|
|
eF-site ID
|
4cdf-E |
|
PDB Code
|
4cdf |
|
Chain
|
E |
|
click to enlarge
|
|
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Title
|
Human DPP1 in complex with (2S,4S)-N-((1S)-1-cyano-2-(4-(4- cyanophenyl)phenyl)ethyl)-4-hydroxy-piperidine-2-carboxamide |
|
Classification
|
HYDROLASE |
|
Compound
|
DIPEPTIDYL PEPTIDASE 1 EXCLUSION DOMAIN CHAIN |
|
Source
|
(CATC_HUMAN) |
|
|
Sequence
|
E: |
LHLPTSWDWRNVHGINFVSPVRNQASCGSCYSFASMGMLE
ARIRILTNNSQTPILSPQEVVSCSQYAQGCEGGFPYLIAG
KYAQDFGLVEEACFPYTGTDSPCKMKEDCFRYYSSEYHYV
GGFYGGCNEALMKLELVHHGPMAVAFEVYDDFLHYKKGIY
HHT
|
|
|
Description
|
|
Functional site
|
|
|
1)
|
chain |
E |
| residue |
278 |
| type |
ACT_SITE |
| sequence |
F
|
| description |
ACT_SITE => ECO:0000255|PROSITE-ProRule:PRU10090
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
2)
|
chain |
E |
| residue |
280 |
| type |
ACT_SITE |
| sequence |
Y
|
| description |
ACT_SITE => ECO:0000255|PROSITE-ProRule:PRU10090
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
3)
|
chain |
E |
| residue |
323 |
| type |
ACT_SITE |
| sequence |
Y
|
| description |
ACT_SITE => ECO:0000255|PROSITE-ProRule:PRU10090
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
4)
|
chain |
E |
| residue |
252 |
| type |
CARBOHYD |
| sequence |
N
|
| description |
N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:19167329
|
| source |
Swiss-Prot : SWS_FT_FI3
|
|
|
|