|
|
eF-site ID
|
4aaf-A |
|
PDB Code
|
4aaf |
|
Chain
|
A |
|
click to enlarge
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Title
|
Crystal structure of the mutant D75N I-CreI in complex with an altered target (The four central bases, 2NN region, are composed by TGCA from 5' to 3') |
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Classification
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HYDROLASE/DNA |
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Compound
|
DNA ENDONUCLEASE I-CREI |
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Source
|
Chlamydomonas reinhardtii (Chlamydomonas smithii) (4AAF) |
|
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Sequence
|
A: |
NTKYNKEFLLYLAGFVDGDGSIIAQIKPNQSYKFKHQLSL
TFQVTQKTQRRWFLDKLVDEIGVGYVRDRGSVSNYILSEI
KPLHNFLTQLQPFLKLKQKQANLVLKIIEQLPSAKESPDK
FLEVCTWVDQIAALNDSKTRKTTSETVRAVL
|
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Description
|
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Functional site
|
|
|
1)
|
chain |
A |
| residue |
138 |
| type |
|
| sequence |
S
|
| description |
BINDING SITE FOR RESIDUE EDO E 1525
|
| source |
: AC1
|
|
|
2)
|
chain |
A |
| residue |
139 |
| type |
|
| sequence |
K
|
| description |
BINDING SITE FOR RESIDUE EDO E 1525
|
| source |
: AC1
|
|
|
3)
|
chain |
A |
| residue |
140 |
| type |
|
| sequence |
T
|
| description |
BINDING SITE FOR RESIDUE EDO E 1525
|
| source |
: AC1
|
|
|
4)
|
chain |
A |
| residue |
19 |
| type |
catalytic |
| sequence |
G
|
| description |
233
|
| source |
MCSA : MCSA1
|
|
|
5)
|
chain |
A |
| residue |
20 |
| type |
catalytic |
| sequence |
D
|
| description |
233
|
| source |
MCSA : MCSA1
|
|
|
6)
|
chain |
A |
| residue |
19 |
| type |
BINDING |
| sequence |
G
|
| description |
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
7)
|
chain |
A |
| residue |
20 |
| type |
BINDING |
| sequence |
D
|
| description |
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
|