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eF-site ID
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4cr3-Z |
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PDB Code
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4cr3 |
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Chain
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Z |
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click to enlarge
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Title
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Deep classification of a large cryo-EM dataset defines the conformational landscape of the 26S proteasome |
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Classification
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HYDROLASE |
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Compound
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PROTEASOME COMPONENT PRE3 |
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Source
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ORGANISM_COMMON: BAKER'S YEAST; ORGANISM_SCIENTIFIC: SACCHAROMYCES CEREVISIAE; |
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Sequence
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Z: |
LELLVERLKEDDSSLYEASLNALKESIKNSTSSMTAVPKP
LKFLRPTYPDLCSIYDKWTDPNLKSSLADVLSILAMTYSE
NGKHDSLRYRLLSDVSDFEGWGHEYIRHLALEIGEVYNDQ
VEKDAEDETSSDGSKSDGSAATSGFEFSKEDTLRLCLDIV
PYFLKHNGEEDAVDLLLEIESIDKLPQFVDENTFQRVCQY
MVACVPLLPPPEDVAFLKTAYSIYLSQNELTDAIALAVRL
GEEDMIRSVFDATSDPVMHKQLAYILAAQKTSFEYEGVQD
IIGNGKLSEHFLYLAKELNLTGPKVPEDIYKSHLDNSKSV
FSSAGLDSAQQNLASSFVNGFLNLGYCNDKLIVDNDNWVY
KTKGDGMTSAVASIGSIYQWNLDGLQQLDKYLYVDEPEVK
AGALLGIGISASGVHDGEVEPALLLLQDYVTNPDTKISSA
AILGLGIAFAGSKNDEVLGLLLPIAASTDLPIETAAMASL
ALAHVFVGTCNGDITTSIMDNFLERTAIELKTDWVRFLAL
ALGILYMGQGEQVDDVLETISAIEHPMTSAIEVLVGSCAY
TGTGDVLLIQDLLHRLTLAYAVLGIALIALGEDIGKEMSL
RHFGHLMHYGNEHIRRMVPLAMGIVSVSDPQMKVFDTLTR
FSHDADLEVSMNSIFAMGLCGAGTNNARLAQLLRQLASYY
SREQDALFITRLAQGLLHLGKGTMTMDVFNDAHVLNKVTL
ASILTTAVGLVSPSFMLKHHQLFYMLNAGIRPKFILALND
EGEPIKVNVRVGQPVLLNHGERAELETDEYISYTSHIEGV
VILKKNPDYREEE
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Description
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Functional site
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1)
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chain |
Z |
| residue |
187 |
| type |
MOD_RES |
| sequence |
S
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| description |
Phosphoserine => ECO:0007744|PubMed:18407956
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| source |
Swiss-Prot : SWS_FT_FI4
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2)
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chain |
Z |
| residue |
178 |
| type |
MOD_RES |
| sequence |
S
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| description |
Phosphoserine => ECO:0007744|PubMed:19779198
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| source |
Swiss-Prot : SWS_FT_FI1
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