eF-site ID 4bvv-A PDB Code 4bvv Chain A click to enlarge Title Identification of small molecule inhibitors selective for apo(a) kringles KIV-7, KIV-10 and KV. Classification HYDROLASE Compound APOLIPOPROTEIN(A) Source Homo sapiens (Human) (APOA_HUMAN) Sequence A:  DCMFGNGKGYRGKKATTVTGTPCQEWAAQEPHRHSTFIPG TNKWAGLEKNYCRNPDGDINGPWCYTMNPRKLFDYCDIPL C Description Functional site 1) chain A residue 3 type sequence F description BINDING SITE FOR RESIDUE CPF A 1081 source : AC1 2) chain A residue 34 type sequence S description BINDING SITE FOR RESIDUE CPF A 1081 source : AC1 3) chain A residue 35 type sequence T description BINDING SITE FOR RESIDUE CPF A 1081 source : AC1 4) chain A residue 55 type sequence D description BINDING SITE FOR RESIDUE CPF A 1081 source : AC1 5) chain A residue 57 type sequence D description BINDING SITE FOR RESIDUE CPF A 1081 source : AC1 6) chain A residue 58 type sequence I description BINDING SITE FOR RESIDUE CPF A 1081 source : AC1 7) chain A residue 59 type sequence N description BINDING SITE FOR RESIDUE CPF A 1081 source : AC1 8) chain A residue 62 type sequence W description BINDING SITE FOR RESIDUE CPF A 1081 source : AC1 9) chain A residue 64 type sequence Y description BINDING SITE FOR RESIDUE CPF A 1081 source : AC1 10) chain A residue 71 type sequence L description BINDING SITE FOR RESIDUE CPF A 1081 source : AC1 11) chain A residue 72 type sequence F description BINDING SITE FOR RESIDUE CPF A 1081 source : AC1 12) chain A residue 0 type sequence D description BINDING SITE FOR RESIDUE SO4 A 1082 source : AC2 13) chain A residue 9 type sequence Y description BINDING SITE FOR RESIDUE SO4 A 1082 source : AC2 14) chain A residue 12 type sequence K description BINDING SITE FOR RESIDUE SO4 A 1082 source : AC2 15) chain A residue 13 type sequence K description BINDING SITE FOR RESIDUE SO4 A 1082 source : AC2 16) chain A residue 50-63 type prosite sequence YCRNPDGDINGPWC description KRINGLE_1 Kringle domain signature. YCRNpdgdingpWC source prosite : PS00021

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