eF-site ID 4c3h-B PDB Code 4c3h Chain B click to enlarge Title Structure of 14-subunit RNA polymerase I at 3.27 A resolution, crystal form C2-93 Classification TRANSCRIPTION Compound DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA190 Source ORGANISM_COMMON: BAKER'S YEAST; ORGANISM_SCIENTIFIC: SACCHAROMYCES CEREVISIAE; Sequence B:  RTADFRTLERESRFINPPKDKSAFPLLQEAVQPHIGSFNA LTEGPDGGLLNLGVKDIGEKVIFDGKPLNSEEISNSGYLG NKLSVSVEQVSIAKPMSNDSAVERKVYPSESRQRLTSYRG KLLLKLKWSVNNGEENLFEVRDCGGLPVMLQSNRCHLNKM SPYELVQHKEESDEIGGYFIVNGIEKLIRMLIVQRRNHPM AIIRPSFANRGASYSHYGIQIRSVRPDQTSQTNVLHYLND GQVTFRFSWRKNEYLVPVVMILKALCHTSDREIFDGIIGN DVKDSFLTDRLELLLRGFKKRYPHLQNRTQVLQYLGDKFR VVFQASPDQSDLEVGQEVLDRIVLVHLGKDGSQDKFRMLL FMIRKLYSLVAGECSPDNPDATQHQEVLLGGFLYGMILKE KIDEYLQNIIAQVRMDINRGMAINFKDKRYMSRVLMRVNE NIGSKMQYFLSTGNLVSQSGLDLQQVSGYTVVAEKINFYR FISHFRMVHRGSFFAQLKTTTVRKLLPESWGFLCPVHTPD GSPCGLLNHFAHKCRISTQQSDVSRIPSILYSLGVAPASH TFAAGPSLCCVQIDGKIIGWVSHEQGKIIADTLRYWKVEG KTPGLPIDLEIGYVPPSTRGQYPGLYLFGGHSRMLRPVRY LPLDKEDIVGPFEQVYMNIAVTPQEIQNNVHTHVEFTPTN ILSILANLTPFSDFNQSPRNMYQCQMGKQTMGTPGVALCH RSDNKLYRLQTGQTPIVKANLYDDYGMDNFPNGFNAVVAV ISYTGYDMDDAMIINKSADERGFGYGTMYKTEKVDLALDP ITQHFGFGNDEWPKEWLEKLDEDGLPYIGTYVEEGDPICA YFDDTLNKTKIKTYHSSEPAYIEEVNLIGDESNKFQELQT VSIKYRIRRTPQIGDKFSSRHGQKGVCSRKWPTIDMPFSE TGIQPDIIINPHAFPSRMTIGMFVESLAGKAGALHGIAQD STPWIFNEDDTPADYFGEQLAKAGYNYHGNEPMYSGATGE ELRADIYVGVVYYQRLRHMVNDKFQVRSTGPVNSLTMQPV KGRKRHGGIRVGEMERDALIGHGTSFLLQDRLLNSSDYTQ ASVCRECGSILTTQQSVPRIGSISTVCCRRCSMRFEDAKK GEKIFIDDSQIWEDGQGNKFVGGNETTTVAIPFVLKYLDS ELSAMGIRLRYNVEPK Description (1)  DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA190 (E.C.2.7.7.6), DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA135 (E.C.2.7.7.6), DNA-DIRECTED RNA POLYMERASES I AND III SUBUNIT RPAC1, DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA14, DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 1, DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 2, DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA43, DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 3, DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA12, DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 5, DNA-DIRECTED RNA POLYMERASES I AND III SUBUNIT RPAC2, DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 4, DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA49, DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA34 Functional site 1) chain B residue 1104 type sequence C description BINDING SITE FOR RESIDUE ZN B 2204 source : AC3 2) chain B residue 1107 type sequence C description BINDING SITE FOR RESIDUE ZN B 2204 source : AC3 3) chain B residue 1128 type sequence C description BINDING SITE FOR RESIDUE ZN B 2204 source : AC3 4) chain B residue 1131 type sequence C description BINDING SITE FOR RESIDUE ZN B 2204 source : AC3 5) chain B residue 1156 type MOD_RES sequence S description Phosphoserine => ECO:0007744|PubMed:19779198 source Swiss-Prot : SWS_FT_FI4 6) chain B residue 914-926 type prosite sequence GDKFSSRHGQKGV description RNA_POL_BETA RNA polymerases beta chain signature. GdKFSSrHGQKGV source prosite : PS01166

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