eF-site ID 4d30-B PDB Code 4d30 Chain B click to enlarge Title Structure of rat neuronal nitric oxide synthase heme domain in complex with N-2-(2-(1H-imidazol-1-yl)pyrimidin-4-yl)ethyl-3-(pyridin- 3-yl)propan-1-amine Classification OXIDOREDUCTASE Compound NITRIC OXIDE SYNTHASE, BRAIN Source Rattus norvegicus (Rat) (NOS1_RAT) Sequence B:  RFLKVKNWETDVVLTDTLHLKSTLETGCTEHICMGSIMLP VRTKDQLFPLAKEFLDQYYSSIKRFGSKAHMDRLEEVNKE IESTSTYQLKDTELIYGAKHAWRNASRCVGRIQWSKLQVF DARDCTTAHGMFNYICNHVKYATNKGNLRSAITIFPQRTD GKHDFRVWNSQLIRYAGYKQPDGSTLGDPANVQFTEICIQ QGWKAPRGRFDVLPLLLQANGNDPELFQIPPELVLEVPIR HPKFDWFKDLGLKWYGLPAVSNMLLEIGGLEFSACPFSGW YMGTEIGVRDYCDNSRYNILEEVAKKMDLDMRKTSSLWKD QALVEINIAVLYSFQSDKVTIVDHHSATESFIKHMENEYR CRGGCPADWVWIVPPMSGSITPVFHQEMLNYRLTPSFEYQ PDPWNTHVWKG Description (1)  NITRIC OXIDE SYNTHASE, BRAIN (E.C.1.14.13.39) Functional site 1) chain B residue 676 type sequence W description BINDING SITE FOR RESIDUE H4B A 760 source : AC2 2) chain B residue 691 type sequence F description BINDING SITE FOR RESIDUE H4B A 760 source : AC2 3) chain B residue 692 type sequence H description BINDING SITE FOR RESIDUE H4B A 760 source : AC2 4) chain B residue 693 type sequence Q description BINDING SITE FOR RESIDUE H4B A 760 source : AC2 5) chain B residue 694 type sequence E description BINDING SITE FOR RESIDUE H4B A 760 source : AC2 6) chain B residue 306 type sequence W description BINDING SITE FOR RESIDUE EG8 A 800 source : AC3 7) chain B residue 409 type sequence W description BINDING SITE FOR RESIDUE HEM B 750 source : AC5 8) chain B residue 412 type sequence A description BINDING SITE FOR RESIDUE HEM B 750 source : AC5 9) chain B residue 415 type sequence C description BINDING SITE FOR RESIDUE HEM B 750 source : AC5 10) chain B residue 457 type sequence S description BINDING SITE FOR RESIDUE HEM B 750 source : AC5 11) chain B residue 584 type sequence F description BINDING SITE FOR RESIDUE HEM B 750 source : AC5 12) chain B residue 585 type sequence S description BINDING SITE FOR RESIDUE HEM B 750 source : AC5 13) chain B residue 586 type sequence G description BINDING SITE FOR RESIDUE HEM B 750 source : AC5 14) chain B residue 587 type sequence W description BINDING SITE FOR RESIDUE HEM B 750 source : AC5 15) chain B residue 592 type sequence E description BINDING SITE FOR RESIDUE HEM B 750 source : AC5 16) chain B residue 678 type sequence W description BINDING SITE FOR RESIDUE HEM B 750 source : AC5 17) chain B residue 704 type sequence F description BINDING SITE FOR RESIDUE HEM B 750 source : AC5 18) chain B residue 706 type sequence Y description BINDING SITE FOR RESIDUE HEM B 750 source : AC5 19) chain B residue 334 type sequence S description BINDING SITE FOR RESIDUE H4B B 760 source : AC6 20) chain B residue 336 type sequence M description BINDING SITE FOR RESIDUE H4B B 760 source : AC6 21) chain B residue 596 type sequence R description BINDING SITE FOR RESIDUE H4B B 760 source : AC6 22) chain B residue 677 type sequence V description BINDING SITE FOR RESIDUE H4B B 760 source : AC6 23) chain B residue 678 type sequence W description BINDING SITE FOR RESIDUE H4B B 760 source : AC6 24) chain B residue 336 type sequence M description BINDING SITE FOR RESIDUE EG8 B 800 source : AC7 25) chain B residue 478 type sequence Q description BINDING SITE FOR RESIDUE EG8 B 800 source : AC7 26) chain B residue 565 type sequence P description BINDING SITE FOR RESIDUE EG8 B 800 source : AC7 27) chain B residue 566 type sequence A description BINDING SITE FOR RESIDUE EG8 B 800 source : AC7 28) chain B residue 567 type sequence V description BINDING SITE FOR RESIDUE EG8 B 800 source : AC7 29) chain B residue 419 type sequence I description BINDING SITE FOR RESIDUE ACT B 860 source : AC8 30) chain B residue 420 type sequence Q description BINDING SITE FOR RESIDUE ACT B 860 source : AC8 31) chain B residue 587 type sequence W description BINDING SITE FOR RESIDUE ACT B 860 source : AC8 32) chain B residue 649 type sequence V description BINDING SITE FOR RESIDUE ACT B 860 source : AC8 33) chain B residue 326 type sequence C description BINDING SITE FOR RESIDUE ZN A 1717 source : AC9 34) chain B residue 331 type sequence C description BINDING SITE FOR RESIDUE ZN A 1717 source : AC9 35) chain B residue 334 type BINDING sequence S description BINDING => ECO:0000250|UniProtKB:P29475 source Swiss-Prot : SWS_FT_FI1 36) chain B residue 478 type BINDING sequence Q description BINDING => ECO:0000250|UniProtKB:P29475 source Swiss-Prot : SWS_FT_FI1 37) chain B residue 587 type BINDING sequence W description BINDING => ECO:0000250|UniProtKB:P29475 source Swiss-Prot : SWS_FT_FI1 38) chain B residue 588 type BINDING sequence Y description BINDING => ECO:0000250|UniProtKB:P29475 source Swiss-Prot : SWS_FT_FI1 39) chain B residue 592 type BINDING sequence E description BINDING => ECO:0000250|UniProtKB:P29475 source Swiss-Prot : SWS_FT_FI1 40) chain B residue 677 type BINDING sequence V description BINDING => ECO:0000250|UniProtKB:P29475 source Swiss-Prot : SWS_FT_FI1 41) chain B residue 678 type BINDING sequence W description BINDING => ECO:0000250|UniProtKB:P29475 source Swiss-Prot : SWS_FT_FI1 42) chain B residue 691 type BINDING sequence F description BINDING => ECO:0000250|UniProtKB:P29475 source Swiss-Prot : SWS_FT_FI1 43) chain B residue 706 type BINDING sequence Y description BINDING => ECO:0000250|UniProtKB:P29475 source Swiss-Prot : SWS_FT_FI1 44) chain B residue 415 type BINDING sequence C description axial binding residue => ECO:0000250|UniProtKB:P29475 source Swiss-Prot : SWS_FT_FI2

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