eF-site ID 4d7e-ABCD PDB Code 4d7e Chain A, B, C, D click to enlarge Title An unprecedented NADPH domain conformation in Lysine Monooxygenase NbtG from Nocardia farcinica Classification OXIDOREDUCTASE Compound L-LYS MONOOXYGENASE Source Nocardia farcinica (strain IFM 10152) (Q5Z1T5_NOCFA) Sequence A:  METLLVVGAGPKALAVAAKSHVLRQLGLSAPRVIAVEAHA VGGNWLASGGWTDGRHRLGTSPEKDIGFPYHSTWARGHNR EINEAMMAFSWTSFLVEHGTYAEWIDRGRPSPQHHVWAKY LQWVARKIDLELVLGKVRTIRQGWSVEVAGATTELEADGL MITGPGQSTKALAAHPRVLSIAEFWDLAGKRKLPISSRAA VIGGGETAGSALDELVRHEMLTISVISPMASYFENSLFSD PTKWNALSIQERRDVIRRTDRGVFSVRVQESLLGDNRVHH LQGRVTRIVGQGDGVAVTLRNEMRADQVHNFDLVVDATGG QPLWFLDLFDSESADLLELAVGGPLTQQRIESSIGYDLAV TGLGAKLYLPNMAALAQGPGFPNLSCLGELSDRVLR B:  ETLLVVGAGPKALAVAAKSHVLRQLGLSAPRVIAVEAHAV GGNWLASGGWTDGRHRLGTSPEKDIGFPYHSTWARGHNRE INEAMMAFSWTSFLVEHGTYAEWIDRGRPSPQHHVWAKYL QWVARKIDLELVLGKVRTIRQRGWSVEVAGADGATTELEA DGLMITGPGQSTKALAAHPRVLSIAEFWDLAGKRKLPISS RAAVIGGGETAGSALDELVRHEMLTISVISPYFENSLFSD PTKWNALSIQERRDVIRRTDVFSVRVQESLLGDNRVHHLQ GRVTRIVGQGDGVAVTLDQVHNFDLVVDATGGQPLWFLDL FDSESADLLELAVGGPLTQQRIESSIGYDLAVTGLGAKLY LPNMAALAQGPGFPNLSCLGELSDRVLRAEPA C:  ETLLVVGAGPKALAVAAKSHVLRQLGLSAPRVIAVEAHAV GGNWLASGGWTDGRHRLGTSPEKDIGFPYHSTWARGHNRE INEAMMAFSWTSFLVEHGTYAEWIDRGRPSPQHHVWAKYL QWVARKIDLELVLGKVRTIRQGWSVEVAGAGATTELEADG LMITGPGQSTKALAAHPRVLSIAEFWDLAGKRKLPISSRA AVIGGGETAGSALDELVRHEMLTISVISPYFENSLFSDPT KWNALSIQERRDVQESLLGDNRVHHLQGRVTRIVGQGDGV AVTLRNDQVHNFDLVVDATGGQPLWFLDLFDSESADLLEL AVGGPLTQQRIESSIGYDLAVTGLGAKLYLPNMAALAQGP GFPNLSCLGELSDRVLR D:  ETLLVVGAGPKALAVAAKSHVLRQLGLSAPRVIAVEAHAV GGNWLASGGWTDGRHRLGTSPEKDIGFPYHSTWARGHNRE INEAMMAFSWTSFLVEHGTYAEWIDRGRPSPQHHVWAKYL QWVARKIDLELVLGKVRTIRQGWSVEVAGTTELEADGLMI TGPGQSTKALSIAEFWDLAVIGETAGSALDELVRHYFENS LFSDPTKWNALSIQERRDVIRRTDQPLWFLDLFDSESADL LELAVGGPLTQQRIESSIGYDLAVTGLGAKLYLPNMAALA QGPGFPNLSCLGELSDRVLR Description (1)  L-LYS MONOOXYGENASE Functional site 1) chain A residue 8 type sequence G description BINDING SITE FOR RESIDUE FAD A 500 source : AC1 2) chain A residue 10 type sequence G description BINDING SITE FOR RESIDUE FAD A 500 source : AC1 3) chain A residue 11 type sequence P description BINDING SITE FOR RESIDUE FAD A 500 source : AC1 4) chain A residue 12 type sequence K description BINDING SITE FOR RESIDUE FAD A 500 source : AC1 5) chain A residue 36 type sequence V description BINDING SITE FOR RESIDUE FAD A 500 source : AC1 6) chain A residue 37 type sequence E description BINDING SITE FOR RESIDUE FAD A 500 source : AC1 7) chain A residue 38 type sequence A description BINDING SITE FOR RESIDUE FAD A 500 source : AC1 8) chain A residue 39 type sequence H description BINDING SITE FOR RESIDUE FAD A 500 source : AC1 9) chain A residue 40 type sequence A description BINDING SITE FOR RESIDUE FAD A 500 source : AC1 10) chain A residue 43 type sequence G description BINDING SITE FOR RESIDUE FAD A 500 source : AC1 11) chain A residue 44 type sequence N description BINDING SITE FOR RESIDUE FAD A 500 source : AC1 12) chain A residue 45 type sequence W description BINDING SITE FOR RESIDUE FAD A 500 source : AC1 13) chain A residue 59 type sequence G description BINDING SITE FOR RESIDUE FAD A 500 source : AC1 14) chain A residue 60 type sequence T description BINDING SITE FOR RESIDUE FAD A 500 source : AC1 15) chain A residue 135 type sequence G description BINDING SITE FOR RESIDUE FAD A 500 source : AC1 16) chain A residue 136 type sequence K description BINDING SITE FOR RESIDUE FAD A 500 source : AC1 17) chain A residue 137 type sequence V description BINDING SITE FOR RESIDUE FAD A 500 source : AC1 18) chain A residue 173 type sequence T description BINDING SITE FOR RESIDUE FAD A 500 source : AC1 19) chain A residue 174 type sequence G description BINDING SITE FOR RESIDUE FAD A 500 source : AC1 20) chain A residue 175 type sequence P description BINDING SITE FOR RESIDUE FAD A 500 source : AC1 21) chain A residue 216 type sequence E description BINDING SITE FOR