eF-site ID 4b3s-BCDEFGHIJKLMNOPQRSTV PDB Code 4b3s Chain B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T, V click to enlarge Title Crystal structure of the 30S ribosome in complex with compound 37 Classification RIBOSOME Compound 16S RIBOSOMAL RNA Source ORGANISM_SCIENTIFIC: THERMUS THERMOPHILUS HB8; Sequence B:  VKELLEAGVHFGHERKRWNPKFARYIYAERNGIHIIDLQK TMEELERTFRFIEDLAMRGGTILFVGTKKQAQDIVRMEAE RAGMPYVNQRWLGGMLTNFKTISQRVHRLEELEALFASPE IEERPKKEQVRLKHELERLQKYLSGFRLLKRLPDAIFVVD PTKEAIAVREARKLFIPVIALADTDSDPDLVDYIIPGNDD AIRSIQLILSRAVDLIIQARGGVVEPSPSYALVQE C:  GNKIHPIGFRLGITRDWESRWYAGKKQYRHLLLEDQRIRG LLEKELYSAGLARVDIERAADNVAVTVHVAKPGVVIGRGG ERIRVLREELAKLTGKNVALNVQEVQNPNLSAPLVAQRVA EQIERRFAVRRAIKQAVQRVMESGAKGAKVIVSGRIGGAE QARTEWAAQGRVPLHTLRANIDYGFALARTTYGVLGVKAY IFLGEVI D:  GRYIGPVCRLCRREGVKLYLKGERCYSPKCAMERRPYPPG QHGQKRARRPSDYAVRLREKQKLRRIYGISERQFRNLFEE ASKKKGVTGSVFLGLLESRLDNVVYRLGFAVSRRQARQLV RHGHITVNGRRVDLPSYRVRPGDEIAVAEKSRNLELIRQN LEAMKGRKVGPWLSLDVEGMKGKFLRLPDREDLALPVNEQ LVIEFYSR E:  DFEEKMILIRRTARMQAGGRRFRFGALVVVGDRQGRVGLG FGKAPEVPLAVQKAGYYARRNMVEVPLQNGTIPHEIEVEF GASKIVLKPAAPGTGVIAGAVPRAILELAGVTDILTKELG SRNPINIAYATMEALRQLRTKADVERLRKGE F:  MRRYEVNIVLNPNLDQSQLALEKEIIQRALENYGARVEKV EELGLRRLAYPIAKDPQGYFLWYQVEMPEDRVNDLARELR IRDNVRRVMVVKSQEPFLANA G:  ARRRRAEVRQLQPDLVYGDVLVTAFINKIMRDGKKNLAAR IFYDACKIIQEKTGQEPLKVFKQAVENVKPRMEVRSRRVG GANYQVPMEVSPRRQQSLALRWLVQAANQRPERRAAVRIA HELMDAAEGKGGAVKKKEDVERMAEANRAYAHYRW H:  MLTDPIADMLTRIRNATRVYKESTDVPASRFKEEILRILA REGFIKGYERVDVDGKPYLRVYLKYGPRRQGPDPRPEQVI HHIRRISKPGRRVYVGVKEIPRVRRGLGIAILSTSKGVLT DREARKLGVGGELICEVW I:  EQYYGTGRRKEAVARVFLRPGNGKVTVNGQDFNEYFQGLV RAVAALEPLRAVDALGRFDAYITVRGGGKSGQIDAIKLGI ARALVQYNPDYRAKLKPLGFLTRDARVVERKKYGKHKARR APQYSKR J:  KIRIKLRGFDHKTLDASAQKIVEAARRSGAQVSGPIPLPT RVRRFTVIRGPFKHKDSREHFELRTHNRLVDIINPNRKTI EQLMTLDLPTGVEIEIKTV K:  KRQVASGRAYIHASYNNTIVTITDPDGNPITWSSGGVIGY KGSRKGTPYAAQLAALDAAKKAMAYGMQSVDVIVRGTGAG REQAIRALQASGLQVKSIVDDTPVPHNGCRPKKKFRKAS L:  PTINQLVRKGREKVRKKSKVPALKGAPFRRGVCTVVRTVT PKKPNSALRKVAKVRLTSGYEVTAYIPGEGHNLQEHSVVL IRGGRVKDLPGVRYHIVRGVYDAAGVKDRKKSRSKYGTKK PKEAA M:  ARIAGVEIPRNKRVDVALTYIYGIGKARAKEALEKTGINP ATRVKDLTEAEVVRLREYVENTWKLEGELRAEVAANIKRL MDIGCYRGLRHRRGLPVRGQRTRTNARTRKGPRKTVAGKK KAPRK N:  ARKALIEKAKRTPKFKVRAYTRCVRCGRARSVYRFFGLCR ICLRELAHKGQLPGVRKASW O:  PITKEEKQKVIQEFARFPGDTGSTEVQVALLTLRINRLSE HLKVHKKDHHSHRGLLMMVGQRRRLLRYLQREDPERYRAL IEKLGIRG P:  MVKIRLARFGSKHNPHYRIVVTDARRKRDGKYIEKIGYYD PRKTTPDWLKVDVERARYWLSVGAQPTDTARRLLRQAGVF RQEA Q:  PKKVLTGVVVSDKMQKTVTVLVERQFPHPLYGKVIKRSKK YLAHDPEEKYKLGDVVEIIESRPISKRKRFRVLRLVESGR MDLVEKYLIRRQNYQSLSKRGGKA R:  PSRKAKVKATLGEFDLRDYRNVEVLKRFLSETGKILPRRR TGLSGKEQRILAKTIKRARILGLLPFTEKLVRK S:  PRSLKKGVFVDDHLLEKVLELNAKGEKRLIKTWSRRSTIV PEMVGHTIAVYNGKQHVPVYITENMVGHKLGEFAPTRTYR G T:  RNLSALKRHRQSLKRRLRNKAKKSAIKTLSKKAVQLAQEG KAEEALKIMRKAESLIDKAAKGSTLHKNAAARRKSRLMRK