eF-site ID 4dbp-A
PDB Code 4dbp
Chain A

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Title Myosin VI nucleotide-free (MDINSERT2) D179Y crystal structure
Classification motor protein/Calcium binding protein
Compound Myosin-VI
Source (CALM_DROME)
Sequence A:  DGKPVWAPHPTDGFQVGNIVDIGPDSLTIEPLNQKGKTFL
ALINQVFPAEEDSKKDVEDNCSLMYLNEATLLHNIKVRYS
KDRIYTYVANILIAVNPYFDIPKIYSSETIKSYQGKSLGT
MPPHVFAIADKAFRDMKVLKLSQSIIVSGESGAGKTENTK
FVLRYLTESYGTGQDIYDRIVEANPLLEAFGNAKTVRNNN
SSRFGKFVEIHFNEKSSVVGGFVSHYLLEKSRICVQGKEE
RNYHIFYRLCAGASEDIRERLHLSSPDNFRYLNRGCTRYF
ANKETDKQILQNRKSPEYLKAGSLKDPLLDDHGDFIRMCT
AMKKIGLDDEEKLDLFRVVAGVLHLGNIDFEEAGCNLKNK
STQALEYCAELLGLDQDDLRVSLTTRVMLTTAGGAKGTVI
KVPLKVEQANNARDALAKTVYSHLFDHVVNRVNQCFPFET
SSYFIGVLDIAGFEYFEHNSFEQFCINYCNEKLQQFFNER
ILKEEQELYQKEGLGVNEVHYVDNQDCIDLIEARLVGILD
ILDEENRLPQPSDQHFTSAVHQKHKDHFRLSIPRKSKLAI
HRNIRDDEGFIIRHFAGAVCYETTQFVEKNNDALHMSLES
LICESRDKFIRELFEFISVGNKFKTQLNLLLDKLRSTGAS
FIRCIKPNLKMTSHHFEGAQILSQLQCSGMVSVLDLMQGG
FPSRASFHELYNMYKKYMPDKLARLDPRLFCKALFKALGL
NEIDYKFGLTKVFFRPGKFAEFDQIMKSDPDHLAELVKRV
NHWLICSRWKKVQWCSLSVIKLKNKIKYRAE
Description


Functional site

1) chain A
residue 205
type
sequence R
description BINDING SITE FOR RESIDUE TBU A 901
source : AC1

2) chain A
residue 206
type
sequence F
description BINDING SITE FOR RESIDUE TBU A 901
source : AC1

3) chain A
residue 229
type
sequence L
description BINDING SITE FOR RESIDUE TBU A 901
source : AC1

4) chain A
residue 158
type
sequence T
description BINDING SITE FOR RESIDUE TBU A 902
source : AC2

5) chain A
residue 165
type
sequence L
description BINDING SITE FOR RESIDUE TBU A 902
source : AC2

6) chain A
residue 186
type
sequence N
description BINDING SITE FOR RESIDUE TBU A 902
source : AC2

7) chain A
residue 208
type
sequence K
description BINDING SITE FOR RESIDUE TBU A 902
source : AC2

8) chain A
residue 717
type
sequence M
description BINDING SITE FOR RESIDUE EDO A 903
source : AC3

9) chain A
residue 720
type
sequence K
description BINDING SITE FOR RESIDUE EDO A 903
source : AC3

10) chain A
residue 767
type
sequence D
description BINDING SITE FOR RESIDUE EDO A 903
source : AC3

11) chain A
residue 771
type
sequence K
description BINDING SITE FOR RESIDUE EDO A 903
source : AC3

12) chain A
residue 284
type
sequence N
description BINDING SITE FOR RESIDUE EDO A 904
source : AC4

13) chain A
residue 288
type
sequence D
description BINDING SITE FOR RESIDUE EDO A 904
source : AC4

14) chain A
residue 304
type
sequence G
description BINDING SITE FOR RESIDUE EDO A 904
source : AC4

15) chain A
residue 305
type
sequence S
description BINDING SITE FOR RESIDUE EDO A 904
source : AC4

16) chain A
residue 487
type
sequence R
description BINDING SITE FOR RESIDUE EDO A 905
source : AC5

