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eF-site ID
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4cr2-P |
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PDB Code
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4cr2 |
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Chain
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P |
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click to enlarge
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Title
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Deep classification of a large cryo-EM dataset defines the conformational landscape of the 26S proteasome |
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Classification
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HYDROLASE |
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Compound
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PROTEASOME COMPONENT PRE3 |
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Source
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ORGANISM_COMMON: BAKER'S YEAST; ORGANISM_SCIENTIFIC: SACCHAROMYCES CEREVISIAE; |
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Sequence
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P: |
AQNDCNSALDQLLVLEKKTRQASDLASSKEVLAKIVDLLA
SRNKWDDLNEQLTLLSKKHGQLKLSIQYMIQKVMEYLKSS
KSLDLNTRISVIETIRVVTENKIFVEVERARVTKDLVEIK
KEEGKIDEAADILCELQVETYGSMEMSEKIQFILEQMELS
ILKGDYSQATVLSRKILKKTFKNPKYESLKLEYYNLLVKI
SLHKREYLEVAQYLQEIYQTDAIKSDEAKWKPVLSHIVYF
LVLSPYGNLQNDLIHKIQNDNNLKKLESQESLVKLFTTNE
LMRWPIVQKTYEPVLNEDDLAFGGEANKHHWEDLQKRVIE
HNLRVISEYYSRITLLRLNELLDLTESQTETYISDLVNQG
IIYAKVNRPAKIVNFEKPKNSSQLLNEWSHNVDELLEHIE
TIGHLITKEEIMHGL
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Description
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(1) |
PROTEASOME COMPONENT PRE3 (E.C.3.4.25.1), PROTEASOME COMPONENT PUP1 (E.C.3.4.25.1), PROTEASOME COMPONENT PUP3 (E.C.3.4.25.1), PROTEASOME COMPONENT C11 (E.C.3.4.25.1), PROTEASOME COMPONENT PRE2 (E.C.3.4.25.1), PROTEASOME COMPONENT C5 (E.C.3.4.25.1), PROTEASOME COMPONENT PRE4 (E.C.3.4.25.1), PROTEASOME COMPONENT C7-ALPHA (E.C.3.4.25.1), PROTEASOME COMPONENT Y7 (E.C.3.4.25.1), PROTEASOME COMPONENT Y13 (E.C.3.4.25.1), PROTEASOME COMPONENT PRE6 (E.C.3.4.25.1), PROTEASOME COMPONENT PUP2 (E.C.3.4.25.1), PROTEASOME COMPONENT PRE5 (E.C.3.4.25.1), 26S PROTEASE REGULATORY SUBUNIT 7 HOMOLOG, 26S PROTEASE REGULATORY SUBUNIT 4 HOMOLOG, 26S PROTEASE REGULATORY SUBUNIT 8 HOMOLOG, 26S PROTEASE REGULATORY SUBUNIT 6B HOMOLOG, 26S PROTEASE SUBUNIT RPT4, 26S PROTEASE REGULATORY SUBUNIT 6A, 26S PROTEASOME REGULATORY SUBUNIT RPN2, 26S PROTEASOME REGULATORY SUBUNIT RPN9, 26S PROTEASOME REGULATORY SUBUNIT RPN5, 26S PROTEASOME REGULATORY SUBUNIT RPN6, 26S PROTEASOME REGULATORY SUBUNIT RPN7, 26S PROTEASOME REGULATORY SUBUNIT RPN3, 26S PROTEASOME REGULATORY SUBUNIT RPN12, 26S PROTEASOME REGULATORY SUBUNIT RPN8, 26S PROTEASOME REGULATORY SUBUNIT RPN11, 26S PROTEASOME REGULATORY SUBUNIT RPN10, 26S PROTEASOME REGULATORY SUBUNIT RPN13, 26S PROTEASOME COMPLEX SUBUNIT SEM1
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