eF-site ID 4bux-C PDB Code 4bux Chain C click to enlarge Title Crystal structure of human tankyrase 2 in complex with 3-((4-(4-oxo-3, 4-dihydroquinazolin-2-yl)phenyl)methyl)imidazolidine-2,4-dione Classification TRANSFERASE Compound TANKYRASE-2 Source (TNKS2_HUMAN) Sequence C:  GTILIDLSPDDKEFQSVEEEMQSTVREHRDGGHAGGIFNR YNILKIQKVCNKKLWERYTHRRKEVSEENHNHANERMLFH GSPFVNAIIHKGFDERHAYIGGMFGAGIYFAENSSKSNQY VYGIGGGTGCPVHKDRSCYICHRQLLFCRVTLGKSFLQFS AMKMAHSPPGHHSVTGRPSVNGLALAEYVIYRGEQAYPEY LITYQIMRPE Description Functional site 1) chain C residue 1081 type sequence C description BINDING SITE FOR RESIDUE ZN C 2162 source : AC2 2) chain C residue 1084 type sequence H description BINDING SITE FOR RESIDUE ZN C 2162 source : AC2 3) chain C residue 1089 type sequence C description BINDING SITE FOR RESIDUE ZN C 2162 source : AC2 4) chain C residue 1092 type sequence C description BINDING SITE FOR RESIDUE ZN C 2162 source : AC2 5) chain C residue 977 type sequence R description BINDING SITE FOR RESIDUE SO4 C 2163 source : AC4 6) chain C residue 979 type sequence H description BINDING SITE FOR RESIDUE SO4 C 2163 source : AC4 7) chain C residue 980 type sequence R description BINDING SITE FOR RESIDUE SO4 C 2163 source : AC4 8) chain C residue 1067 type sequence K description BINDING SITE FOR RESIDUE SO4 C 2163 source : AC4 9) chain C residue 1070 type sequence Q description BINDING SITE FOR RESIDUE SO4 C 2163 source : AC4 10) chain C residue 990 type sequence N description BINDING SITE FOR RESIDUE SO4 C 2164 source : AC6 11) chain C residue 991 type sequence R description BINDING SITE FOR RESIDUE SO4 C 2164 source : AC6 12) chain C residue 1160 type sequence P description BINDING SITE FOR RESIDUE SO4 C 2164 source : AC6 13) chain C residue 1161 type sequence E description BINDING SITE FOR RESIDUE SO4 C 2164 source : AC6 14) chain C residue 1031 type sequence H description BINDING SITE FOR RESIDUE F35 C 2165 source : AC9 15) chain C residue 1032 type sequence G description BINDING SITE FOR RESIDUE F35 C 2165 source : AC9 16) chain C residue 1034 type sequence P description BINDING SITE FOR RESIDUE F35 C 2165 source : AC9 17) chain C residue 1035 type sequence F description BINDING SITE FOR RESIDUE F35 C 2165 source : AC9 18) chain C residue 1049 type sequence A description BINDING SITE FOR RESIDUE F35 C 2165 source : AC9 19) chain C residue 1050 type sequence Y description BINDING SITE FOR RESIDUE F35 C 2165 source : AC9 20) chain C residue 1060 type sequence Y description BINDING SITE FOR RESIDUE F35 C 2165 source : AC9 21) chain C residue 1067 type sequence K description BINDING SITE FOR RESIDUE F35 C 2165 source : AC9 22) chain C residue 1068 type sequence S description BINDING SITE FOR RESIDUE F35 C 2165 source : AC9 23) chain C residue 1071 type sequence Y description BINDING SITE FOR RESIDUE F35 C 2165 source : AC9 24) chain C residue 1075 type sequence I description BINDING SITE FOR RESIDUE F35 C 2165 source : AC9 25) chain C residue 1138 type sequence E description BINDING SITE FOR RESIDUE F35 C 2165 source : AC9 26) chain C residue 1081 type BINDING sequence C description BINDING => ECO:0000250|UniProtKB:O95271 source Swiss-Prot : SWS_FT_FI1 27) chain C residue 1084 type BINDING sequence H description BINDING => ECO:0000250|UniProtKB:O95271 source Swiss-Prot : SWS_FT_FI1 28) chain C residue 1089 type BINDING sequence C description BINDING => ECO:0000250|UniProtKB:O95271 source Swiss-Prot : SWS_FT_FI1 29) chain C residue 1092 type BINDING sequence C description BINDING => ECO:0000250|UniProtKB:O95271 source Swiss-Prot : SWS_FT_FI1

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