eF-site ID 4c9z-B PDB Code 4c9z Chain B click to enlarge Title Crystal structure of Siah1 at 1.95 A resolution Classification LIGASE Compound E3 UBIQUITIN-PROTEIN LIGASE SIAH1 Source Homo sapiens (Human) (SIAH1_HUMAN) Sequence B:  LFPCKYASSGCEITLPHTEKADHEELCEFRPYSCPCPGAS CKWQGSLDAVMPHLMHQHKSITTLQGEDIVFLATDINLPG AVDWVMMQSCFGFHFMLVLEKQEKYDGHQQFFAIVQLIGT RKQAENFAYRLELNGHRRRLTWEATPRSIHEGIATAIMNS DCLVFDTSIAQLFAENGNLGINVTISMC Description Functional site 1) chain B residue 128 type sequence C description BINDING SITE FOR RESIDUE ZN B 283 source : AC3 2) chain B residue 135 type sequence C description BINDING SITE FOR RESIDUE ZN B 283 source : AC3 3) chain B residue 147 type sequence H description BINDING SITE FOR RESIDUE ZN B 283 source : AC3 4) chain B residue 152 type sequence H description BINDING SITE FOR RESIDUE ZN B 283 source : AC3 5) chain B residue 98 type sequence C description BINDING SITE FOR RESIDUE ZN B 284 source : AC4 6) chain B residue 105 type sequence C description BINDING SITE FOR RESIDUE ZN B 284 source : AC4 7) chain B residue 117 type sequence H description BINDING SITE FOR RESIDUE ZN B 284 source : AC4 8) chain B residue 121 type sequence C description BINDING SITE FOR RESIDUE ZN B 284 source : AC4 9) chain B residue 224 type sequence R description BINDING SITE FOR RESIDUE CL B 1286 source : AC6 10) chain B residue 231 type sequence R description BINDING SITE FOR RESIDUE TRS B 1283 source : AC8 11) chain B residue 232 type sequence R description BINDING SITE FOR RESIDUE TRS B 1283 source : AC8 12) chain B residue 233 type sequence R description BINDING SITE FOR RESIDUE TRS B 1283 source : AC8 13) chain B residue 222 type sequence A description BINDING SITE FOR RESIDUE GOL A 1286 source : AC9 14) chain B residue 231 type sequence R description BINDING SITE FOR RESIDUE SO4 B 1284 source : BC2 15) chain B residue 232 type sequence R description BINDING SITE FOR RESIDUE SO4 B 1284 source : BC2 16) chain B residue 146 type sequence P description BINDING SITE FOR RESIDUE SO4 B 1285 source : BC3 17) chain B residue 147 type sequence H description BINDING SITE FOR RESIDUE SO4 B 1285 source : BC3 18) chain B residue 150 type sequence H description BINDING SITE FOR RESIDUE SO4 B 1285 source : BC3 19) chain B residue 151 type sequence Q description BINDING SITE FOR RESIDUE SO4 B 1285 source : BC3 20) chain B residue 98 type BINDING sequence C description BINDING => ECO:0000269|PubMed:28546513, ECO:0007744|PDB:5WZZ source Swiss-Prot : SWS_FT_FI2 21) chain B residue 105 type BINDING sequence C description BINDING => ECO:0000269|PubMed:28546513, ECO:0007744|PDB:5WZZ source Swiss-Prot : SWS_FT_FI2 22) chain B residue 117 type BINDING sequence H description BINDING => ECO:0000269|PubMed:28546513, ECO:0007744|PDB:5WZZ source Swiss-Prot : SWS_FT_FI2 23) chain B residue 121 type BINDING sequence C description BINDING => ECO:0000269|PubMed:28546513, ECO:0007744|PDB:5WZZ source Swiss-Prot : SWS_FT_FI2 24) chain B residue 128 type BINDING sequence C description BINDING => ECO:0000269|PubMed:16085652, ECO:0000269|PubMed:28546513, ECO:0007744|PDB:2A25, ECO:0007744|PDB:5WZZ source Swiss-Prot : SWS_FT_FI3 25) chain B residue 135 type BINDING sequence C description BINDING => ECO:0000269|PubMed:16085652, ECO:0000269|PubMed:28546513, ECO:0007744|PDB:2A25, ECO:0007744|PDB:5WZZ source Swiss-Prot : SWS_FT_FI3 26) chain B residue 147 type BINDING sequence H description BINDING => ECO:0000269|PubMed:16085652, ECO:0000269|PubMed:28546513, ECO:0007744|PDB:2A25, ECO:0007744|PDB:5WZZ source Swiss-Prot : SWS_FT_FI3 27) chain B residue 152 type BINDING sequence H description BINDING => ECO:0000269|PubMed:16085652, ECO:0000269|PubMed:28546513, ECO:0007744|PDB:2A25, ECO:0007744|PDB:5WZZ source Swiss-Prot : SWS_FT_FI3

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