eF-site ID 4aq3-E PDB Code 4aq3 Chain E click to enlarge Title HUMAN BCL-2 WITH PHENYLACYLSULFONAMIDE INHIBITOR Classification APOPTOSIS Compound APOPTOSIS REGULATOR BCL-2, BCL-2-LIKE PROTEIN 1 Source null (BCLX_HUMAN) Sequence E:  DNREIVMKYIHYKLSQRGYEWDAVVHLALRQAGDDFSRRY RGDFAEMSSQLHLTPFTARGRFATVVEELFRDGVNWGRIV AFFEFGGVMCVESVNREMSPLVDNIALWMTEYLNRHLHTW IQDNGGWDAFVELYG Description (1)  APOPTOSIS REGULATOR BCL-2, BCL-2-LIKE PROTEIN 1 Functional site 1) chain E residue 58 type sequence Q description BINDING SITE FOR RESIDUE 398 A 1163 source : AC1 2) chain E residue 160 type sequence L description BINDING SITE FOR RESIDUE 398 A 1163 source : AC1 3) chain E residue 161 type sequence Y description BINDING SITE FOR RESIDUE 398 A 1163 source : AC1 4) chain E residue 162 type sequence G description BINDING SITE FOR RESIDUE 398 A 1163 source : AC1 5) chain E residue 82 type sequence P description BINDING SITE FOR RESIDUE 398 B 1163 source : AC2 6) chain E residue 63 type sequence F description BINDING SITE FOR RESIDUE 398 E 1163 source : AC5 7) chain E residue 67 type sequence Y description BINDING SITE FOR RESIDUE 398 E 1163 source : AC5 8) chain E residue 70 type sequence D description BINDING SITE FOR RESIDUE 398 E 1163 source : AC5 9) chain E residue 74 type sequence M description BINDING SITE FOR RESIDUE 398 E 1163 source : AC5 10) chain E residue 92 type sequence V description BINDING SITE FOR RESIDUE 398 E 1163 source : AC5 11) chain E residue 95 type sequence E description BINDING SITE FOR RESIDUE 398 E 1163 source : AC5 12) chain E residue 108 type sequence A description BINDING SITE FOR RESIDUE 398 E 1163 source : AC5 13) chain E residue 54 type MOD_RES sequence L description Phosphothreonine; by MAPK8 => ECO:0000269|PubMed:18570871 source Swiss-Prot : SWS_FT_FI1 14) chain E residue 72 type MOD_RES sequence A description Phosphoserine; by MAPK8 => ECO:0000269|PubMed:18570871 source Swiss-Prot : SWS_FT_FI3 15) chain E residue 55 type MOD_RES sequence A description Phosphoserine; by MAPK8 and PKC => ECO:0000269|PubMed:18570871 source Swiss-Prot : SWS_FT_FI2

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