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eF-site ID
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4bk5-A |
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PDB Code
|
4bk5 |
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Chain
|
A |
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click to enlarge
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Title
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crystal structure of the human EphA4 ectodomain in complex with human ephrin A5 (amine-methylated sample) |
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Classification
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SIGNALING PROTEIN |
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Compound
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EPHRIN TYPE-A RECEPTOR 4 |
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Source
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(EFNA5_HUMAN) |
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Sequence
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A: |
PANEVTLLDSRSVQGELGWIASPLEGGWEEVSIMDEKNTP
IRTYQVCNVMEPSQNNWLRTDWITREGAQRVYIEIKFTLR
DCNSLPGVMGTCKETFNLYYYESDNDKERFIRENQFVKID
TIAADESFTQVDIGDRIMKLNTEIRDVGPLSKKGFYLAFQ
DVGACIALVSVRVFYKKCPLTVRNLAQFPDTITGADTSSL
VEVRGSCVNNSEEKDVPKMYCGADGEWLVPIGNCLCNAGH
EERSGECQACKIGYYKALSTDATCAKCPPHSYSVWEGATS
CTCDRGFFRADNDAASMPCTRPPSAPLNLISNVNETSVNL
EWSSPQNTGGRQDISYNVVCKKCGAGDPSKCRPCGSGVHY
TPQQNGLKTTKVSITDLLAHTNYTFEIWAVNGVSKYNPNP
DQSVSVTVTTNQAAPSSIALVQAKEVTRYSVALAWLEPDR
PNGVILEYEVKYYEKDQNERSYRIVRTAARNTDIKGLNPL
TSYVFHVRARTAAGYGDFSEPLEVTTN
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Description
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Functional site
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1)
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chain |
A |
| residue |
185-205 |
| type |
prosite |
| sequence |
FQDVGACIALVSVRVFYKKCP
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| description |
RECEPTOR_TYR_KIN_V_1 Receptor tyrosine kinase class V signature 1. FqDvGACIALVSVRVfykKCP
|
| source |
prosite : PS00790
|
|
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2)
|
chain |
A |
| residue |
247-267 |
| type |
prosite |
| sequence |
CGADGEWLVPIGNCLCNAGHE
|
| description |
RECEPTOR_TYR_KIN_V_2 Receptor tyrosine kinase class V signature 2. CgaDGEWlv.PIGnClCnaGHE
|
| source |
prosite : PS00791
|
|
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3)
|
chain |
A |
| residue |
235 |
| type |
CARBOHYD |
| sequence |
N
|
| description |
N-linked (GlcNAc...) asparagine => ECO:0000255
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
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4)
|
chain |
A |
| residue |
340 |
| type |
CARBOHYD |
| sequence |
N
|
| description |
N-linked (GlcNAc...) asparagine => ECO:0000255
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
5)
|
chain |
A |
| residue |
408 |
| type |
CARBOHYD |
| sequence |
N
|
| description |
N-linked (GlcNAc...) asparagine => ECO:0000255
|
| source |
Swiss-Prot : SWS_FT_FI2
|
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|
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