eF-site ID 4cde-C
PDB Code 4cde
Chain C

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Title Human DPP1 in complex with 4-amino-N-((1S)-1-cyano-2-(4-(4- cyanophenyl)phenyl)ethyl)tetrahydropyran-4-carboxamide
Classification HYDROLASE
Compound DIPEPTIDYL PEPTIDASE 1 EXCLUSION DOMAIN CHAIN
Source (CATC_HUMAN)
Sequence C:  PFNPFELTNHAVLLVGYGTDSASGMDYWIVKNSWGTGWGE
NGYFRIRRGTDECAIESIAVAATPIPKL
Description


Functional site

1) chain C
residue 379-389
type prosite
sequence TNHAVLLVGYG
description THIOL_PROTEASE_HIS Eukaryotic thiol (cysteine) proteases histidine active site. TNHAVLLVGYG
source prosite : PS00639

2) chain C
residue 398-417
type prosite
sequence YWIVKNSWGTGWGENGYFRI
description THIOL_PROTEASE_ASN Eukaryotic thiol (cysteine) proteases asparagine active site. YWIvKNSWgtgWGenGYFrI
source prosite : PS00640

3) chain C
residue 381
type ACT_SITE
sequence H
description ACT_SITE => ECO:0000255|PROSITE-ProRule:PRU10089
source Swiss-Prot : SWS_FT_FI1

4) chain C
residue 403
type ACT_SITE
sequence N
description ACT_SITE => ECO:0000255|PROSITE-ProRule:PRU10090
source Swiss-Prot : SWS_FT_FI2


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