eF-site ID 4aw6-D PDB Code 4aw6 Chain D click to enlarge Title Crystal structure of the human nuclear membrane zinc metalloprotease ZMPSTE24 (FACE1) Classification HYDROLASE Compound CAAX PRENYL PROTEASE 1 HOMOLOG Source Homo sapiens (Human) (FACE1_HUMAN) Sequence D:  LWEMPAEKRIFGAVLLFSWTVYLWETFLAQRQRRIYKTTT HVPPELGQIMDSETFEKSRLYQLDKSTFSFWSGLYSETEG TLILLFGGIPYLWRLSGRPEYEITQSLVFLLLATLFSALA GLPWSLYNTFVIEEKHGFNQQTLGFFMKDAIKKFVVTQCI LLPVSSLLLYIIKIGGDYFFIYAWLFTLVVSLVLVTIYAD YIAPLFDKFTPLPEGKLKEEIEVMAKSIDFPLTKVYVVEG SKRSSHSNAYFYGFFKNKRIVLFDTLLEQGCKNEEVLAVL GHELGHWKLGHTVKNIIISQMNSFLCFFLFAVLIGRKELF AAFGFYDSQPTLIGLLIIFQFIFSPYNEVLSFCLTVLSRR FEFQADAFAKKLGKAKDLYSALIKLNKDNLGFPVSDWLFS MWHYSHPPLLERLQALKT Description Functional site 1) chain D residue 335 type sequence H description BINDING SITE FOR RESIDUE ZN D 1472 source : AC5 2) chain D residue 336 type sequence E description BINDING SITE FOR RESIDUE ZN D 1472 source : AC5 3) chain D residue 339 type sequence H description BINDING SITE FOR RESIDUE ZN D 1472 source : AC5 4) chain D residue 415 type sequence E description BINDING SITE FOR RESIDUE ZN D 1472 source : AC5 5) chain D residue 271 type sequence F description BINDING SITE FOR RESIDUE PC1 D 1473 source : AC6

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