eF-site ID 4ava-A
PDB Code 4ava
Chain A

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Title Crystal structure of protein lysine acetyltransferase Rv0998 from Mycobacterium tuberculosis
Classification TRANSFERASE
Compound LYSINE ACETYLTRANSFERASE
Source Mycobacterium tuberculosis (O05581_MYCTU)
Sequence A:  DGIAELTGARVEDLAGMDVFQGCPAEGLVSLAASVQPLRA
AAGQVLLRQGEPAVSFLLISSGSAEVSHVGDDGVAIIARA
LPGMIVGEIALLRDSPRSATVTTIEPLTGWTGGRGAFATM
VHIPGVGERLLRTARQRLAAFVSPIPVRLADGTQLMLRPV
LPGDRERTVHGHIQFSGETLYRRFMSPALMHYLSEVDYVD
HFVWVVTDGSDPVADARFVRDETDPTVAEIAFTVADAYQG
RGIGSFLIGALSVAARVDGVERFAARMLSDNVPMRTIMDR
YGAVWQREDVGVITTMIDVPGPGELSLGREMVDQINRVAR
QVIEAVG
Description (1)  LYSINE ACETYLTRANSFERASE


Functional site

1) chain A
residue 136
type
sequence R
description BINDING SITE FOR RESIDUE ACO A 1334
source : AC1

2) chain A
residue 140
type
sequence A
description BINDING SITE FOR RESIDUE ACO A 1334
source : AC1

3) chain A
residue 143
type
sequence V
description BINDING SITE FOR RESIDUE ACO A 1334
source : AC1

4) chain A
residue 145
type
sequence P
description BINDING SITE FOR RESIDUE ACO A 1334
source : AC1

5) chain A
residue 173
type
sequence H
description BINDING SITE FOR RESIDUE ACO A 1334
source : AC1

6) chain A
residue 236
type
sequence I
description BINDING SITE FOR RESIDUE ACO A 1334
source : AC1

7) chain A
residue 237
type
sequence A
description BINDING SITE FOR RESIDUE ACO A 1334
source : AC1

8) chain A
residue 238
type
sequence F
description BINDING SITE FOR RESIDUE ACO A 1334
source : AC1

9) chain A
residue 239
type
sequence T
description BINDING SITE FOR RESIDUE ACO A 1334
source : AC1

10) chain A
residue 240
type
sequence V
description BINDING SITE FOR RESIDUE ACO A 1334
source : AC1

11) chain A
residue 245
type
sequence Q
description BINDING SITE FOR RESIDUE ACO A 1334
source : AC1

12) chain A
residue 246
type
sequence G
description BINDING SITE FOR RESIDUE ACO A 1334
source : AC1

13) chain A
residue 247
type
sequence R
description BINDING SITE FOR RESIDUE ACO A 1334
source : AC1

14) chain A
residue 248
type
sequence G
description BINDING SITE FOR RESIDUE ACO A 1334
source : AC1

15) chain A
residue 249
type
sequence I
description BINDING SITE FOR RESIDUE ACO A 1334
source : AC1

16) chain A
residue 250
type
sequence G
description BINDING SITE FOR RESIDUE ACO A 1334
source : AC1

17) chain A
residue 251
type
sequence S
description BINDING SITE FOR RESIDUE ACO A 1334
source : AC1

18) chain A
residue 272
type
sequence R
description BINDING SITE FOR RESIDUE ACO A 1334
source : AC1

19) chain A
residue 277
type
sequence N
description BINDING SITE FOR RESIDUE ACO A 1334
source : AC1

20) chain A
residue 279
type
sequence P
description BINDING SITE FOR RESIDUE ACO A 1334
source : AC1

21) chain A
residue 280
type
sequence M
description BINDING SITE FOR RESIDUE ACO A 1334
source : AC1

22) chain A
residue 282
type
sequence T
description BINDING SITE FOR RESIDUE ACO A 1334
source : AC1

23) chain A
residue 283
type
sequence I
description BINDING SITE FOR RESIDUE ACO A 1334
source : AC1

24) chain A
residue 286
type
sequence R
description BINDING SITE FOR RESIDUE ACO A 1334
source : AC1

25) chain A
residue 173
type
sequence H
description BINDING SITE FOR RESIDUE ACT A 1335
source : AC2

26) chain A
residue 167
type
sequence E
description BINDING SITE FOR RESIDUE EDO A 1336
source : AC3

27) chain A
residue 220
type
sequence A
description BINDING SITE FOR RESIDUE EDO A 1336
source : AC3

28) chain A
residue 221
type
sequence D
description BINDING SITE FOR RESIDUE EDO A 1336
source : AC3

29) chain A
residue 241
type
sequence A
description BINDING SITE FOR RESIDUE EDO A 1336
source : AC3