17) chain A
residue 100
type
sequence Y
description BINDING SITE FOR RESIDUE EDO A 906
source : AC6

18) chain A
residue 670
type
sequence K
description BINDING SITE FOR RESIDUE EDO A 906
source : AC6

19) chain A
residue 673
type
sequence L
description BINDING SITE FOR RESIDUE EDO A 906
source : AC6

20) chain A
residue 550
type
sequence K
description BINDING SITE FOR RESIDUE EDO A 907
source : AC7

21) chain A
residue 551
type
sequence H
description BINDING SITE FOR RESIDUE EDO A 907
source : AC7

22) chain A
residue 553
type
sequence D
description BINDING SITE FOR RESIDUE EDO A 907
source : AC7

23) chain A
residue 554
type
sequence H
description BINDING SITE FOR RESIDUE EDO A 907
source : AC7

24) chain A
residue 7
type
sequence V
description BINDING SITE FOR RESIDUE EDO A 908
source : AC8

25) chain A
residue 50
type
sequence P
description BINDING SITE FOR RESIDUE EDO A 908
source : AC8

26) chain A
residue 142
type
sequence K
description BINDING SITE FOR RESIDUE EDO A 909
source : AC9

27) chain A
residue 143
type
sequence L
description BINDING SITE FOR RESIDUE EDO A 909
source : AC9

28) chain A
residue 144
type
sequence S
description BINDING SITE FOR RESIDUE EDO A 909
source : AC9

29) chain A
residue 449
type
sequence S
description BINDING SITE FOR RESIDUE EDO A 909
source : AC9

30) chain A
residue 556
type
sequence R
description BINDING SITE FOR RESIDUE EDO A 910
source : BC1

31) chain A
residue 581
type
sequence H
description BINDING SITE FOR RESIDUE EDO A 910
source : BC1

32) chain A
residue 582
type
sequence F
description BINDING SITE FOR RESIDUE EDO A 910
source : BC1

33) chain A
residue 50
type
sequence P
description BINDING SITE FOR RESIDUE EDO A 911
source : BC2

34) chain A
residue 68
type
sequence L
description BINDING SITE FOR RESIDUE EDO A 911
source : BC2

35) chain A
residue 69
type
sequence N
description BINDING SITE FOR RESIDUE EDO A 911
source : BC2

36) chain A
residue 761
type
sequence G
description BINDING SITE FOR RESIDUE EDO A 911
source : BC2

37) chain A
residue 253
type
sequence A
description BINDING SITE FOR RESIDUE EDO A 912
source : BC3

38) chain A
residue 254
type
sequence G
description BINDING SITE FOR RESIDUE EDO A 912
source : BC3

39) chain A
residue 255
type
sequence A
description BINDING SITE FOR RESIDUE EDO A 912
source : BC3

40) chain A
residue 290
type
sequence Q
description BINDING SITE FOR RESIDUE EDO A 912
source : BC3

41) chain A
residue 291
type
sequence I
description BINDING SITE FOR RESIDUE EDO A 912
source : BC3

42) chain A
residue 292
type
sequence L
description BINDING SITE FOR RESIDUE EDO A 912
source : BC3

43) chain A
residue 295
type
sequence R
description BINDING SITE FOR RESIDUE EDO A 912
source : BC3

44) chain A
residue 314
type
sequence H
description BINDING SITE FOR RESIDUE EDO A 912
source : BC3

45) chain A
residue 275
type
sequence N
description BINDING SITE FOR RESIDUE EDO A 913
source : BC4

46) chain A
residue 279
type
sequence T
description BINDING SITE FOR RESIDUE EDO A 913
source : BC4

47) chain A
residue 299
type
sequence E
description BINDING SITE FOR RESIDUE EDO A 913
source : BC4

48) chain A
residue 197
type
sequence T
description BINDING SITE FOR RESIDUE EDO A 914
source : BC5

49) chain A
residue 198
type
sequence V
description BINDING SITE FOR RESIDUE EDO A 914
source : BC5

50) chain A
residue 205
type
sequence R
description BINDING SITE FOR RESIDUE EDO A 914
source : BC5

