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eF-site ID
|
4cde-B |
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PDB Code
|
4cde |
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Chain
|
B |
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click to enlarge
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Title
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Human DPP1 in complex with 4-amino-N-((1S)-1-cyano-2-(4-(4- cyanophenyl)phenyl)ethyl)tetrahydropyran-4-carboxamide |
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Classification
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HYDROLASE |
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Compound
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DIPEPTIDYL PEPTIDASE 1 EXCLUSION DOMAIN CHAIN |
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Source
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(CATC_HUMAN) |
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Sequence
|
B: |
HLPTSWDWRNVHGINFVSPVRNQASCGSCYSFASMGMLEA
RIRILTNNSQTPILSPQEVVSCSQYAQGCEGGFPYLIAGK
YAQDFGLVEEACFPYTGTDSPCKMKEDCFRYYSSEYHYVG
GFYGGCNEALMKLELVHHGPMAVAFEVYDDFLHYKKGIYH
H
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Description
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Functional site
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|
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1)
|
chain |
B |
| residue |
323 |
| type |
ACT_SITE |
| sequence |
Y
|
| description |
ACT_SITE => ECO:0000255|PROSITE-ProRule:PRU10090
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
2)
|
chain |
B |
| residue |
252 |
| type |
CARBOHYD |
| sequence |
N
|
| description |
N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:19167329
|
| source |
Swiss-Prot : SWS_FT_FI3
|
|
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3)
|
chain |
B |
| residue |
228-239 |
| type |
prosite |
| sequence |
QASCGSCYSFAS
|
| description |
THIOL_PROTEASE_CYS Eukaryotic thiol (cysteine) proteases cysteine active site. QAsCGSCYSfAS
|
| source |
prosite : PS00139
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