30) chain A
residue 286
type
sequence R
description BINDING SITE FOR RESIDUE EDO A 1337
source : AC4

31) chain A
residue 312
type
sequence S
description BINDING SITE FOR RESIDUE EDO A 1337
source : AC4

32) chain A
residue 145
type
sequence P
description BINDING SITE FOR RESIDUE EDO A 1338
source : AC5

33) chain A
residue 147
type
sequence P
description BINDING SITE FOR RESIDUE EDO A 1338
source : AC5

34) chain A
residue 275
type
sequence S
description BINDING SITE FOR RESIDUE EDO A 1338
source : AC5

35) chain A
residue 276
type
sequence D
description BINDING SITE FOR RESIDUE EDO A 1338
source : AC5

36) chain A
residue 278
type
sequence V
description BINDING SITE FOR RESIDUE EDO A 1338
source : AC5

37) chain A
residue 95
type
sequence D
description BINDING SITE FOR RESIDUE EDO A 1339
source : AC6

38) chain A
residue 171
type
sequence H
description BINDING SITE FOR RESIDUE EDO A 1339
source : AC6

39) chain A
residue 172
type
sequence G
description BINDING SITE FOR RESIDUE EDO A 1339
source : AC6

40) chain A
residue 173
type
sequence H
description BINDING SITE FOR RESIDUE EDO A 1339
source : AC6

41) chain A
residue 237
type
sequence A
description BINDING SITE FOR RESIDUE EDO A 1339
source : AC6

42) chain A
residue 239
type
sequence T
description BINDING SITE FOR RESIDUE EDO A 1339
source : AC6

43) chain A
residue 215
type
sequence G
description BINDING SITE FOR RESIDUE PEG A 1340
source : AC7

44) chain A
residue 281
type
sequence R
description BINDING SITE FOR RESIDUE PEG A 1340
source : AC7

45) chain A
residue 285
type
sequence D
description BINDING SITE FOR RESIDUE PEG A 1340
source : AC7

46) chain A
residue 291
type
sequence W
description BINDING SITE FOR RESIDUE PEG A 1340
source : AC7

47) chain A
residue 133
type
sequence R
description BINDING SITE FOR RESIDUE PEG A 1341
source : AC8

48) chain A
residue 136
type
sequence R
description BINDING SITE FOR RESIDUE PEG A 1341
source : AC8

49) chain A
residue 137
type
sequence Q
description BINDING SITE FOR RESIDUE PEG A 1341
source : AC8

50) chain A
residue 140
type
sequence A
description BINDING SITE FOR RESIDUE PEG A 1341
source : AC8

51) chain A
residue 246
type
sequence G
description BINDING SITE FOR RESIDUE PEG A 1341
source : AC8

52) chain A
residue 214
type
sequence D
description BINDING SITE FOR RESIDUE MG A 1342
source : AC9

53) chain A
residue 88
type BINDING
sequence G
description BINDING => ECO:0000269|PubMed:22773105, ECO:0007744|PDB:4AVB, ECO:0007744|PDB:4AVC
source Swiss-Prot : SWS_FT_FI1

54) chain A
residue 98
type BINDING
sequence R
description BINDING => ECO:0000269|PubMed:22773105, ECO:0007744|PDB:4AVB, ECO:0007744|PDB:4AVC
source Swiss-Prot : SWS_FT_FI1

55) chain A
residue 138
type BINDING
sequence R
description BINDING => ECO:0000269|PubMed:22773105, ECO:0007744|PDB:4AVB, ECO:0007744|PDB:4AVC
source Swiss-Prot : SWS_FT_FI1

56) chain A
residue 173
type BINDING
sequence H
description BINDING => ECO:0000305|PubMed:22773105
source Swiss-Prot : SWS_FT_FI2

57) chain A
residue 238
type BINDING
sequence F
description BINDING => ECO:0000305|PubMed:22773105
source Swiss-Prot : SWS_FT_FI2

58) chain A
residue 246
type BINDING
sequence G
description BINDING => ECO:0000305|PubMed:22773105
source Swiss-Prot : SWS_FT_FI2

59) chain A
residue 277
type BINDING
sequence N
description BINDING => ECO:0000305|PubMed:22773105
source Swiss-Prot : SWS_FT_FI2

60) chain A
residue 286
type BINDING
sequence R
description BINDING => ECO:0000305|PubMed:22773105
source Swiss-Prot : SWS_FT_FI2

61) chain A
residue 214
type BINDING
sequence D
description BINDING => ECO:0000269|PubMed:22773105
source Swiss-Prot : SWS_FT_FI3

62) chain A
residue 87-104
type prosite
sequence VGEIALLRDSPRSATVTT
description CNMP_BINDING_2 Cyclic nucleotide-binding domain signature 2. VGEiALlrdsp......RSAtVtT
source prosite : PS00889


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