eF-site ID 4byf-C PDB Code 4byf Chain C click to enlarge Title Crystal structure of human Myosin 1c in complex with calmodulin in the pre-power stroke state Classification HYDROLASE Compound UNCONVENTIONAL MYOSIN-IC Source Homo sapiens (Human) (CALM_HUMAN) Sequence C:  RVGVQDFVLLENFTSEAAFIENLRRRFRENLIYTYIGPVL VSVNPYRDLQIYSRQHMERYRGVSFYEVPPHLFAVADTVY RALRTERRDQAVMISGESGAGKTEATKRLLQFYAETCPAP ERGGAVRDRLLQSNPVLEAFGNAKTLRNDNSSRFGKYMDV QFDFKGAPVGGHILSYLLEKSRVVHQNHGERNFHIFYQLL EGGEEETLRRLGLERNPQSYLYLVKGQCAKVSSINDKSDW KVVRKALTVIDFTEDEVEDLLSIVASVLHLGNIHFAANEN AQVTTENQLKYLTRLLSVEGSTLREALTHRKIELLSPLNL EQAAYARDALAKAVYSRTFTWLVGKINRSLASKDVESPSW RSTTVLGLLDIYGFEVFQHNSFEQFCINYCNEKLQQLFIE LTLKSEQEEYEAEGIAWEPVQYFNNKIICDLVEEKFKGII SILDEECLRPGEATDLTFLEKLEDTVKHHPHFLTHKLADR KSLGRGEFRLLHYAGEVTYSVTGFLDKNNDLLFRNLKETM CSSKNPIMSQCFDRSKRPETVATQFKMSLLQLVEILQSKE PAYVRCIKPNDAKQPGRFDEVLIRHQVKYLGLLENLRVRR AGFAYRRKYEAFLQRYKSLCPETWPTWAGRPQDGVAVLVR HLGYKPEEYKMGRTKIFIRFPKTLFATEDALEVRRQSLAT KIQAAWRGFHWRQKFL Description Functional site 1) chain C residue 112 type sequence T description BINDING SITE FOR RESIDUE MG C 1000 source : AC3 2) chain C residue 161 type sequence S description BINDING SITE FOR RESIDUE MG C 1000 source : AC3 3) chain C residue 53 type sequence N description BINDING SITE FOR RESIDUE AOV C 1001 source : AC4 4) chain C residue 56 type sequence R description BINDING SITE FOR RESIDUE AOV C 1001 source : AC4 5) chain C residue 61 type sequence Y description BINDING SITE FOR RESIDUE AOV C 1001 source : AC4 6) chain C residue 106 type sequence E description BINDING SITE FOR RESIDUE AOV C 1001 source : AC4 7) chain C residue 107 type sequence S description BINDING SITE FOR RESIDUE AOV C 1001 source : AC4 8) chain C residue 108 type sequence G description BINDING SITE FOR RESIDUE AOV C 1001 source : AC4 9) chain C residue 109 type sequence A description BINDING SITE FOR RESIDUE AOV C 1001 source : AC4 10) chain C residue 110 type sequence G description BINDING SITE FOR RESIDUE AOV C 1001 source : AC4 11) chain C residue 111 type sequence K description BINDING SITE FOR RESIDUE AOV C 1001 source : AC4 12) chain C residue 112 type sequence T description BINDING SITE FOR RESIDUE AOV C 1001 source : AC4 13) chain C residue 113 type sequence E description BINDING SITE FOR RESIDUE AOV C 1001 source : AC4 14) chain C residue 157 type sequence N description BINDING SITE FOR RESIDUE AOV C 1001 source : AC4 15) chain C residue 159 type sequence N description BINDING SITE FOR RESIDUE AOV C 1001 source : AC4 16) chain C residue 160 type sequence S description BINDING SITE FOR RESIDUE AOV C 1001 source : AC4 17) chain C residue 161 type sequence S description BINDING SITE FOR RESIDUE AOV C 1001 source : AC4 18) chain C residue 388 type sequence Y description BINDING SITE FOR RESIDUE AOV C 1001 source : AC4 19) chain C residue 389 type sequence G description BINDING SITE FOR RESIDUE AOV C 1001 source : AC4

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