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eF-site ID
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4cde-B |
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PDB Code
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4cde |
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Chain
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B |
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click to enlarge
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Title
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Human DPP1 in complex with 4-amino-N-((1S)-1-cyano-2-(4-(4- cyanophenyl)phenyl)ethyl)tetrahydropyran-4-carboxamide |
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Classification
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HYDROLASE |
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Compound
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DIPEPTIDYL PEPTIDASE 1 EXCLUSION DOMAIN CHAIN |
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Source
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(CATC_HUMAN) |
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Sequence
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B: |
HLPTSWDWRNVHGINFVSPVRNQASCGSCYSFASMGMLEA
RIRILTNNSQTPILSPQEVVSCSQYAQGCEGGFPYLIAGK
YAQDFGLVEEACFPYTGTDSPCKMKEDCFRYYSSEYHYVG
GFYGGCNEALMKLELVHHGPMAVAFEVYDDFLHYKKGIYH
H
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Description
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(1) |
DIPEPTIDYL PEPTIDASE 1 EXCLUSION DOMAIN CHAIN (E.C.3.4.14.1), DIPEPTIDYL PEPTIDASE 1 HEAVY CHAIN (E.C.3.4.14.1), DIPEPTIDYL PEPTIDASE 1 LIGHT CHAIN (E.C.3.4.14.1)
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Functional site
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1)
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chain |
B |
| residue |
228-239 |
| type |
prosite |
| ligand |
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| sequence |
QASCGSCYSFAS
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| description |
Eukaryotic thiol (cysteine) proteases cysteine active site.Q-{V}-x-{DE}-[GE]-{F}-C-[YW]-{DN}-x-[STAGC]-[STAGCV].
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| source |
prosite : PS00139
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