RESIDUE FAD A 500 source : AC1 22) chain A residue 217 type sequence T description BINDING SITE FOR RESIDUE FAD A 500 source : AC1 23) chain A residue 278 type sequence R description BINDING SITE FOR RESIDUE FAD A 500 source : AC1 24) chain A residue 399 type sequence P description BINDING SITE FOR RESIDUE FAD A 500 source : AC1 25) chain A residue 400 type sequence N description BINDING SITE FOR RESIDUE FAD A 500 source : AC1 26) chain A residue 401 type sequence L description BINDING SITE FOR RESIDUE FAD A 500 source : AC1 27) chain B residue 8 type sequence G description BINDING SITE FOR RESIDUE FAD B 500 source : AC2 28) chain B residue 10 type sequence G description BINDING SITE FOR RESIDUE FAD B 500 source : AC2 29) chain B residue 11 type sequence P description BINDING SITE FOR RESIDUE FAD B 500 source : AC2 30) chain B residue 12 type sequence K description BINDING SITE FOR RESIDUE FAD B 500 source : AC2 31) chain B residue 36 type sequence V description BINDING SITE FOR RESIDUE FAD B 500 source : AC2 32) chain B residue 37 type sequence E description BINDING SITE FOR RESIDUE FAD B 500 source : AC2 33) chain B residue 38 type sequence A description BINDING SITE FOR RESIDUE FAD B 500 source : AC2 34) chain B residue 39 type sequence H description BINDING SITE FOR RESIDUE FAD B 500 source : AC2 35) chain B residue 40 type sequence A description BINDING SITE FOR RESIDUE FAD B 500 source : AC2 36) chain B residue 43 type sequence G description BINDING SITE FOR RESIDUE FAD B 500 source : AC2 37) chain B residue 44 type sequence N description BINDING SITE FOR RESIDUE FAD B 500 source : AC2 38) chain B residue 45 type sequence W description BINDING SITE FOR RESIDUE FAD B 500 source : AC2 39) chain B residue 59 type sequence G description BINDING SITE FOR RESIDUE FAD B 500 source : AC2 40) chain B residue 60 type sequence T description BINDING SITE FOR RESIDUE FAD B 500 source : AC2 41) chain B residue 135 type sequence G description BINDING SITE FOR RESIDUE FAD B 500 source : AC2 42) chain B residue 136 type sequence K description BINDING SITE FOR RESIDUE FAD B 500 source : AC2 43) chain B residue 137 type sequence V description BINDING SITE FOR RESIDUE FAD B 500 source : AC2 44) chain B residue 173 type sequence T description BINDING SITE FOR RESIDUE FAD B 500 source : AC2 45) chain B residue 174 type sequence G description BINDING SITE FOR RESIDUE FAD B 500 source : AC2 46) chain B residue 175 type sequence P description BINDING SITE FOR RESIDUE FAD B 500 source : AC2 47) chain B residue 216 type sequence E description BINDING SITE FOR RESIDUE FAD B 500 source : AC2 48) chain B residue 217 type sequence T description BINDING SITE FOR RESIDUE FAD B 500 source : AC2 49) chain B residue 399 type sequence P description BINDING SITE FOR RESIDUE FAD B 500 source : AC2 50) chain B residue 400 type sequence N description BINDING SITE FOR RESIDUE FAD B 500 source : AC2 51) chain B residue 401 type sequence L description BINDING SITE FOR RESIDUE FAD B 500 source : AC2 52) chain C residue 8 type sequence G description BINDING SITE FOR RESIDUE FAD C 500 source : AC3 53) chain C residue 10 type sequence G description BINDING SITE FOR RESIDUE FAD C 500 source : AC3 54) chain C residue 11 type sequence P description BINDING SITE FOR RESIDUE FAD C 500 source : AC3 55) chain C residue 12 type sequence K description BINDING SITE FOR RESIDUE FAD C 500 source : AC3 56) chain C residue 36 type sequence V description BINDING SITE FOR RESIDUE FAD C 500 source : AC3 57) chain C residue 37 type sequence E description BINDING SITE FOR RESIDUE FAD C 500 source : AC3 58) chain C residue 38 type sequence A description BINDING SITE FOR RESIDUE FAD C 500 source : AC3 59) chain C residue 40 type sequence A description BINDING SITE FOR RESIDUE FAD C 500 source : AC3 60) chain C residue 43 type sequence G description BINDING SITE FOR RESIDUE FAD C 500 source : AC3 61) chain C