eF-site ID 4dc1-B PDB Code 4dc1 Chain B click to enlarge Title Crystal Structure of Y202F Actinorhodin Polyketide Ketoreductase with NADPH Classification OXIDOREDUCTASE Compound Ketoacyl reductase Source Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145) (ACT3_STRCO) Sequence B:  MATQDSEVALVTGATSGIGLEIARRLGKEGLRVFVCARGE EGLRTTLKELREAGVEADGRTCDVRSVPEIEALVAAVVER YGPVDVLVNNAGRPGGGATAELADELWLDVVETNLTGVFR VTKQVLKAGGMLERGTGRIVNIASTGGKQGVVHAAPYSAS KHGVVGFTKALGLELARTGITVNAVCPGFVETPMAASVRE HFSDIWEVSTEEAFDRITARVPIGRYVQPSEVAEMVAYLI GPGAAAVTAQALNVCGGLGNY Description Functional site 1) chain B residue 51 type sequence R description BINDING SITE FOR RESIDUE NDP A 301 source : AC1 2) chain B residue 13 type sequence G description BINDING SITE FOR RESIDUE NDP B 301 source : AC2 3) chain B residue 15 type sequence T description BINDING SITE FOR RESIDUE NDP B 301 source : AC2 4) chain B residue 16 type sequence S description BINDING SITE FOR RESIDUE NDP B 301 source : AC2 5) chain B residue 18 type sequence I description BINDING SITE FOR RESIDUE NDP B 301 source : AC2 6) chain B residue 37 type sequence A description BINDING SITE FOR RESIDUE NDP B 301 source : AC2 7) chain B residue 38 type sequence R description BINDING SITE FOR RESIDUE NDP B 301 source : AC2 8) chain B residue 39 type sequence G description BINDING SITE FOR RESIDUE NDP B 301 source : AC2 9) chain B residue 62 type sequence C description BINDING SITE FOR RESIDUE NDP B 301 source : AC2 10) chain B residue 63 type sequence D description BINDING SITE FOR RESIDUE NDP B 301 source : AC2 11) chain B residue 64 type sequence V description BINDING SITE FOR RESIDUE NDP B 301 source : AC2 12) chain B residue 90 type sequence N description BINDING SITE FOR RESIDUE NDP B 301 source : AC2 13) chain B residue 91 type sequence A description BINDING SITE FOR RESIDUE NDP B 301 source : AC2 14) chain B residue 92 type sequence G description BINDING SITE FOR RESIDUE NDP B 301 source : AC2 15) chain B residue 142 type sequence I description BINDING SITE FOR RESIDUE NDP B 301 source : AC2 16) chain B residue 143 type sequence A description BINDING SITE FOR RESIDUE NDP B 301 source : AC2 17) chain B residue 144 type sequence S description BINDING SITE FOR RESIDUE NDP B 301 source : AC2 18) chain B residue 157 type sequence Y description BINDING SITE FOR RESIDUE NDP B 301 source : AC2 19) chain B residue 161 type sequence K description BINDING SITE FOR RESIDUE NDP B 301 source : AC2 20) chain B residue 187 type sequence P description BINDING SITE FOR RESIDUE NDP B 301 source : AC2 21) chain B residue 188 type sequence G description BINDING SITE FOR RESIDUE NDP B 301 source : AC2 22) chain B residue 190 type sequence V description BINDING SITE FOR RESIDUE NDP B 301 source : AC2 23) chain B residue 192 type sequence T description BINDING SITE FOR RESIDUE NDP B 301 source : AC2 24) chain B residue 193 type sequence P description BINDING SITE FOR RESIDUE NDP B 301 source : AC2 25) chain B residue 194 type sequence M description BINDING SITE FOR RESIDUE NDP B 301 source : AC2 26) chain B residue 157 type ACT_SITE sequence Y description Proton acceptor => ECO:0000255|PROSITE-ProRule:PRU10001 source Swiss-Prot : SWS_FT_FI1 27) chain B residue 11 type BINDING sequence V description BINDING => ECO:0000269|PubMed:15458634, ECO:0000269|PubMed:15544323 source Swiss-Prot : SWS_FT_FI2 28) chain B residue 63 type BINDING sequence D description BINDING => ECO:0000269|PubMed:15458634, ECO:0000269|PubMed:15544323 source Swiss-Prot : SWS_FT_FI2 29) chain B residue 161 type BINDING sequence K description BINDING => ECO:0000269|PubMed:15458634, ECO:0000269|PubMed:15544323 source Swiss-Prot : SWS_FT_FI2 30) chain B residue 144 type BINDING sequence S description BINDING => ECO:0000250 source Swiss-Prot : SWS_FT_FI3

Display surface Download Links