625787, ECO:0007744|PDB:5JT0 source Swiss-Prot : SWS_FT_FI3 26) chain A residue 260 type BINDING sequence N description BINDING => ECO:0000269|PubMed:26136334, ECO:0007744|PDB:4Y6N, ECO:0007744|PDB:4Y6U source Swiss-Prot : SWS_FT_FI4

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