eF-site ID 4bvw-B PDB Code 4bvw Chain B click to enlarge Title Identification of small molecule inhibitors selective for apo(a) kringles KIV-7, KIV-10 and KV. Classification HYDROLASE Compound APOLIPOPROTEIN(A) Source Homo sapiens (Human) (APOA_HUMAN) Sequence B:  DCYHGDGQSYRGSFSTTVTGRTCQSWSSMTPHWHQRTTEY YPNGGLTRNYCRNPDAEIRPWCYTMDPSVRWEYCALTQC Description Functional site 1) chain B residue 40 type sequence Y description BINDING SITE FOR RESIDUE CL B 1079 source : AC2 2) chain B residue 41 type sequence P description BINDING SITE FOR RESIDUE CL B 1079 source : AC2 3) chain B residue 42 type sequence N description BINDING SITE FOR RESIDUE CL B 1079 source : AC2 4) chain B residue 43 type sequence G description BINDING SITE FOR RESIDUE CL B 1079 source : AC2 5) chain B residue 2 type sequence Y description BINDING SITE FOR RESIDUE CL B 1080 source : AC4 6) chain B residue 77 type sequence Q description BINDING SITE FOR RESIDUE CL B 1080 source : AC4 7) chain B residue 2 type sequence Y description BINDING SITE FOR RESIDUE EDO B 1081 source : AC5 8) chain B residue 57 type sequence I description BINDING SITE FOR RESIDUE EDO B 1081 source : AC5 9) chain B residue 77 type sequence Q description BINDING SITE FOR RESIDUE EDO B 1081 source : AC5 10) chain B residue 54 type sequence D description BINDING SITE FOR RESIDUE HKY B 1082 source : AC7 11) chain B residue 56 type sequence E description BINDING SITE FOR RESIDUE HKY B 1082 source : AC7 12) chain B residue 60 type sequence W description BINDING SITE FOR RESIDUE HKY B 1082 source : AC7 13) chain B residue 62 type sequence Y description BINDING SITE FOR RESIDUE HKY B 1082 source : AC7 14) chain B residue 69 type sequence R description BINDING SITE FOR RESIDUE HKY B 1082 source : AC7 15) chain B residue 70 type sequence W description BINDING SITE FOR RESIDUE HKY B 1082 source : AC7

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