eF-site ID 4bvw-A PDB Code 4bvw Chain A click to enlarge Title Identification of small molecule inhibitors selective for apo(a) kringles KIV-7, KIV-10 and KV. Classification HYDROLASE Compound APOLIPOPROTEIN(A) Source Homo sapiens (Human) (APOA_HUMAN) Sequence A:  DCYHGDGQSYRGSFSTTVTGRTCQSWSSMTPHWHQRTTEY YPNGGLTRNYCRNPDAEIRPWCYTMDPSVRWEYCALTQC Description Functional site 1) chain A residue 3 type sequence H description BINDING SITE FOR RESIDUE CL A 1079 source : AC1 2) chain A residue 8 type sequence S description BINDING SITE FOR RESIDUE CL A 1079 source : AC1 3) chain A residue 9 type sequence Y description BINDING SITE FOR RESIDUE CL A 1079 source : AC1 4) chain A residue 35 type sequence R description BINDING SITE FOR RESIDUE CL A 1081 source : AC3 5) chain A residue 20 type sequence R description BINDING SITE FOR RESIDUE EDO B 1081 source : AC5 6) chain A residue 54 type sequence D description BINDING SITE FOR RESIDUE HKY A 1080 source : AC6 7) chain A residue 56 type sequence E description BINDING SITE FOR RESIDUE HKY A 1080 source : AC6 8) chain A residue 60 type sequence W description BINDING SITE FOR RESIDUE HKY A 1080 source : AC6 9) chain A residue 62 type sequence Y description BINDING SITE FOR RESIDUE HKY A 1080 source : AC6 10) chain A residue 69 type sequence R description BINDING SITE FOR RESIDUE HKY A 1080 source : AC6 11) chain A residue 70 type sequence W description BINDING SITE FOR RESIDUE HKY A 1080 source : AC6 12) chain A residue 49-61 type prosite sequence YCRNPDAEIRPWC description KRINGLE_1 Kringle domain signature. YCRNpdaeirp.WC source prosite : PS00021

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