VRQLLEAAGAPLIGGGLSA V:  GKGDRRTRRGKIWRGTYGKYRPRKK Description Functional site 1) chain V residue 4 type sequence D description BINDING SITE FOR RESIDUE MG A 2616 source : HC6 2) chain L residue 44 type sequence P description BINDING SITE FOR RESIDUE MG A 2624 source : IC5 3) chain L residue 45 type sequence N description BINDING SITE FOR RESIDUE MG A 2625 source : IC6 4) chain Q residue 64 type sequence I description BINDING SITE FOR RESIDUE MG A 2627 source : IC8 5) chain L residue 11 type sequence R description BINDING SITE FOR RESIDUE MG A 2637 source : JC9 6) chain Q residue 31 type sequence Y description BINDING SITE FOR RESIDUE MG A 2637 source : JC9 7) chain J residue 55 type sequence K description BINDING SITE FOR RESIDUE MG A 2641 source : KC4 8) chain S residue 80 type sequence R description BINDING SITE FOR RESIDUE MG A 2643 source : KC6 9) chain Q residue 38 type sequence S description BINDING SITE FOR RESIDUE MG A 2651 source : LC5 10) chain Q residue 66 type sequence K description BINDING SITE FOR RESIDUE MG A 2652 source : LC6 11) chain M residue 100 type sequence Q description BINDING SITE FOR RESIDUE MG A 2664 source : MC9 12) chain G residue 105 type sequence Q description BINDING SITE FOR RESIDUE MG A 2669 source : NC5 13) chain T residue 28 type sequence T description BINDING SITE FOR RESIDUE MG A 2705 source : QC9 14) chain L residue 40 type sequence T description BINDING SITE FOR RESIDUE RPO A 2800 source : RC2 15) chain B residue 90 type sequence R description BINDING SITE FOR RESIDUE MG B 1235 source : RC3 16) chain D residue 8 type sequence C description BINDING SITE FOR RESIDUE ZN D 1209 source : RC4 17) chain D residue 11 type sequence C description BINDING SITE FOR RESIDUE ZN D 1209 source : RC4 18) chain D residue 18 type sequence L description BINDING SITE FOR RESIDUE ZN D 1209 source : RC4 19) chain D residue 25 type sequence C description BINDING SITE FOR RESIDUE ZN D 1209 source : RC4 20) chain D residue 30 type sequence C description BINDING SITE FOR RESIDUE ZN D 1209 source : RC4 21) chain E residue 64 type sequence E description BINDING SITE FOR RESIDUE MG E 1151 source : RC5 22) chain E residue 66 type sequence P description BINDING SITE FOR RESIDUE MG E 1151 source : RC5 23) chain F residue 80 type sequence R description BINDING SITE FOR RESIDUE MG F 1102 source : RC6 24) chain F residue 82 type sequence R description BINDING SITE FOR RESIDUE MG F 1102 source : RC6 25) chain F residue 85 type sequence V description BINDING SITE FOR RESIDUE MG F 1102 source : RC6 26) chain H residue 14 type sequence R description BINDING SITE FOR RESIDUE MG H 1139 source : RC7 27) chain H residue 82 type sequence H description BINDING SITE FOR RESIDUE MG H 1139 source : RC7 28) chain H residue 83 type sequence I description BINDING SITE FOR RESIDUE