eF-site ID 4c75-ABCD PDB Code 4c75 Chain A, B, C, D click to enlarge Title Consensus (ALL-CON) beta-lactamase class A Classification HYDROLASE Compound BETA-LACTAMASE Source (4C75) Sequence A:  AAALNDEFAALEKQYGGRLGVYALDTGTGRTIAYRADERF PMCSTFKALAAAAVLAQVDAGKESLDRRITYTKDDLVDYS PVTEKHVGTGMTLAELCEAAITYSDNTAANLLLDEIGGPK GLTAFLRSIGDDVTRLDRWEPELNEALPGDPRDTTTPAAM AATLRALLLGDALSPASRAQLTDWMRGNTTGDKLIRAGLP AGWRVGDKTGTGSYGTRNDIAIIWPPNRAPIVLAIYSTGS TADAKERNALIAEAAKIVAEAL B:  AAALNDEFAALEKQYGGRLGVYALDTGTGRTIAYRADERF PMCSTFKALAAAAVLAQVDAGKESLDRRITYTKDDLVDYS PVTEKHVGTGMTLAELCEAAITYSDNTAANLLLDEIGGPK GLTAFLRSIGDDVTRLDRWEPELNEALPGDPRDTTTPAAM AATLRALLLGDALSPASRAQLTDWMRGNTTGDKLIRAGLP AGWRVGDKTGTGSYGTRNDIAIIWPPNRAPIVLAIYSTGS TADAKERNALIAEAAKIVAEAL C:  AAALNDEFAALEKQYGGRLGVYALDTGTGRTIAYRADERF PMCSTFKALAAAAVLAQVDAGKESLDRRITYTKDDLVDYS PVTEKHVGTGMTLAELCEAAITYSDNTAANLLLDEIGGPK GLTAFLRSIGDDVTRLDRWEPELNEALPGDPRDTTTPAAM AATLRALLLGDALSPASRAQLTDWMRGNTTGDKLIRAGLP AGWRVGDKTGTGSYGTRNDIAIIWPPNRAPIVLAIYSTGS TADAKERNALIAEAAKIVAEAL D:  AAALNDEFAALEKQYGGRLGVYALDTGTGRTIAYRADERF PMCSTFKALAAAAVLAQVDAGKESLDRRITYTKDDLVDYS PVTEKHVGTGMTLAELCEAAITYSDNTAANLLLDEIGGPK GLTAFLRSIGDDVTRLDRWEPELNEALPGDPRDTTTPAAM AATLRALLLGDALSPASRAQLTDWMRGNTTGDKLIRAGLP AGWRVGDKTGTGSYGTRNDIAIIWPPNRAPIVLAIYSTGS TADAKERNALIAEAAKIVAEAL Description Functional site 1) chain A residue 70 type sequence S description BINDING SITE FOR RESIDUE SO4 A 291 source : AC1 2) chain A residue 130 type sequence S description BINDING SITE FOR RESIDUE SO4 A 291 source : AC1 3) chain A residue 234 type sequence K description BINDING SITE FOR RESIDUE SO4 A 291 source : AC1 4) chain A residue 235 type sequence T description BINDING SITE FOR RESIDUE SO4 A 291 source : AC1 5) chain A residue 236 type sequence G description BINDING SITE FOR RESIDUE SO4 A 291 source : AC1 6) chain A residue 237 type sequence T description BINDING SITE FOR RESIDUE SO4 A 291 source : AC1 7) chain A residue 244 type sequence R description BINDING SITE FOR RESIDUE SO4 A 291 source : AC1 8) chain A residue 108 type sequence V description BINDING SITE FOR RESIDUE ACT A 292 source : AC2 9) chain A residue 111 type sequence K description BINDING SITE FOR RESIDUE ACT A 292 source : AC2 10) chain A residue 129 type sequence Y description BINDING SITE FOR RESIDUE ACT A 292 source : AC2 11) chain A residue 150 type sequence A description BINDING SITE FOR RESIDUE PEG A 293 source : AC3 12) chain A residue 153 type sequence R description BINDING SITE FOR RESIDUE PEG A 293 source : AC3 13) chain A residue 154 type sequence S description BINDING SITE FOR RESIDUE PEG A 293 source : AC3 14) chain A residue 70 type sequence S description BINDING SITE FOR RESIDUE NA A 294 source : AC4 15) chain A residue 236 type sequence G description BINDING SITE FOR RESIDUE NA A 294 source : AC4 16) chain A residue 237 type sequence T description BINDING SITE FOR RESIDUE NA A 294 source : AC4 17) chain A residue 285 type sequence I description BINDING SITE FOR RESIDUE PEG A 295 source : AC5 18) chain A residue 288 type sequence E description BINDING SITE FOR RESIDUE PEG A 295 source : AC5 19) chain B residue 70 type sequence S description BINDING SITE FOR RESIDUE SO4 B 291 source : AC6 20) chain B residue 130 type sequence S description BINDING SITE FOR RESIDUE SO4 B 291 source : AC6 21) chain B residue 234 type sequence K description BINDING SITE FOR RESIDUE SO4 B 291 source : AC6 22) chain B residue 235 type sequence T description BINDING SITE FOR RESIDUE SO4 B 291 source : AC6 23) chain B residue 236 type sequence G description BINDING SITE FOR RESIDUE SO4 B 291 source : AC6 24) chain B residue 237 type sequence T description BINDING SITE FOR RESIDUE SO4 B 291 source : AC6 25) chain B residue 244 type sequence R description BINDING SITE FOR RESIDUE SO4 B 291 source : AC6 26) chain B residue 107 type sequence P description BINDING SITE FOR RESIDUE PEG B 292 source : AC7 27) chain B residue 108 type sequence V description BINDING SITE FOR RESIDUE PEG B 292 source : AC7 28) chain B residue 111 type sequence K description BINDING SITE FOR RESIDUE PEG B 292 source : AC7 29) chain B residue 129 type sequence Y description BINDING