residue 44 type sequence N description BINDING SITE FOR RESIDUE FAD C 500 source : AC3 62) chain C residue 45 type sequence W description BINDING SITE FOR RESIDUE FAD C 500 source : AC3 63) chain C residue 51 type sequence W description BINDING SITE FOR RESIDUE FAD C 500 source : AC3 64) chain C residue 58 type sequence L description BINDING SITE FOR RESIDUE FAD C 500 source : AC3 65) chain C residue 59 type sequence G description BINDING SITE FOR RESIDUE FAD C 500 source : AC3 66) chain C residue 60 type sequence T description BINDING SITE FOR RESIDUE FAD C 500 source : AC3 67) chain C residue 135 type sequence G description BINDING SITE FOR RESIDUE FAD C 500 source : AC3 68) chain C residue 136 type sequence K description BINDING SITE FOR RESIDUE FAD C 500 source : AC3 69) chain C residue 137 type sequence V description BINDING SITE FOR RESIDUE FAD C 500 source : AC3 70) chain C residue 173 type sequence T description BINDING SITE FOR RESIDUE FAD C 500 source : AC3 71) chain C residue 174 type sequence G description BINDING SITE FOR RESIDUE FAD C 500 source : AC3 72) chain C residue 175 type sequence P description BINDING SITE FOR RESIDUE FAD C 500 source : AC3 73) chain C residue 216 type sequence E description BINDING SITE FOR RESIDUE FAD C 500 source : AC3 74) chain C residue 217 type sequence T description BINDING SITE FOR RESIDUE FAD C 500 source : AC3 75) chain C residue 399 type sequence P description BINDING SITE FOR RESIDUE FAD C 500 source : AC3 76) chain C residue 400 type sequence N description BINDING SITE FOR RESIDUE FAD C 500 source : AC3 77) chain C residue 401 type sequence L description BINDING SITE FOR RESIDUE FAD C 500 source : AC3 78) chain D residue 8 type sequence G description BINDING SITE FOR RESIDUE FAD D 500 source : AC4 79) chain D residue 10 type sequence G description BINDING SITE FOR RESIDUE FAD D 500 source : AC4 80) chain D residue 11 type sequence P description BINDING SITE FOR RESIDUE FAD D 500 source : AC4 81) chain D residue 12 type sequence K description BINDING SITE FOR RESIDUE FAD D 500 source : AC4 82) chain D residue 36 type sequence V description BINDING SITE FOR RESIDUE FAD D 500 source : AC4 83) chain D residue 37 type sequence E description BINDING SITE FOR RESIDUE FAD D 500 source : AC4 84) chain D residue 38 type sequence A description BINDING SITE FOR RESIDUE FAD D 500 source : AC4 85) chain D residue 39 type sequence H description BINDING SITE FOR RESIDUE FAD D 500 source : AC4 86) chain D residue 43 type sequence G description BINDING SITE FOR RESIDUE FAD D 500 source : AC4 87) chain D residue 44 type sequence N description BINDING SITE FOR RESIDUE FAD D 500 source : AC4 88) chain D residue 45 type sequence W description BINDING SITE FOR RESIDUE FAD D 500 source : AC4 89) chain D residue 58 type sequence L description BINDING SITE FOR RESIDUE FAD D 500 source : AC4 90) chain D residue 59 type sequence G description BINDING SITE FOR RESIDUE FAD D 500 source : AC4 91) chain D residue 60 type sequence T description BINDING SITE FOR RESIDUE FAD D 500 source : AC4 92) chain D residue 137 type sequence V description BINDING SITE FOR RESIDUE FAD D 500 source : AC4 93) chain D residue 173 type sequence T description BINDING SITE FOR RESIDUE FAD D 500 source : AC4 94) chain D residue 174 type sequence G description BINDING SITE FOR RESIDUE FAD D 500 source : AC4 95) chain D residue 175 type sequence P description BINDING SITE FOR RESIDUE FAD D 500 source : AC4 96) chain D residue 177 type sequence Q description BINDING SITE FOR RESIDUE FAD D 500 source : AC4 97) chain D residue 217 type sequence T description BINDING SITE FOR RESIDUE FAD D 500 source : AC4 98) chain D residue 400 type sequence N description BINDING SITE FOR RESIDUE FAD D 500 source : AC4 99) chain D residue 401 type sequence L description BINDING SITE FOR RESIDUE FAD D 500 source : AC4

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