eF-site ID 4bqg-A PDB Code 4bqg Chain A click to enlarge Title structure of HSP90 with an inhibitor bound Classification CHAPERONE Compound HSP90AA1 PROTEIN Source Homo sapiens (Human) (Q2VPJ6_HUMAN) Sequence A:  EVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDA LDKIRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTG IGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFG VGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTD TGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIG YPITLFVEK Description (1)  HSP90AA1 PROTEIN Functional site 1) chain A residue 51 type sequence N description BINDING SITE FOR RESIDUE 50Q A 1225 source : AC1 2) chain A residue 55 type sequence A description BINDING SITE FOR RESIDUE 50Q A 1225 source : AC1 3) chain A residue 93 type sequence D description BINDING SITE FOR RESIDUE 50Q A 1225 source : AC1 4) chain A residue 98 type sequence M description BINDING SITE FOR RESIDUE 50Q A 1225 source : AC1 5) chain A residue 138 type sequence F description BINDING SITE FOR RESIDUE 50Q A 1225 source : AC1 6) chain A residue 162 type sequence W description BINDING SITE FOR RESIDUE 50Q A 1225 source : AC1 7) chain A residue 184 type sequence T description BINDING SITE FOR RESIDUE 50Q A 1225 source : AC1 8) chain A residue 186 type sequence V description BINDING SITE FOR RESIDUE 50Q A 1225 source : AC1 9) chain A residue 51 type BINDING sequence N description source Swiss-Prot : SWS_FT_FI1 10) chain A residue 93 type BINDING sequence D description source Swiss-Prot : SWS_FT_FI1 11) chain A residue 138 type BINDING sequence F description source Swiss-Prot : SWS_FT_FI1 12) chain A residue 38-47 type prosite sequence YSNKEIFLRE description HSP90 Heat shock hsp90 proteins family signature. YsNKEIFLRE source prosite : PS00298 13) chain A residue 112 type BINDING sequence K description BINDING => ECO:0000250 source Swiss-Prot : SWS_FT_FI2 14) chain A residue 58 type MOD_RES sequence K description N6-acetyllysine => ECO:0000250|UniProtKB:P07901 source Swiss-Prot : SWS_FT_FI3 15) chain A residue 84 type MOD_RES sequence K description N6-acetyllysine => ECO:0000250|UniProtKB:P07901 source Swiss-Prot : SWS_FT_FI3

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