eF-site ID 4ccm-B PDB Code 4ccm Chain B click to enlarge Title 60S ribosomal protein L8 histidine hydroxylase (NO66) in complex with Mn(II), N-oxalylglycine (NOG) and 60S ribosomal protein L8 (RPL8 G220C) peptide fragment (complex-1) Classification OXIDOREDUCTASE Compound BIFUNCTIONAL LYSINE-SPECIFIC DEMETHYLASE AND HISTIDYL-HYDROXYLASE NO66 Source (RL8_HUMAN) Sequence B:  MSPLRRVLAELNRIPSSRRRAARLFEWLIAPMPPDHFYRR LWEREAVLVRRQDHTYYQGLFSTADLDSMLRNEEVQFGQH LDAARYINGRRETLNPPGRALPAAAWSLYQAGCSLRLLCP QAFSTTVWQFLAVLQEQFGSMAGSNVYLTPPNSQGFAPHY DDIEAFVLQLEGRKLWRVYRPRVPTEELALTSSPNFSQDD LGEPVLQTVLEPGDLLYFPRGFIHQAECQDGVHSLHLTLS TYQRNTWGDFLEAILPLAVQAAMEENVEFRRGLPRDFMDY MGAQHSDSKDPRRTAFMEKVRVLVARLGHFAPVDAVADQR AKDFIHDSLPPVLTDRERALSVYGLPIRWEAGEPVNVGAQ LTTETEVHMLQDGIARLVGEGGHLFLYYTVENSRVYHLEE PKCLEIYPQQADAMELLLGSYPEFVRVGDLPCDSVEDQLS LATTLYDKGLLLTKMPLAL Description Functional site 1) chain B residue 224 type sequence E description BINDING SITE FOR RESIDUE EDO A 903 source : AC3 2) chain B residue 340 type sequence H description BINDING SITE FOR RESIDUE MN B 901 source : AC4 3) chain B residue 342 type sequence D description BINDING SITE FOR RESIDUE MN B 901 source : AC4 4) chain B residue 405 type sequence H description BINDING SITE FOR RESIDUE MN B 901 source : AC4 5) chain B residue 328 type sequence Y description BINDING SITE FOR RESIDUE OGA B 902 source : AC5 6) chain B residue 337 type sequence F description BINDING SITE FOR RESIDUE OGA B 902 source : AC5 7) chain B residue 340 type sequence H description BINDING SITE FOR RESIDUE OGA B 902 source : AC5 8) chain B residue 342 type sequence D description BINDING SITE FOR RESIDUE OGA B 902 source : AC5 9) chain B residue 355 type sequence K description BINDING SITE FOR RESIDUE OGA B 902 source : AC5 10) chain B residue 405 type sequence H description BINDING SITE FOR RESIDUE OGA B 902 source : AC5 11) chain B residue 417 type sequence H description BINDING SITE FOR RESIDUE OGA B 902 source : AC5 12) chain B residue 419 type sequence T description BINDING SITE FOR RESIDUE OGA B 902 source : AC5 13) chain B residue 458 type sequence F description BINDING SITE FOR RESIDUE EDO B 903 source : AC6 14) chain B residue 320 type sequence G description BINDING SITE FOR RESIDUE EDO B 904 source : AC7 15) chain B residue 321 type sequence S description BINDING SITE FOR RESIDUE EDO B 904 source : AC7 16) chain B residue 426 type sequence N description BINDING SITE FOR RESIDUE EDO B 904 source : AC7 17) chain B residue 501 type sequence R description BINDING SITE FOR RESIDUE EDO B 904 source : AC7 18) chain B residue 340 type MOD_RES sequence H description (3S)-3-hydroxyhistidine => ECO:0000269|PubMed:23103944 source Swiss-Prot : SWS_FT_FI1 19) chain B residue 342 type MOD_RES sequence D description (3S)-3-hydroxyhistidine => ECO:0000269|PubMed:23103944 source Swiss-Prot : SWS_FT_FI1 20) chain B residue 405 type MOD_RES sequence H description (3S)-3-hydroxyhistidine => ECO:0000269|PubMed:23103944 source Swiss-Prot : SWS_FT_FI1

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