eF-site ID 4b79-AB PDB Code 4b79 Chain A, B click to enlarge Title THE AEROPATH PROJECT AND PSEUDOMONAS AERUGINOSA HIGH-THROUGHPUT CRYSTALLOGRAPHIC STUDIES FOR ASSESSMENT OF POTENTIAL TARGETS IN EARLY STAGE DRUG DISCOVERY. Classification OXIDOREDUCTASE Compound PROBABLE SHORT-CHAIN DEHYDROGENASE Source Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228) (Q9HWT0_PSEAE) Sequence A:  MVFQHDIYAGQQVLVTGGSSGIGAAIAMQFAELGAEVVAL GLDADGVHAPRHPRIRREELDITDSQRLQRLFEALPRLDV LVNNAGISRDREEYDLATFERVLRLNLSAAMLASQLARPL LAQRGGSILNIASMYSTFGSADRPAYSASKGAIVQLTRSL ACEYAAERIRVNAIAPGWIDTPKADVEATRRIMQRTPLAR WGEAPEVASAAAFLCGPGASFVTGAVLAVDGGYLCA B:  MVFQHDIYAGQQVLVTGGSSGIGAAIAMQFAELGAEVVAL GLDADGVHAPRHPRIRREELDITDSQRLQRLFEALPRLDV LVNNAGISRDREEYDLATFERVLRLNLSAAMLASQLARPL LAQRGGSILNIASMYSTFGSADRPAYSASKGAIVQLTRSL ACEYAAERIRVNAIAPGWIDTDVEATRRIMQRTPLARWGE APEVASAAAFLCGPGASFVTGAVLAVDGGYLCA Description Functional site 1) chain B residue 17 type sequence G description BINDING SITE FOR RESIDUE NAD B 1242 source : AC1 2) chain B residue 19 type sequence S description BINDING SITE FOR RESIDUE NAD B 1242 source : AC1 3) chain B residue 20 type sequence S description BINDING SITE FOR RESIDUE NAD B 1242 source : AC1 4) chain B residue 21 type sequence G description BINDING SITE FOR RESIDUE NAD B 1242 source : AC1 5) chain B residue 22 type sequence I description BINDING SITE FOR RESIDUE NAD B 1242 source : AC1 6) chain B residue 41 type sequence G description BINDING SITE FOR RESIDUE NAD B 1242 source : AC1 7) chain B residue 42 type sequence L description BINDING SITE FOR RESIDUE NAD B 1242 source : AC1 8) chain B residue 60 type sequence L description BINDING SITE FOR RESIDUE NAD B 1242 source : AC1 9) chain B residue 61 type sequence D description BINDING SITE FOR RESIDUE NAD B 1242 source : AC1 10) chain B residue 62 type sequence I description BINDING SITE FOR RESIDUE NAD B 1242 source : AC1 11) chain B residue 84 type sequence N description BINDING SITE FOR RESIDUE NAD B 1242 source : AC1 12) chain B residue 85 type sequence A description BINDING SITE FOR RESIDUE NAD B 1242 source : AC1 13) chain B residue 86 type sequence G description BINDING SITE FOR RESIDUE NAD B 1242 source : AC1 14) chain B residue 105 type sequence L description BINDING SITE FOR RESIDUE NAD B 1242 source : AC1 15) chain B residue 131 type sequence I description BINDING SITE FOR RESIDUE NAD B 1242 source : AC1 16) chain B residue 132 type sequence A description BINDING SITE FOR RESIDUE NAD B 1242 source : AC1 17) chain B residue 146 type sequence Y description BINDING SITE FOR RESIDUE NAD B 1242 source : AC1 18) chain B residue 150 type sequence K description BINDING SITE FOR RESIDUE NAD B 1242 source : AC1 19) chain B residue 176 type sequence P description BINDING SITE FOR RESIDUE NAD B 1242 source : AC1 20) chain B residue 177 type sequence G description BINDING SITE FOR RESIDUE NAD B 1242 source : AC1 21) chain B residue 179 type sequence I description BINDING SITE FOR RESIDUE NAD B 1242 source : AC1 22) chain B residue 181 type sequence T description BINDING SITE FOR RESIDUE NAD B 1242 source : AC1 23) chain A residue 17 type sequence G description BINDING SITE FOR RESIDUE NAD A 1242 source : AC2 24) chain A residue 19 type sequence S description BINDING SITE FOR RESIDUE NAD A 1242 source : AC2 25) chain A residue 20 type sequence S description BINDING SITE FOR RESIDUE NAD A 1242 source : AC2 26) chain A residue 21 type sequence G description BINDING SITE FOR RESIDUE NAD A 1242 source : AC2 27) chain A residue 22 type sequence I description BINDING SITE FOR RESIDUE NAD A 1242 source : AC2 28) chain A residue 41 type sequence G description BINDING SITE FOR RESIDUE NAD A 1242 source : AC2 29) chain A residue 42 type sequence L description BINDING SITE FOR RESIDUE NAD A 1242 source : AC2 30) chain A residue 60 type sequence L description BINDING SITE FOR RESIDUE NAD A 1242 source : AC2 31) chain A residue 61 type sequence D description BINDING SITE FOR RESIDUE NAD A 1242 source : AC2 32) chain A residue 62 type sequence I description BINDING SITE FOR RESIDUE NAD A 1242 source : AC2 33) chain A residue 84 type sequence N description BINDING SITE FOR RESIDUE NAD A 1242 source : AC2 34) chain A residue 86 type sequence G description BINDING SITE FOR RESIDUE NAD A 1242 source : AC2 35) chain A residue 87 type sequence I description BINDING SITE FOR RESIDUE NAD A 1242 source : AC2 36) chain A residue 105 type sequence L description BINDING SITE FOR RESIDUE NAD A 1242 source : AC2 37) chain A residue 131 type sequence I description BINDING SITE FOR RESIDUE NAD A 1242 source : AC2 38) chain A residue 132 type sequence A description BINDING SITE FOR RESIDUE NAD A 1242 source : AC2 39) chain A residue 146 type sequence Y description BINDING SITE FOR RESIDUE NAD A 1242 source : AC2 40) chain A residue 150 type sequence K description BINDING SITE FOR RESIDUE NAD A 1242 source : AC2 41) chain A residue 176 type sequence P description BINDING SITE FOR RESIDUE NAD A 1242 source : AC2 42) chain A residue 177 type sequence G description BINDING SITE FOR RESIDUE NAD A 1242 source : AC2 43) chain A residue 179 type sequence I description BINDING SITE FOR RESIDUE NAD A 1242 source : AC2 44) chain A residue 181 type sequence T description BINDING SITE FOR RESIDUE NAD A 1242 source : AC2 45) chain A residue 133-161 type prosite sequence SMYSTFGSADRPAYSASKGAIVQLTRSLA description ADH_SHORT Short-chain dehydrogenases/reductases family signature. SmystfgsadRpaYSASKGAIvQLTrSLA source prosite : PS00061

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