MG H 1139 source : RC7 29) chain K residue 16 type sequence N description BINDING SITE FOR RESIDUE MG K 1120 source : RC8 30) chain K residue 42 type sequence G description BINDING SITE FOR RESIDUE MG K 1120 source : RC8 31) chain K residue 110 type sequence R description BINDING SITE FOR RESIDUE MG K 1121 source : RC9 32) chain L residue 39 type sequence V description BINDING SITE FOR RESIDUE MG L 1125 source : SC1 33) chain L residue 40 type sequence T description BINDING SITE FOR RESIDUE MG L 1125 source : SC1 34) chain L residue 20 type sequence V description BINDING SITE FOR RESIDUE MG L 1126 source : SC2 35) chain L residue 22 type sequence A description BINDING SITE FOR RESIDUE MG L 1126 source : SC2 36) chain L residue 26 type sequence A description BINDING SITE FOR RESIDUE MG L 1126 source : SC2 37) chain M residue 19 type sequence T description BINDING SITE FOR RESIDUE MG M 1126 source : SC3 38) chain M residue 21 type sequence I description BINDING SITE FOR RESIDUE MG M 1126 source : SC3 39) chain M residue 22 type sequence Y description BINDING SITE FOR RESIDUE MG M 1126 source : SC3 40) chain M residue 24 type sequence I description BINDING SITE FOR RESIDUE MG M 1126 source : SC3 41) chain N residue 23 type sequence C description BINDING SITE FOR RESIDUE ZN N 1061 source : SC4 42) chain N residue 26 type sequence C description BINDING SITE FOR RESIDUE ZN N 1061 source : SC4 43) chain N residue 28 type sequence R description BINDING SITE FOR RESIDUE ZN N 1061 source : SC4 44) chain N residue 39 type sequence C description BINDING SITE FOR RESIDUE ZN N 1061 source : SC4 45) chain N residue 42 type sequence C description BINDING SITE FOR RESIDUE ZN N 1061 source : SC4 46) chain T residue 4 type sequence S description BINDING SITE FOR RESIDUE MG T 1100 source : SC5 47) chain T residue 5 type sequence A description BINDING SITE FOR RESIDUE MG T 1100 source : SC5 48) chain G residue 19-45 type prosite sequence DVLVTAFINKIMRDGKKNLAARIFYDA description RIBOSOMAL_S7 Ribosomal protein S7 signature. DvLvtaFInkimrdGKKnlaarIFydA source prosite : PS00052 49) chain H residue 108-125 type prosite sequence GIAILSTSKGVLTDREAR description RIBOSOMAL_S8 Ribosomal protein S8 signature. GiaILSTSkGVLtdreAR source prosite : PS00053 50) chain K residue 85-107 type prosite sequence IRALQASGLQVKSIVDDTPVPHN description RIBOSOMAL_S11 Ribosomal protein S11 signature. IrALqaS.GLqVksivDdTPvPHN source prosite : PS00054 51) chain L residue 42-49 type prosite sequence KKPNSALR description RIBOSOMAL_S12 Ribosomal protein S12 signature. KkPNSAlR source prosite : PS00055 52) chain Q residue 53-65 type prosite sequence GDVVEIIESRPIS description RIBOSOMAL_S17 Ribosomal protein S17 signature. GDvVeIiEsRPIS source prosite : PS00056 53) chain R residue 17-40 type prosite sequence RDYRNVEVLKRFLSETGKILPRRR