51) chain A
residue 242
type
sequence E
description BINDING SITE FOR RESIDUE EDO A 914
source : BC5

52) chain A
residue 461
type
sequence E
description BINDING SITE FOR RESIDUE EDO A 914
source : BC5

53) chain A
residue 463
type
sequence F
description BINDING SITE FOR RESIDUE EDO A 914
source : BC5

54) chain A
residue 232
type
sequence K
description BINDING SITE FOR RESIDUE EDO A 915
source : BC6

55) chain A
residue 233
type
sequence S
description BINDING SITE FOR RESIDUE EDO A 915
source : BC6

56) chain A
residue 505
type
sequence E
description BINDING SITE FOR RESIDUE EDO A 916
source : BC7

57) chain A
residue 507
type
sequence H
description BINDING SITE FOR RESIDUE EDO A 916
source : BC7

58) chain A
residue 173
type
sequence G
description BINDING SITE FOR RESIDUE EDO A 917
source : BC8

59) chain A
residue 174
type
sequence T
description BINDING SITE FOR RESIDUE EDO A 917
source : BC8

60) chain A
residue 175
type
sequence G
description BINDING SITE FOR RESIDUE EDO A 917
source : BC8

61) chain A
residue 176
type
sequence Q
description BINDING SITE FOR RESIDUE EDO A 917
source : BC8

62) chain A
residue 177
type
sequence D
description BINDING SITE FOR RESIDUE EDO A 917
source : BC8

63) chain A
residue 178
type
sequence I
description BINDING SITE FOR RESIDUE EDO A 917
source : BC8

64) chain A
residue 220
type
sequence V
description BINDING SITE FOR RESIDUE EDO A 917
source : BC8

65) chain A
residue 231
type
sequence E
description BINDING SITE FOR RESIDUE EDO A 918
source : BC9

66) chain A
residue 233
type
sequence S
description BINDING SITE FOR RESIDUE EDO A 918
source : BC9

67) chain A
residue 234
type
sequence R
description BINDING SITE FOR RESIDUE EDO A 918
source : BC9

68) chain A
residue 237
type
sequence V
description BINDING SITE FOR RESIDUE EDO A 918
source : BC9

69) chain A
residue 498
type
sequence K
description BINDING SITE FOR RESIDUE EDO A 919
source : CC1

70) chain A
residue 49
type
sequence F
description BINDING SITE FOR RESIDUE EDO A 920
source : CC2

71) chain A
residue 69
type
sequence N
description BINDING SITE FOR RESIDUE EDO A 920
source : CC2

72) chain A
residue 70
type
sequence E
description BINDING SITE FOR RESIDUE EDO A 920
source : CC2

73) chain A
residue 699
type
sequence D
description BINDING SITE FOR RESIDUE EDO A 920
source : CC2

74) chain A
residue 702
type
sequence Q
description BINDING SITE FOR RESIDUE EDO A 920
source : CC2

75) chain A
residue 477
type
sequence N
description BINDING SITE FOR RESIDUE IPA A 921
source : CC3

76) chain A
residue 481
type
sequence Q
description BINDING SITE FOR RESIDUE IPA A 921
source : CC3

77) chain A
residue 667
type
sequence R
description BINDING SITE FOR RESIDUE IPA A 921
source : CC3

78) chain A
residue 692
type
sequence S
description BINDING SITE FOR RESIDUE IPA A 921
source : CC3

79) chain A
residue 151
type BINDING
sequence G
description BINDING => ECO:0000255
source Swiss-Prot : SWS_FT_FI1

80) chain A
residue 267
type MOD_RES
sequence S
description Phosphoserine => ECO:0000250|UniProtKB:Q9UM54
source Swiss-Prot : SWS_FT_FI2

81) chain A
residue 406
type MOD_RES
sequence V
description Phosphothreonine => ECO:0000269|PubMed:12682054
source Swiss-Prot : SWS_FT_FI3

82) chain A
residue 605
type MOD_RES
sequence L
description Phosphoserine => ECO:0000250|UniProtKB:Q64331
source Swiss-Prot : SWS_FT_FI4


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