eF-site ID 4csj-AB PDB Code 4csj Chain A, B click to enlarge Title The discovery of potent selective glucocorticoid receptor modulators, suitable for inhalation Classification SIGNALING PROTEIN Compound GLUCOCORTICOID RECEPTOR Source Homo sapiens (Human) (E7EWM1_HUMAN) Sequence A:  PTLVSLLEVIEPEVLYAGYDSSVPDSTWRIMTTLNMLGGR QMIAAVKWAKAIPGFRNLHLDDQMTLLQYSWMSLMAFALG WRSYRQSSANLLCFAPDLIINEQRMTLPDMYDQCKHMLYV SSELHRLQVSYEEYLCMKTLLLLSSVPKDGLKSQELFDEI RMTYIKELGKAIVKREGNSSQNWQRFYQLTKLLDSMHEVV ENLLNYCFQTFLDKTMSIEFPEMLAEIITNQIPKYSNGNI KKLLFHQ B:  ENALLRYLLDKDD Description Functional site 1) chain A residue 541 type sequence P description BINDING SITE FOR RESIDUE EDO A 1777 source : AC1 2) chain A residue 574 type sequence A description BINDING SITE FOR RESIDUE EDO A 1777 source : AC1 3) chain A residue 577 type sequence W description BINDING SITE FOR RESIDUE EDO A 1777 source : AC1 4) chain A residue 667 type sequence K description BINDING SITE FOR RESIDUE EDO A 1777 source : AC1 5) chain A residue 563 type sequence L description BINDING SITE FOR RESIDUE NN7 A 1778 source : AC2 6) chain A residue 564 type sequence N description BINDING SITE FOR RESIDUE NN7 A 1778 source : AC2 7) chain A residue 566 type sequence L description BINDING SITE FOR RESIDUE NN7 A 1778 source : AC2 8) chain A residue 567 type sequence G description BINDING SITE FOR RESIDUE NN7 A 1778 source : AC2 9) chain A residue 570 type sequence Q description BINDING SITE FOR RESIDUE NN7 A 1778 source : AC2 10) chain A residue 601 type sequence M description BINDING SITE FOR RESIDUE NN7 A 1778 source : AC2 11) chain A residue 604 type sequence M description BINDING SITE FOR RESIDUE NN7 A 1778 source : AC2 12) chain A residue 607 type sequence A description BINDING SITE FOR RESIDUE NN7 A 1778 source : AC2 13) chain A residue 608 type sequence L description BINDING SITE FOR RESIDUE NN7 A 1778 source : AC2 14) chain A residue 611 type sequence R description BINDING SITE FOR RESIDUE NN7 A 1778 source : AC2 15) chain A residue 623 type sequence F description BINDING SITE FOR RESIDUE NN7 A 1778 source : AC2 16) chain A residue 642 type sequence Q description BINDING SITE FOR RESIDUE NN7 A 1778 source : AC2 17) chain A residue 646 type sequence M description BINDING SITE FOR RESIDUE NN7 A 1778 source : AC2 18) chain A residue 736 type sequence C description BINDING SITE FOR RESIDUE NN7 A 1778 source : AC2 19) chain A residue 753 type sequence L description BINDING SITE FOR RESIDUE NN7 A 1778 source : AC2 20) chain A residue 703 type CROSSLNK sequence K description Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO) => ECO:0000269|PubMed:12144530 source Swiss-Prot : SWS_FT_FI1

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