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eF-site ID
|
4cde-C |
|
PDB Code
|
4cde |
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Chain
|
C |
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click to enlarge
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Title
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Human DPP1 in complex with 4-amino-N-((1S)-1-cyano-2-(4-(4- cyanophenyl)phenyl)ethyl)tetrahydropyran-4-carboxamide |
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Classification
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HYDROLASE |
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Compound
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DIPEPTIDYL PEPTIDASE 1 EXCLUSION DOMAIN CHAIN |
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Source
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(CATC_HUMAN) |
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Sequence
|
C: |
PFNPFELTNHAVLLVGYGTDSASGMDYWIVKNSWGTGWGE
NGYFRIRRGTDECAIESIAVAATPIPKL
|
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Description
|
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Functional site
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|
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1)
|
chain |
C |
| residue |
379-389 |
| type |
prosite |
| sequence |
TNHAVLLVGYG
|
| description |
THIOL_PROTEASE_HIS Eukaryotic thiol (cysteine) proteases histidine active site. TNHAVLLVGYG
|
| source |
prosite : PS00639
|
|
|
2)
|
chain |
C |
| residue |
398-417 |
| type |
prosite |
| sequence |
YWIVKNSWGTGWGENGYFRI
|
| description |
THIOL_PROTEASE_ASN Eukaryotic thiol (cysteine) proteases asparagine active site. YWIvKNSWgtgWGenGYFrI
|
| source |
prosite : PS00640
|
|
|
3)
|
chain |
C |
| residue |
381 |
| type |
ACT_SITE |
| sequence |
H
|
| description |
ACT_SITE => ECO:0000255|PROSITE-ProRule:PRU10089
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
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4)
|
chain |
C |
| residue |
403 |
| type |
ACT_SITE |
| sequence |
N
|
| description |
ACT_SITE => ECO:0000255|PROSITE-ProRule:PRU10090
|
| source |
Swiss-Prot : SWS_FT_FI2
|
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