description RIBOSOMAL_S18 Ribosomal protein S18 signature. RDYrn.VevLkrFLSEt.GKIlprRR source prosite : PS00057 54) chain R residue 51-66 type prosite sequence LAKTIKRARILGLLPF description ALDOKETO_REDUCTASE_3 Aldo/keto reductase family putative active site signature. LAKTIKraRIlGLlPF source prosite : PS00063 55) chain S residue 52-76 type prosite sequence NGKQHVPVYITENMVGHKLGEFAPT description RIBOSOMAL_S19 Ribosomal protein S19 signature. NGKqhvpvyItenmVGhkLGEFapT source prosite : PS00323 56) chain I residue 66-84 type prosite sequence GGGKSGQIDAIKLGIARAL description RIBOSOMAL_S9 Ribosomal protein S9 signature. GGGksGQidAiklGiARAL source prosite : PS00360 57) chain J residue 25-40 type prosite sequence ARRSGAQVSGPIPLPT description RIBOSOMAL_S10 Ribosomal protein S10 signature. ArrsGAqvsGPIpLPT source prosite : PS00361 58) chain O residue 38-68 type prosite sequence LSEHLKVHKKDHHSHRGLLMMVGQRRRLLRY description RIBOSOMAL_S15 Ribosomal protein S15 signature. LseHLkvhKkDhhShrgLlmMvgqrrrLlrY source prosite : PS00362 59) chain N residue 22-44 type prosite sequence RCVRCGRARSVYRFFGLCRICLR description RIBOSOMAL_S14 Ribosomal protein S14 signature. R.CvrcgrarsvyrfFGLCRiCLR source prosite : PS00527 60) chain C residue 162-196 type prosite sequence ARTEWAAQGRVPLHTLRANIDYGFALARTTYGVLG description RIBOSOMAL_S3 Ribosomal protein S3 signature. ARtewaaqGrVplHt..LranIDygfalarTtyGvlG source prosite : PS00548 61) chain E residue 19-51 type prosite sequence GRRFRFGALVVVGDRQGRVGLGFGKAPEVPLAV description RIBOSOMAL_S5 Ribosomal protein S5 signature. GRrfrFgAlvVVGDrq.GrVGlGfgkap.EVpl.AV source prosite : PS00585 62) chain D residue 96-120 type prosite sequence LESRLDNVVYRLGFAVSRRQARQLV description RIBOSOMAL_S4 Ribosomal protein S4 signature. LEsRLdnvVYRlgfAvSrrqARqLV source prosite : PS00632 63) chain M residue 87-100 type prosite sequence RGLRHRRGLPVRGQ description RIBOSOMAL_S13_1 Ribosomal protein S13 signature. RGlRHrrGlpVRGQ source prosite : PS00646 64) chain B residue 1-12 type prosite sequence VKELLEAGVHFG description RIBOSOMAL_S2_1 Ribosomal protein S2 signature 1. VkELLEAGVHFG source prosite : PS00962 65) chain F residue 44-53 type prosite sequence GLRRLAYPIA description RIBOSOMAL_S6 Ribosomal protein S6 signature. GlRRLAYpIA source prosite : PS01048 66) chain N residue 23 type BINDING sequence C description BINDING => ECO:0000269|PubMed:11866529 source Swiss-Prot : SWS_FT_FI1 67) chain N residue 26 type BINDING sequence C description BINDING => ECO:0000269|PubMed:11866529 source Swiss-Prot : SWS_FT_FI1 68) chain N residue 39 type BINDING sequence C description BINDING => ECO:0000269|PubMed:11866529 source Swiss-Prot : SWS_FT_FI1 69) chain N residue 42 type BINDING sequence C description BINDING => ECO:0000269|PubMed:11866529 source Swiss-Prot : SWS_FT_FI1

Display surface Download Links