eF-site ID 4b8u-ABCDE PDB Code 4b8u Chain A, B, C, D, E click to enlarge Title Crystal Structure of 3-hydroxydecanoyl-Acyl Carrier Protein Dehydratase (FabA) from Pseudomonas aeruginosa in complex with N- isobutyl-2-(5-(2-thienyl)-1,2-oxazol-3-yl-)methoxy)acetamide Classification LYASE Compound 3-HYDROXYDECANOYL-[ACYL-CARRIER-PROTEIN] DEHYDRATASE Source Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228) (FABA_PSEAE) Sequence A:  TKQHAFTREDLLRCSRGELFGPGNAQLPAPNMLMIDRIVH ISDVGGKYGKGELVAELDINPDLWFFACHFEGDPVMPGCL GLDAMWQLVGFYLGWQGNPGRGRALGSGEVKFFGQVLPTA KKVTYNIHIKRTINRSLVLAIADGTVSVDGREIYSAEGLR VGLFTSTDSF B:  KQHAFTREDLLRCSRGELFGPGNAQLPAPNMLMIDRIVHI SDVGGKYGKGELVAELDINPDLWFFACHFEGDPVMPGCLG LDAMWQLVGFYLGWQGNPGRGRALGSGEVKFFGQVLPTAK KVTYNIHIKRTINLVLAIADGTVSVDGREIYSAEGLRVGL FTSTDSF C:  TKQHAFTREDLLRCSRGELFGPGNAQLPAPNMLMIDRIVH ISDVGGKYGKGELVAELDINPDLWFFACHFEGDPVMPGCL GLDAMWQLVGFYLGWQGNPGRGRALGSGEVKFFGQVLPTA KKVTYNIHIKRTINLVLAIADGTVSVDGREIYSAEGLRVG LFT D:  KQHAFTREDLLRCSRGELFGPGNAQLPAPNMLMIDRIVHI SDVGGKYGKGELVAELDINPDLWFFACHFEGDPVMPGCLG LDAMWQLVGFYLGWQGNPGRGRALGSGEVKFFGQVLPTAK KVTYNIHIKRTINLVLAIADGTVSVDGREIYSAEGLRVGL FTSTD E:  KQHAFTREDLLRCSRGELFGPGNAQLPAPNMLMIDRIVHI SDVGGKYGKGELVAELDINPDLWFFACHFEGDPVMPGCLG LDAMWQLVGFYLGWQGNPGRGRALGSGEVKFFGQVLPTAK KVTYNIHIKRTINRSLVLAIADGTVSVDGREIYSAEGLRV GLFTSTDSF Description Functional site 1) chain A residue 105 type sequence A description BINDING SITE FOR RESIDUE IBK B 501 source : AC1 2) chain A residue 106 type sequence L description BINDING SITE FOR RESIDUE IBK B 501 source : AC1 3) chain A residue 171 type sequence F description BINDING SITE FOR RESIDUE IBK B 501 source : AC1 4) chain B residue 79 type sequence G description BINDING SITE FOR RESIDUE IBK B 501 source : AC1 5) chain B residue 112 type sequence K description BINDING SITE FOR RESIDUE IBK B 501 source : AC1 6) chain B residue 113 type sequence F description BINDING SITE FOR RESIDUE IBK B 501 source : AC1 7) chain B residue 115 type sequence G description BINDING SITE FOR RESIDUE IBK B 501 source : AC1 8) chain B residue 116 type sequence Q description BINDING SITE FOR RESIDUE IBK B 501 source : AC1 9) chain E residue 48 type sequence K description BINDING SITE FOR RESIDUE IBK B 501 source : AC1 10) chain E residue 49 type sequence Y description BINDING SITE FOR RESIDUE IBK B 501 source : AC1 11) chain E residue 50 type sequence G description BINDING SITE FOR RESIDUE IBK B 501 source : AC1 12) chain C residue 72 type sequence E description BINDING SITE FOR RESIDUE SO4 C 1167 source : AC2 13) chain C residue 73 type sequence G description BINDING SITE FOR RESIDUE SO4 C 1167 source : AC2 14) chain D residue 23 type sequence P description BINDING SITE FOR RESIDUE SO4 C 1167 source : AC2 15) chain D residue 24 type sequence G description BINDING SITE FOR RESIDUE SO4 C 1167 source : AC2 16) chain D residue 27 type sequence Q description BINDING SITE FOR RESIDUE SO4 C 1167 source : AC2 17) chain E residue 6 type sequence A description BINDING SITE FOR RESIDUE SO4 C 1167 source : AC2 18) chain E residue 8 type sequence T description BINDING SITE FOR RESIDUE SO4 C 1167 source : AC2 19) chain E residue 11 type sequence D description BINDING SITE FOR RESIDUE SO4 C 1167 source : AC2 20) chain A residue 70 type ACT_SITE sequence H description ACT_SITE => ECO:0000250 source Swiss-Prot : SWS_FT_FI1 21) chain B residue 70 type ACT_SITE sequence H description ACT_SITE => ECO:0000250 source Swiss-Prot : SWS_FT_FI1 22) chain C residue 70 type ACT_SITE sequence H description ACT_SITE => ECO:0000250 source Swiss-Prot : SWS_FT_FI1 23) chain D residue 70 type ACT_SITE sequence H description ACT_SITE => ECO:0000250 source Swiss-Prot : SWS_FT_FI1 24) chain E residue 70 type ACT_SITE sequence H description ACT_SITE => ECO:0000250 source Swiss-Prot : SWS_FT_FI1

Display surface Download Links