eF-site ID 4bv7-A PDB Code 4bv7 Chain A click to enlarge Title Identification of small molecule inhibitors selective for apo(a) kringles KIV-7, KIV-10 and KV. Classification HYDROLASE Compound APOLIPOPROTEIN(A) Source Homo sapiens (Human) (APOA_HUMAN) Sequence A:  QCYHGNGQSYRGTFSTTVTGRTCQSWSSMTPHRHQRTPEN YPNDGLTMNYCRNPDADTGPWCFTMDPSIRWEYCALTRC Description Functional site 1) chain A residue 20 type sequence R description BINDING SITE FOR RESIDUE ACT A 1081 source : AC1 2) chain A residue 48 type sequence M description BINDING SITE FOR RESIDUE ACT A 1081 source : AC1 3) chain A residue 50 type sequence Y description BINDING SITE FOR RESIDUE ACT A 1081 source : AC1 4) chain A residue 31 type sequence H description BINDING SITE FOR RESIDUE ACT A 1082 source : AC2 5) chain A residue 32 type sequence R description BINDING SITE FOR RESIDUE ACT A 1082 source : AC2 6) chain A residue 71 type sequence R description BINDING SITE FOR RESIDUE ACT A 1082 source : AC2 7) chain A residue 55 type sequence D description BINDING SITE FOR RESIDUE BV7 A 1083 source : AC3 8) chain A residue 57 type sequence D description BINDING SITE FOR RESIDUE BV7 A 1083 source : AC3 9) chain A residue 62 type sequence W description BINDING SITE FOR RESIDUE BV7 A 1083 source : AC3 10) chain A residue 64 type sequence F description BINDING SITE FOR RESIDUE BV7 A 1083 source : AC3 11) chain A residue 68 type sequence P description BINDING SITE FOR RESIDUE BV7 A 1083 source : AC3 12) chain A residue 71 type sequence R description BINDING SITE FOR RESIDUE BV7 A 1083 source : AC3 13) chain A residue 72 type sequence W description BINDING SITE FOR RESIDUE BV7 A 1083 source : AC3 14) chain A residue 50-63 type prosite sequence YCRNPDADTGPWC description KRINGLE_1 Kringle domain signature. YCRNpdadtgp.WC source prosite : PS00021

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