SITE FOR RESIDUE PEG B 292 source : AC7 30) chain B residue 164 type sequence R description BINDING SITE FOR RESIDUE ACT B 293 source : AC8 31) chain B residue 178 type sequence R description BINDING SITE FOR RESIDUE ACT B 293 source : AC8 32) chain C residue 165 type sequence W description BINDING SITE FOR RESIDUE ACT B 293 source : AC8 33) chain A residue 173 type sequence L description BINDING SITE FOR RESIDUE ACT B 294 source : AC9 34) chain A residue 174 type sequence P description BINDING SITE FOR RESIDUE ACT B 294 source : AC9 35) chain A residue 241 type sequence Y description BINDING SITE FOR RESIDUE ACT B 294 source : AC9 36) chain B residue 51 type sequence T description BINDING SITE FOR RESIDUE ACT B 294 source : AC9 37) chain B residue 191 type sequence R description BINDING SITE FOR RESIDUE ACT B 294 source : AC9 38) chain B residue 195 type sequence L description BINDING SITE FOR RESIDUE ACT B 294 source : AC9 39) chain A residue 43 type sequence R description BINDING SITE FOR RESIDUE PEG B 295 source : BC1 40) chain A residue 61 type sequence R description BINDING SITE FOR RESIDUE PEG B 295 source : BC1 41) chain A residue 64 type sequence E description BINDING SITE FOR RESIDUE PEG B 295 source : BC1 42) chain B residue 201 type sequence P description BINDING SITE FOR RESIDUE PEG B 295 source : BC1 43) chain B residue 202 type sequence A description BINDING SITE FOR RESIDUE PEG B 295 source : BC1 44) chain B residue 205 type sequence A description BINDING SITE FOR RESIDUE PEG B 295 source : BC1 45) chain C residue 70 type sequence S description BINDING SITE FOR RESIDUE SO4 C 291 source : BC2 46) chain C residue 130 type sequence S description BINDING SITE FOR RESIDUE SO4 C 291 source : BC2 47) chain C residue 235 type sequence T description BINDING SITE FOR RESIDUE SO4 C 291 source : BC2 48) chain C residue 236 type sequence G description BINDING SITE FOR RESIDUE SO4 C 291 source : BC2 49) chain C residue 237 type sequence T description BINDING SITE FOR RESIDUE SO4 C 291 source : BC2 50) chain C residue 244 type sequence R description BINDING SITE FOR RESIDUE SO4 C 291 source : BC2 51) chain C residue 30 type sequence N description BINDING SITE FOR RESIDUE ACT C 292 source : BC3 52) chain C residue 61 type sequence R description BINDING SITE FOR RESIDUE ACT C 292 source : BC3 53) chain D residue 70 type sequence S description BINDING SITE FOR RESIDUE SO4 D 291 source : BC4 54) chain D residue 130 type sequence S description BINDING SITE FOR RESIDUE SO4 D 291 source : BC4 55) chain D residue 235 type sequence T description BINDING SITE FOR RESIDUE SO4 D 291 source : BC4 56) chain D residue 236 type sequence G description BINDING SITE FOR RESIDUE SO4 D 291 source : BC4 57) chain D residue 237 type sequence T description BINDING SITE FOR RESIDUE SO4 D 291 source : BC4 58) chain D residue 244 type sequence R description BINDING SITE FOR RESIDUE SO4 D 291 source : BC4 59) chain D residue 281 type sequence E description BINDING SITE FOR RESIDUE ACT D 292 source : BC5 60) chain D residue 284 type sequence K description BINDING SITE FOR RESIDUE ACT D 292 source : BC5 61) chain D residue 288 type sequence E description BINDING SITE FOR RESIDUE ACT D 292 source : BC5 62) chain A residue 153 type sequence R description BINDING SITE FOR RESIDUE ACT D 293 source : BC6 63) chain A residue 156 type sequence G description BINDING SITE FOR RESIDUE ACT D 293 source : BC6 64) chain D residue 63 type sequence D description BINDING SITE FOR RESIDUE ACT D 293 source : BC6 65) chain D residue 215 type sequence T description BINDING SITE FOR RESIDUE ACT D 294 source : BC7 66) chain D residue 216 type sequence T description BINDING SITE FOR RESIDUE ACT D 294 source : BC7 67) chain D residue 217 type sequence G description BINDING SITE FOR RESIDUE ACT D 294 source : BC7 68) chain D residue 218 type sequence D description BINDING SITE FOR RESIDUE ACT D 294 source : BC7 69) chain A residue 66-81 type prosite sequence FPMCSTFKALAAAAVL description BETA_LACTAMASE_A Beta-lactamase class-A active site. FpMCSTfKalaAAAVL source prosite : PS00146

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